<?xml version="1.0" encoding="UTF-8"?><rss xmlns:atom="http://www.w3.org/2005/Atom" version="2.0"><channel><title>Anthropic News</title><link>https://www.anthropic.com/news</link><atom:link href="http://137.220.150.103:1200/anthropic/news" rel="self" type="application/rss+xml"></atom:link><description>Latest news from Anthropic - Powered by RSSHub</description><generator>RSSHub</generator><webMaster>contact@rsshub.app (RSSHub)</webMaster><language>en</language><lastBuildDate>Thu, 27 Aug 2026 19:21:14 GMT</lastBuildDate><ttl>60</ttl><item><title>Previewing the Model Hardware Standard</title><description>&lt;article&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__hero&quot;&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper&quot;&gt;&lt;article&gt;&lt;div class=&quot;&quot;&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__body&quot; data-theme=&quot;ivory&quot;&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column Body-module-scss-module__z40yvW__inline&quot;&gt;&lt;div class=&quot;Video-module-scss-module__qJNyFq__post-wrapper&quot;&gt;&lt;figure class=&quot;Video-module-scss-module__qJNyFq__post-video-container&quot;&gt;&lt;!--$!--&gt;&lt;template data-dgst=&quot;BAILOUT_TO_CLIENT_SIDE_RENDERING&quot;&gt;&lt;/template&gt;&lt;!--/$--&gt;&lt;/figure&gt;&lt;/div&gt;&lt;/div&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We’re opening a research preview of the Model Hardware Standard (MHS), a shared specification for AI agents to safely operate physical devices, to a first group of scientific research labs and advanced manufacturers. MHS enables AI agents to operate multiple lab and manufacturing instruments, such as microscopes, liquid handlers, and robotic arms, in parallel, and perform intricate tasks ranging from routine drug discovery experiments to laser calibration on a quantum computer. The development of MHS began as a collaboration between Anthropic and &lt;a href=&quot;https://www.hhmi.org/research/janelia&quot; target=&quot;_blank&quot; rel=&quot;noopener noreferrer&quot;&gt;HHMI Janelia Research Campus&lt;/a&gt;.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;It typically takes a lab or manufacturing facility weeks, if not months, to set up and integrate their hardware. Most devices don’t communicate with each other, instead requiring specialists to build bespoke integrations. MHS reduces this integration work to hours or minutes. And by incorporating AI into these tools, MHS also helps researchers and engineers more readily orchestrate autonomous, round-the-clock experiments and workflows, with agents able to reason through each step in an experiment, update parameters in real time, and, in some cases, recover from hardware errors without intervention.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We’re sharing an early version of MHS with partners across science, robotics, electronics, and manufacturing so we can collaborate to build safety evaluations and develop best practices for AI systems operating physical equipment, ahead of making the standard open source. MHS works with any device that has a programmable interface. It is also model-agnostic, and any agent harness can access it using standard protocols, such as the &lt;a href=&quot;https://www.anthropic.com/news/model-context-protocol&quot; target=&quot;_blank&quot; rel=&quot;noopener noreferrer&quot;&gt;Model Context Protocol&lt;/a&gt;. To apply for access to the research preview, &lt;a href=&quot;https://www.modelhardwarestandard.com/&quot; target=&quot;_blank&quot; rel=&quot;noopener noreferrer&quot;&gt;head here&lt;/a&gt;.&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;how-mhs-works&quot;&gt;How MHS works&lt;/h2&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column Body-module-scss-module__z40yvW__inline&quot;&gt;&lt;div class=&quot;Video-module-scss-module__qJNyFq__post-wrapper&quot;&gt;&lt;figure class=&quot;Video-module-scss-module__qJNyFq__post-video-container&quot;&gt;&lt;video autoplay=&quot;&quot; controls=&quot;&quot; playsinline=&quot;&quot; muted=&quot;&quot; loop=&quot;&quot; src=&quot;https://cdn.sanity.io/files/4zrzovbb/website/af63049620774e379536a9bb28df7304c62f86af.mp4&quot;&gt;&lt;/video&gt;&lt;figcaption class=&quot;caption&quot;&gt;Before and after the Model Hardware Standard (MHS).&lt;/figcaption&gt;&lt;/figure&gt;&lt;/div&gt;&lt;/div&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Getting multiple devices in a lab or on a factory floor to communicate with one another can be challenging, even setting aside the added difficulty of integrating AI into the setup. Each device tends to have its own programming interface, and so far there has been no standardized way to integrate them. And once the devices &lt;em&gt;are &lt;/em&gt;connected, there is no common way for them to share data with an AI agent, nor to let the agent operate them safely. &lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;MHS addresses these challenges by introducing a standardized driver: software that translates between a computer’s operating system and a hardware device. The MHS driver uses a simple set of primitives—commands like “read” (for example, “get temperature”) or “write” (for example, “set temperature”)—that any hardware device can understand and act on. And it makes each device discoverable in a standard format, so that devices and agents can find each other and communicate across networks without needing a bespoke “translator” program in between.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;The MHS driver also helps an AI agent understand how to use a device it has never seen before, giving it information about machine characteristics that may not be discernable from code alone (for example, the weight of a robot arm, which is important for knowing how to manipulate it safely). To date, much of this information has been stored in paper manuals, on a user’s computer, or as tacit knowledge. But the MHS driver contains tags that let the user write this information directly in natural language (users can either do this themselves, or by chatting to an agent that interviews them about their hardware setup). With the information from these tags, the MHS driver then automatically produces a reference file with information about a device’s general characteristics, such as what it can measure, what can be adjusted, and what safety limits will be enforced. This file gives the agent everything it needs to know to operate the device.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;After the devices are connected and the agent knows how to use each one, the agent needs a way to control the hardware. For MHS, there are three such mechanisms: MCP, the command line interface, and code files (APIs). These work together to enable orchestration across multiple devices via a single line of code. &lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Once the agent can control the devices, it’s able to receive operating data from each one and supervise and direct the work at a high level. The agent can sequence steps across instruments, monitor results, and adjust parameters as conditions change in real time. When the agent needs to execute long-running tasks or operate devices faster than its online reasoning would allow, it can chain together driver commands from one or more devices in code files. This allows the devices to carry out operations themselves, without the agent needing to reason at every step.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;As we’ve tested MHS, we’ve found that Claude interacts with experiments and hardware in an exploratory manner, much as a scientist would. For example, we observed Claude make an adjustment to a laser, observe the results through a camera to assess how its adjustment moved the laser beam, and repeat the process, seeking to understand the sequence of events. Claude then packaged what it learned into code files, writing a deterministic script that let it align the laser without having to reason at each step, so the whole process could run as a single command.&lt;/p&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column Body-module-scss-module__z40yvW__inline&quot;&gt;&lt;div class=&quot;Video-module-scss-module__qJNyFq__post-wrapper&quot;&gt;&lt;figure class=&quot;Video-module-scss-module__qJNyFq__post-video-container&quot;&gt;&lt;!--$!--&gt;&lt;template data-dgst=&quot;BAILOUT_TO_CLIENT_SIDE_RENDERING&quot;&gt;&lt;/template&gt;&lt;!--/$--&gt;&lt;/figure&gt;&lt;/div&gt;&lt;/div&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;early-examples-from-mhs&quot;&gt;Early examples from MHS&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We are only just beginning to see what people can do with frontier models and MHS, but our hope is that the standard can be of use to researchers, engineers, and other practitioners in speeding up the process of discovery and experimentation in any domain that uses devices with a programmable interface.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;As we developed MHS, we shared it with a handful of labs and hardware manufacturers in biotech, robotics, quantum computing, and other fields. Across these early projects, we saw MHS reduce the time it took to integrate devices, make it possible to iterate faster in a variety of experimental settings, and assist with the live operation of machines and real-time fault detection. Below, our partners share the details of some of their early projects involving MHS. &lt;/p&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column&quot;&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-wrapper&quot;&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-container&quot;&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-track&quot;&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item bg-ivory-medium&quot;&gt;&lt;h3 class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-title headline-6&quot;&gt;Genentech: Implementing MHS for lab automation&lt;/h3&gt;&lt;div class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-overview body-3&quot;&gt;&lt;p class=&quot;body-2 serif body-2&quot;&gt;&lt;em&gt;Researchers at Genentech implemented and tested MHS as a proof of concept for automating the BCA protein assay, a standard procedure to measure total protein concentration in a sample, which requires coordinating across a liquid handler, a robotic arm, and a plate reader.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;footer class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-footer&quot;&gt;&lt;button class=&quot;Button-module-scss-module__f9ZZrG__button Button-module-scss-module__f9ZZrG__small Button-module-scss-module__f9ZZrG__tertiary Button-module-scss-module__f9ZZrG__iconRight&quot; 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width=&quot;20&quot; height=&quot;20&quot; viewBox=&quot;0 0 20 20&quot;&gt;&lt;path transform=&quot;translate(3.7, 3.7)&quot; d=&quot;M0.45 0C0.698528 1.25348e-08 0.9 0.201472 0.9 0.45V12.15L0.891211 12.2405C0.849337 12.4457 0.667542 12.6 0.45 12.6C0.232458 12.6 0.0506628 12.4457 0.00878906 12.2405L0 12.15V0.45C1.25348e-08 0.201472 0.201472 -2.68736e-10 0.45 0ZM7.42236 1.86152C7.60284 1.75552 7.83937 1.78693 7.98486 1.94854C8.1304 2.11024 8.13662 2.34881 8.01211 2.51719L7.95147 2.58486L4.32334 5.85H12.15C12.3985 5.85 12.6 6.05147 12.6 6.3C12.6 6.54853 12.3985 6.75 12.15 6.75H4.32334L7.95147 10.0151C8.13615 10.1814 8.15111 10.4668 7.98486 10.6515C7.8186 10.8361 7.53325 10.8511 7.34854 10.6849L2.84854 6.63486L2.78525 6.56455C2.73 6.48837 2.7 6.3957 2.7 6.3C2.7 6.17245 2.75374 6.05047 2.84854 5.96514L7.34854 1.91514L7.42236 1.86152Z&quot; fill=&quot;#5E5D59&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/button&gt;&lt;/header&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-body body-2&quot;&gt;&lt;section class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study&quot;&gt;&lt;h3 class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-header headline-4&quot;&gt;Genentech: Implementing MHS for lab automation&lt;/h3&gt;&lt;div class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-overview body-2 serif&quot;&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;em&gt;Researchers at Genentech implemented and tested MHS as a proof of concept for automating the BCA protein assay, a standard procedure to measure total protein concentration in a sample, which requires coordinating across a liquid handler, a robotic arm, and a plate reader.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;/section&gt;&lt;p class=&quot;body-2 serif&quot;&gt;For half a century, Genentech has been tackling some of the most formidable challenges in science and medicine. In 1977, our scientists successfully produced somatostatin—a peptide hormone that regulates insulin and glucagon, growth hormone, and digestive tract functions in humans—in E. coli bacteria using recombinant DNA technology, proving that bacteria could be reprogrammed into bio-factories for medicines. Shortly thereafter, we synthesized recombinant human insulin, which in 1982 became the first genetically engineered therapeutic ever approved by the FDA. Since then, our commitment to basic research and patient care has pushed us to discover breakthrough therapies for cancer, multiple sclerosis, and other complex diseases.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;This work requires rigorous experimentation in our drug discovery labs, often with large-scale automated systems capable of running high-throughput assays and testing many variables in parallel. These systems are made up of highly specialized lab robots—liquid handlers, robotic arms, microplate readers, and the like—that need to be carefully calibrated, iteratively tested, and supplied with complex programming logic in order to carry out experiments with precision. Currently, setting up these automated systems is a manual, time-consuming process that can take weeks or even months, limiting the number of scientific ideas our researchers can test.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;To address this core bottleneck between experimental design and automated execution, we implemented MHS for lab automation with Anthropic. This open framework is designed to standardize AI-to-hardware communication, enabling scientists to interact with specialized lab robots using natural language and eliminating the need to write custom robotic code. Our ultimate goal is to build autonomous labs where AI handles the tedious, mechanical parts of experiment execution at scale so that our scientists can focus on the many creative aspects of accelerating drug discovery that rely on human judgement, such as experimental design, interpretation, decision making, and the invention of new lab approaches.&lt;/p&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Automating the BCA assay as a proof-of-concept&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;We first implemented MHS on a large robotic workstation designed around a liquid handler. We wanted to see whether MHS could speed up the automation of the bicinchoninic acid (BCA) protein assay, a standard procedure used to measure total protein concentration in a sample. The procedure involves three instruments: a liquid handler to make precise fluid transfers, a robotic arm to move labware, and a microplate reader to measure optical absorbance, or how much light a sample absorbs at a given wavelength. We deployed MHS across all three devices, using Claude to orchestrate the protocol and act as a central communication hub for the hardware. All experiments were conducted in standard 96-well microplates, a staple of automated lab equipment.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The BCA assay involves handling liquids with different physical properties, ranging from simple aqueous reagents to viscous, foamy protein samples. In our setup, we used bovine serum albumin (BSA) at known concentrations as our protein sample to serve as a reliable standard. Because these fluids behave differently under pressure and flow, pipetting must be done extremely precisely to ensure that an exact volume of solution is transferred. For example, BSA solutions are viscous and form bubbles at high flow rates—the speed at which a liquid moves through a pipette tip—which directly impacts how accurately the solution is pipetted into the plate. Virtually all automated scientific experiments start with optimizing such fluid dynamics for each protocol.&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1999&quot; height=&quot;1250&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/0aa7623ba0e545ce39e0de725583c0445ce6b76d-1999x1250.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;The automated experiment workflow. First, a scientist describes the experiment to Claude in plain language. Then, Claude plans and orchestrates the run, drawing on reusable skills and a knowledge base. Every instruction passes through MHS, which serves as the standard interface for each device. MHS then operates each instrument (the liquid handler, robotic arm, and microplate reader) and streams its state back to Claude. The orange ring shows the part of the experiment Claude executed in a closed loop. It set a flow rate and transferred dyed liquid to a plate, sent the plate down the stack and read absorbance, then scored its own transfer against an expert’s and adjusted the flow rate, converging on water ≈ 140 µL/s (0.016) and viscous BSA ≈ 10 µL/s (0.181).&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;As a starting point, we gave Claude the standard BCA assay protocol to establish a baseline against which to assess improvements. In this first test, Claude executed the protocol steps, but it selected generic liquid handling parameters with the same flow rate for both aqueous and viscous solutions, which caused bubbles to form in the viscous solution, resulting in inaccurate liquid transfers. We then asked Claude to autonomously optimize fluid dynamics for both plain water and viscous protein samples (BSA). We prompted the model with an experimental design to optimize the liquid transfer flow rate, asking it to explore our expert-defined range of flow rates by conducting trial transfers with dyed liquid and taking absorbance readings with the microplate reader to determine the optimal flow rate for each liquid type. Claude also had access to a “ground truth” transfer, performed by an expert in the same plate, and we asked it to minimize the difference between the expert’s results and its own. After performing the transfers, Claude calculated the root mean square error (RMSE) to quantify how accurate it had been (the lower, the better, with zero being the perfect score; if it aimed for 100 microliters but dispensed 98, that 2-microliter miss would count against the score).&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Claude independently executed these trial runs and analyzed the resulting plate reader data to get closer to the expert-performed transfers. For water, Claude concluded that a flow rate of ~140 µL/s was optimal (0.016 RMSE); for BSA, it arrived at 10 µL/s (0.181 RMSE)—parameters that our automation experts confirmed were reasonable for our setup. Ordinarily, performing this optimization requires an automation specialist to write custom programming logic for every single parameter set, iteratively analyzing the data until they find the right parameters.&lt;/p&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Autonomous error recovery and the limits of current AI models&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;During the experiment, Claude encountered several unexpected errors, including tip pickup failures and fluid detection errors, but managed to recover on its own—a capability that current scientific instruments mostly lack. However, these experiments also highlighted the current limits of AI models. Although they excel at general-purpose reasoning, they still struggle with physical, chemical, and biological constraints, particularly when troubleshooting errors that call for real-world physical intuition.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;An example of this type of limitation is the formation of bubbles during liquid handling. Although they may seem benign, bubbles create a cascade of challenges: if a protocol calls for aspirating 40μL of reagent but there are air bubbles in the liquid, the actual liquid volume transferred will be lower due to the space occupied by air. Furthermore, liquid-level sensors can trigger hardware errors when a pipette tip encounters foam instead of liquid; bubbles also distort the optical readings that are the final readout of the experiment.&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1999&quot; height=&quot;1125&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/943af4b43644ab0d213ba362eabd609c98cd8887-1999x1125.jpg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;Genentech scientists analyze plates for the presence of bubbles.&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;When it encountered runtime errors caused by bubbles during mixing, Claude’s default instinct was simply to retry the operation in the same plate well with different parameters. But this only agitated the fluid further and created more bubbles. Because Claude did not yet understand the underlying physics of the failure, we had to guide it towards parameters that handled the liquid more gently.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Once Claude was informed that the error code stemmed from physical bubbles in the liquid and that it needed to move to a clean well and reduce the number of mixing cycles in order to correct the error, it maintained that context for the rest of the run. We subsequently codified these takeaways into reusable liquid handling skills for Claude, which allowed it to select sensible default parameters for liquids with varying physical properties, reducing the number of liquid handling errors. These experiments highlighted the sorts of reasoning limits we can address by refining Claude’s software harness for lab automation.&lt;/p&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Towards autonomous discovery&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Although there is more work to be done to improve how Claude reasons about physical lab manipulations, this study proved to be a highly promising proof-of-concept. By assessing Claude’s decisions against our own domain expertise, we are generating the datasets we need to continuously improve models’ performance in automating lab experiments.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Going forward, we plan to evaluate Claude and MHS to orchestrate broader, end-to-end autonomous workflows in our drug discovery labs. We aim to build an autonomous discovery engine where scientists set the high-level biological intent, and AI agents help them coordinate the physical pipeline—generating hardware instructions, executing experiments autonomously, running closed-loop analysis, and delivering screen-ready models and screening data.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;To expand our scope and impact, we’ll need to implement MHS on additional hardware, such as centrifuges, automated incubators, analytical instruments, and sensors. We’ll also need to tune the agent harness so it understands the nuances of working across drug discovery from molecules to live, sensitive cells. And we’ll have to integrate other, custom models that monitor and adaptively optimize experiments around the clock based on real-time data. With AI handling the routine tasks of maintenance, quality control, and environmental monitoring, our scientists can focus more on high-level experimental design, reasoning, and invention—moving us one step closer to accelerating the discovery of life-saving medicines.&lt;/p&gt;&lt;h4 class=&quot;headline-6&quot;&gt;Acknowledgements&lt;/h4&gt;&lt;p class=&quot;body-2 serif&quot;&gt;We’d like to thank the Genentech scientists who contributed to this work, including Anupriya Tripathi, Matthew Bucci, Justin Nicola, and Corinne Gullekson.&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/footer&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item bg-ivory-medium&quot;&gt;&lt;h3 class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-title headline-6&quot;&gt;University of Washington Baker and Pinglay labs: Bringing AI agents to the bench&lt;/h3&gt;&lt;div class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-overview body-3&quot;&gt;&lt;p class=&quot;body-2 serif body-2&quot;&gt;&lt;em&gt;Zihao Song, a PhD student in the University of Washington Baker and Pinglay labs, used MHS to build a dashboard to remotely monitor his instruments; an AI agent-supervised qPCR (which copies a target DNA sequence through repeated cycles of heating and cooling) that watches amplification curves and halts the procedure at the right moment; and an integration between a robotic arm and a liquid handler for collision-free plate handoffs.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;footer class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-footer&quot;&gt;&lt;button class=&quot;Button-module-scss-module__f9ZZrG__button Button-module-scss-module__f9ZZrG__small Button-module-scss-module__f9ZZrG__tertiary Button-module-scss-module__f9ZZrG__iconRight&quot; aria-expanded=&quot;false&quot; aria-haspopup=&quot;dialog&quot;&gt;&lt;span class=&quot;caption&quot;&gt;Read more&lt;/span&gt;&lt;span class=&quot;Button-module-scss-module__f9ZZrG__icon&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon CaseStudyCarousel-module-scss-module__evH4Ta__flyout-trigger-icon&quot; width=&quot;20&quot; height=&quot;20&quot; viewBox=&quot;0 0 20 20&quot;&gt;&lt;path transform=&quot;translate(3.7, 3.7)&quot; 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fill=&quot;#5E5D59&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/button&gt;&lt;/header&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-body body-2&quot;&gt;&lt;section class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study&quot;&gt;&lt;h3 class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-header headline-4&quot;&gt;University of Washington Baker and Pinglay labs: Bringing AI agents to the bench&lt;/h3&gt;&lt;div class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-overview body-2 serif&quot;&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;em&gt;Zihao Song, a PhD student in the University of Washington Baker and Pinglay labs, used MHS to build a dashboard to remotely monitor his instruments; an AI agent-supervised qPCR (which copies a target DNA sequence through repeated cycles of heating and cooling) that watches amplification curves and halts the procedure at the right moment; and an integration between a robotic arm and a liquid handler for collision-free plate handoffs.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;/section&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;em&gt;De novo &lt;/em&gt;protein design—building proteins that have never been seen in nature from scratch—has found a steadily increasing number of applications in medicine, environmental protection, and more over the past several years. Two things have held it back, however: cost and throughput. These days, designing a protein like PETase (the enzyme that breaks down plastic) can cost as little as $0.01. But testing that protein at the bench is slow and expensive, costing around $100 and requiring a week of labor per candidate—which adds up, given that we test 1,000 candidates at a time.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;As a PhD student in the Baker and Pinglay labs at the University of Washington, I am working to develop high-throughput methods to reduce the cost per experiment and dramatically increase the number of &lt;em&gt;de novo&lt;/em&gt; protein designs that we can screen at once. But working at that scale comes with costs of its own. Every round I run, whether a multiplexed design assay or an active learning campaign on enzyme activity, presents the same two challenges: monitoring status and capacity. Currently, our monitoring instruments sit in different corners of the lab, so I can’t easily see how a run is going without physically walking over to each one to check. When something fails partway through the run—the HPLC halts on an error, for example, or a liquid handler misfires and ruins a plate—I seldom discover it right when it happens. By the time I notice, hours may have passed, and the experimental sample is unusable. And I own only one of most instruments, so a single machine sets the pace for a whole round of testing, and I spend hours feeding it by hand. The PCR step is the worst culprit in this capacity crunch: it only handles one plate at a time, and I have to change the plates every 90 minutes (which is how I sometimes end up moving plates at 4 a.m. instead of sleeping).&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The obvious fix is automation. But a research lab runs on flexibility, and that’s the one thing traditional automation cannot incorporate. A typical factory line might run one protocol 10,000 times, but my lab runs dozens of protocols a year, half of them new, which I must revise mid-run when the protein yield comes back far below what we assumed or a DNA assembly fails. Plus, my instruments come from different vendors, each with its own software, data format, and driver. Wiring them together is an integration problem that takes months to years and can cost anywhere from thousands to millions of dollars, putting it out of reach for most labs. There is no standard workflow to automate a protocol, and no affordable way to connect the instruments in most academic labs.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;To explore a low-cost, low-effort route around both, I combined MHS with an AI agent and ran a few demos in my lab. MHS essentially gave the agent eyes, hands, and a sense of timing: it could see the status of every instrument, run each one, and coordinate them to work together.&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1999&quot; height=&quot;912&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/34951ed9f87af7ef8b6d639b6e68f4f294e36804-1999x912.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;strong&gt;Figure 1.&lt;/strong&gt; Comparing an academic lab, an automated lab, and an MHS-based lab. Traditional labs run distributed instruments without a central scheduler. This is flexible but labor-intensive, with AI use limited to human-AI exchanges. Automated labs integrate instruments under a scheduler for near-autonomous operation, but they’re expensive and inflexible, keeping them out of reach of most academic labs, and AI-integrated versions are impractical beyond demos. MHS-based labs schedule all instruments through the standard, letting researchers monitor, control, and coordinate equipment; their AI-native architecture also lets agents actively participate in experiments.&lt;/figcaption&gt;&lt;/figure&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Case study 1: Taking the lab remote&lt;/h3&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1999&quot; height=&quot;1377&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/b451d157b06b5977035c6c711eea044c89c15f43-1999x1377.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;strong&gt;Figure 2.&lt;/strong&gt; Monitoring instruments using MHS. Researchers can monitor the status of all connected instruments directly through the MHS dashboard or via an AI agent. (left) Screenshot of the MHS dashboard; (right) output from Claude Code after connecting to MHS.&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Prior to MHS, I had to rove around the lab to monitor instruments. With MHS, instruments report their status to one dashboard, so I and my colleagues can check on the whole lab from a laptop, or even ask an AI agent from a mobile phone without setting foot inside (Figure 2).&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;This remote monitoring is especially helpful for experiments that demand sustained attention. Quantitative PCR (qPCR) is a good example. qPCR amplifies (i.e., copies) a target DNA sequence through repeated cycles of heating and cooling, with a fluorescent reporter that brightens as copies accumulate. DNA amplification follows an S-shaped curve: the copying doubles the target each cycle, so the signal stays flat while it is still faint, climbs steeply once there is enough to detect, then flattens again at the top of the curve as reagents run low and the copies stop doubling (the plateau). Letting the reaction run into that plateau distorts the DNA library, such that I can no longer glean accurate data about the final quantity of amplified DNA sequences. To avoid that, I need to watch the curve and halt the reaction at the right moment. This can take many hours and requires that I actively monitor the instrument’s screen.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;MHS addresses this tedium, monitoring and analyzing the amplification curves as they come in and reporting back in real time. It identifies the curve pattern and, at precisely the right junctures, asks the researcher whether to stop or continue. When told to stop, it halts the reaction and advances the instrument to the next step: a 4 °C hold, which keeps the DNA from degrading so it stays usable for downstream work (Figure 3). With an AI agent and MHS watching the curve, we can now focus on setting up downstream sequencing reactions at the bench or analyzing library enrichment data from other experiments in the office.&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1999&quot; height=&quot;1125&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/cd09961c40c470e184f91a38957262312caa2260-1999x1125.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;strong&gt;Figure 3.&lt;/strong&gt; Using an AI agent to monitor and control an experiment in real time via MHS. We worked with Claude Code to automate the execution of a qPCR protocol, transmitting the curve for each cycle to the chat box in real time for review. Upon receiving a stop command, the system halted the protocol and loaded a hold protocol. (All curves represent actual images from the interaction with Claude Code; some output has been truncated.)&lt;/figcaption&gt;&lt;/figure&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Case study 2: Coordinating instruments through a plate handoff&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Other experiments don’t need real-time monitoring, but they do require me to repeatedly load samples into a machine and take them out (for example, high-throughput DNA amplification, protein purification, and plate-based assays like ELISA). Loading a sample only takes a few seconds, but each run takes an hour or two, so I end up returning to the lab every hour just to swap plates.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;In an effort to free ourselves from full days tethered to the bench, we used an open-source robotic arm built on LeRobot, instrumented with MHS, to safely coordinate sample loading across multiple instruments. As a demo, I reproduced one routine handoff for a high-throughput experiment run. In this process, a liquid handler dispenses reaction reagents into a plate; the robot arm then lifts the finished plate off the deck and moves a fresh one into place, and the liquid handler dispenses again into the new plate. Claude Code controls and coordinates both instruments through MHS, running each step only once the previous one finishes, so the two instruments never collide during the handoff.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The demo worked as intended. After the liquid handler finished dispensing, the AI agent picked up the completion signal and, about 10 seconds later, triggered the arm’s next move, lifting the plate off the deck. Across repeated tests, the two instruments never collided: the arm never moved before dispensing had finished, and the handler never started before the arm had cleared the plate. Meanwhile, I watched the whole run on my office computer without touching anything. Handing off this kind of coordination to an AI agent, within the safety standards built into MHS, points to a future where an agent chains many such steps overnight while the bench runs unattended.&lt;/p&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Looking ahead&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Setting MHS up was faster and easier than I expected, especially given how my earlier automation attempts had gone—weeks spent evaluating platforms, chasing vendor support, learning and building glue code between instruments, and finally giving up. Connecting six instruments through MHS took under a week, including the time I spent writing drivers for them. Once they were connected, the AI agent worked with the instruments without much fussing on my part: it discovered each device, read its status, and called its operations without my having to hand-hold the interface. For someone who has spent years working around instruments that don’t talk to each other, that changed my day-to-day more than I anticipated. The time I used to spend monitoring qPCR curves now goes to planning experiments, reading papers, and analyzing data, or sometimes just taking a nap and spending an hour in the sun.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;These demonstrations are still just proofs-of-concept. More complicated experimental protocols will require significant optimization to work reliably, as well as the integration of broader and more complex physical manipulations. Running an agent continuously over long monitoring windows also has compute costs that need to be weighed against the researcher time saved.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;These considerations aside, we are excited to continue to experiment with how MHS might help us run a fully autonomous design-build-test-learn round. Every round of&lt;em&gt; de novo &lt;/em&gt;protein design or optimization currently stalls at the handoffs, where I carry results from one stage to the next; in the future, with MHS giving an agent a stable interface into every instrument, that cycle could run on its own. I can envision an agent proposing a set of designs, running the builds and assays, reading the results back through that same interface, and using what it learns to plan the next round. A lab that can generate its own scientific data in this way, round after round, is beginning to look reachable, even on an academic budget.&lt;/p&gt;&lt;h4 class=&quot;headline-6&quot;&gt;Acknowledgements&lt;/h4&gt;&lt;p class=&quot;body-2 serif&quot;&gt;We thank peer reviewer Pushya Krishna as well as Xander Balwit, Rebecca Hiscott, Ethan Dyer, Conor Kelly, and Siddharth Mishra-Sharma for providing helpful feedback. We are grateful to Alek Kemeny and Bailey Bova for helping us set up MHS. Special thanks to Dr. Sudarshan Pinglay for his contributions, support, and guidance on the blog, and for Dr. David Baker’s mentorship in my research.&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/footer&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item bg-ivory-medium&quot;&gt;&lt;h3 class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-title headline-6&quot;&gt;Carnegie Mellon University: Determining dose-response curves through rapid automation&lt;/h3&gt;&lt;div class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-overview body-3&quot;&gt;&lt;p class=&quot;body-2 serif body-2&quot;&gt;&lt;em&gt;Researchers at Carnegie Mellon University used MHS to run serial dilution dose-response experiments about three times faster than before, with an AI agent orchestrating a liquid handler, a plate reader, a robotic arm, and monitoring cameras spread across three computers with fundamentally incompatible interfaces.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;footer class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-footer&quot;&gt;&lt;button class=&quot;Button-module-scss-module__f9ZZrG__button Button-module-scss-module__f9ZZrG__small Button-module-scss-module__f9ZZrG__tertiary Button-module-scss-module__f9ZZrG__iconRight&quot; 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aria-label=&quot;Close&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;20&quot; height=&quot;20&quot; viewBox=&quot;0 0 20 20&quot;&gt;&lt;path transform=&quot;translate(3.7, 3.7)&quot; d=&quot;M0.45 0C0.698528 1.25348e-08 0.9 0.201472 0.9 0.45V12.15L0.891211 12.2405C0.849337 12.4457 0.667542 12.6 0.45 12.6C0.232458 12.6 0.0506628 12.4457 0.00878906 12.2405L0 12.15V0.45C1.25348e-08 0.201472 0.201472 -2.68736e-10 0.45 0ZM7.42236 1.86152C7.60284 1.75552 7.83937 1.78693 7.98486 1.94854C8.1304 2.11024 8.13662 2.34881 8.01211 2.51719L7.95147 2.58486L4.32334 5.85H12.15C12.3985 5.85 12.6 6.05147 12.6 6.3C12.6 6.54853 12.3985 6.75 12.15 6.75H4.32334L7.95147 10.0151C8.13615 10.1814 8.15111 10.4668 7.98486 10.6515C7.8186 10.8361 7.53325 10.8511 7.34854 10.6849L2.84854 6.63486L2.78525 6.56455C2.73 6.48837 2.7 6.3957 2.7 6.3C2.7 6.17245 2.75374 6.05047 2.84854 5.96514L7.34854 1.91514L7.42236 1.86152Z&quot; fill=&quot;#5E5D59&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/button&gt;&lt;/header&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-body body-2&quot;&gt;&lt;section class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study&quot;&gt;&lt;h3 class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-header headline-4&quot;&gt;Carnegie Mellon University: Determining dose-response curves through rapid automation&lt;/h3&gt;&lt;div class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-overview body-2 serif&quot;&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;em&gt;Researchers at Carnegie Mellon University used MHS to run serial dilution dose-response experiments about three times faster than before, with an AI agent orchestrating a liquid handler, a plate reader, a robotic arm, and monitoring cameras spread across three computers with fundamentally incompatible interfaces.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;div class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-media&quot;&gt;&lt;video autoplay=&quot;&quot; controls=&quot;&quot; playsinline=&quot;&quot; muted=&quot;&quot; src=&quot;https://cdn.sanity.io/files/4zrzovbb/website/0b1b6ca4c78d207af4d8191e193616df2b2dabdd.mp4&quot;&gt;&lt;/video&gt;&lt;/div&gt;&lt;/section&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;em&gt;Sina Barazandeh, Arth Banka, Gün Kaynar, Jiayi Li, Peneeta Wojcik, Carl Kingsford, Jose Lugo-Martinez, Joshua Kangas &lt;/em&gt;&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;A key component of drug development is determining dosage. Once we have identified a drug candidate, we need to understand how much of the drug is necessary to be effective—too much can be costly, or even toxic, and too little is ineffective. The appropriate dosage is usually determined through a process known as serial dilution. We start with a strong solution and dilute it by the same ratio each time, using the last dilution to make the next one. For example, mix one part solution with nine parts solvent to get a 10x-diluted sample; take one part of that sample and dilute it again, in the same way, and repeat. Each step lowers the concentration by a fixed amount, giving us an even, predictable range to test.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The process is time-consuming and error-prone, typically requiring multiple iterations to determine the right maximum concentration and the appropriate step size between dilutions. Too high a maximum concentration risks saturation, meaning that the signal maxes out and the curve flattens at the top, so those high doses stop providing any useful information about the response. Too small a step size doesn’t cover a wide enough range; too large a step size skips over the transition region entirely, missing the point at which the response actually changes.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;When done by hand, setting up and conducting a set of serial dilution experiments can take weeks. Already onerous in traditional drug development, this is even more impractical in the high-throughput screening of AI-directed drug development, where the aim is to determine the dosages for numerous candidates at a time. It comes as little surprise, then, that serial dilution experiments are a prime target for robotic laboratory automation.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Unfortunately, setting up such automated experiments is &lt;em&gt;itself&lt;/em&gt; complex and time-consuming. It requires coordinating multiple pieces of experimental equipment across several rounds of experimentation to obtain a usable dose-response curve. Even with access to an automated laboratory (a non-trivial requirement, given the need for multiple automation-compatible instruments and costly integration software), it can take weeks of automation engineering and protocol development to develop a procedure to carry out these experiments.&lt;/p&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Our solution&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;MHS enabled us to run these experiments roughly three times faster by allowing AI to programmatically control several pieces of laboratory equipment. Our system combines a CyBio Felix liquid handler (a robot that moves precise volumes of liquid between wells, tubes, and plates), a Varioskan LUX plate reader (the instrument that measures an optical signal, such as fluorescence, in every well of a microplate), a robotic arm to move 96-well plates, and monitoring cameras with an AI-controlled orchestrator to automatically and dynamically measure dose-response curves.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Individually, each of the components is challenging to control programmatically, requiring a unique interface and specific operation modes. An engineer normally has to learn and hand-code a separate integration for every instrument before they can work together. Using MHS, however, we were able to develop drivers from scratch for each of these instruments and an orchestration layer that lets a Claude Opus 4.8 agent run the full protocol autonomously. This took about eight hours, versus the several weeks a vendor-built setup typically takes.&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1464&quot; height=&quot;1074&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/05e6926e8a2eadae5156b8b4601e0e650a55f27b-1464x1074.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;CMU laboratory instruments. (left) The Analytik Jena CyBio FeliX liquid handler for automated pipetting and liquid-transfer workflows. (right) The Thermo Scientific Varioskan LUX multimode plate reader for microplate-based absorbance, fluorescence, and luminescence measurements.&lt;/figcaption&gt;&lt;/figure&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1466&quot; height=&quot;1076&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/4e42afedb6a8c896d966151945c74bbe3fb052dc-1466x1076.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;CMU laboratory instruments, continued. The Thermo Scientific Spinnaker robotic arm for automated microplate handling and transport (left), with monitoring cameras used to observe plate movement and system operation (center and right).&lt;/figcaption&gt;&lt;/figure&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1466&quot; height=&quot;1076&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/5445017faa35cb3c25fd6b81a610536bfc00c036-1466x1076.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;A 96-well plate arranged as a serial dilution, with the concentration decreasing step by step across the columns from 200 µg/mL to 0.20 µg/mL. This produces a broad, predictable concentration range that can be measured to build a dose-response curve.&lt;/figcaption&gt;&lt;/figure&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Hardware, setup, and workflow&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Our setup uses three computers. Computer 1 runs the robotic arm, controlled through scheduling software that takes job files dropped into a submission directory instead of a normal API. Computer 2 runs the liquid handler through an older Windows ActiveX/COM scripting interface, plus the monitoring cameras over USB. And computer 3 runs the plate reader, which has no programmatic interface at all, only an on-screen GUI. MHS turns each of these into one manifest of states (the conditions a system can be in; for example, plate at position 3, sample at 25°C, well filled) and procedures (the operations it can perform, such as aspirating or shaking), so the model works from a single, consistent interface, no matter which of the three computer control styles is running underneath.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The workflow itself is identical to what it was before MHS, only it’s now agent-driven: the liquid handler prepares a dilution series, a camera check confirms the plate is present and correctly oriented before any transfer is allowed, the arm moves the plate to the reader, the reader takes the measurement, and the model looks at the resulting curve and decides whether to adjust the concentration range and run it again or accept the result. To test it, we used a colorimetric dye (a dye whose color intensity tracks its concentration) as a stand-in for the actual drug candidate. This kept the experiment safe and easy to visualize while still requiring the same decision-making a real dose-response run would need.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Each instrument’s interface brings its own challenges. The arm’s scheduler is based on a directory watcher that generates two different files per submitted XML file, which MHS must reconcile to get one clean result, typically within a second of submission. The liquid handler only exposes COM scripting with no modern SDK, so each usable method had to be worked out either from vendor documentation or from a Claude Opus 4.8 agent exploring the interface to write a functional driver. A single dispense cycle takes about four to five minutes, and the allowed error margin on dispensed volume is only 5% before the resulting curve becomes unusable. The version of the plate reader software we use has no API of any kind, so MHS drives its GUI the same way a person would, with nothing to check its work against except what’s visible on screen.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Before this, a person had to sit through each of these steps: watching the arm’s log for failures, checking that the plate was seated correctly, and deciding whether a resulting curve was informative enough to keep or whether the concentration range needed adjusting and the whole thing needed to be rerun. MHS and the agent now handle all three of these decisions directly and automatically.&lt;/p&gt;&lt;h3 class=&quot;headline-6&quot;&gt;What we have achieved with MHS&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;To verify that MHS would operate safely and correct itself like a human operator would, we artificially induced six different conditions: missing plate, rotated plate, reader busy, disconnected camera, unreachable device, and active emergency stop. The system correctly blocked all six before any device moved. Then we asked the agent to run the serial dilution experiment to achieve an acceptable curve. The model evaluated the resulting curve, but found a fit too poor to accept (R² &amp;lt; 0.9, driven by saturation in the upper concentration range) and decided independently to discard the plate and rerun on a fresh plate with a compressed concentration range (200 µg/mL top concentration reduced to 100 µg/mL). The second run produced a strong, usable fit (R² &amp;gt; 0.98 with 3.4 variation across repeated measurements) with no human input at any point. &lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1639&quot; height=&quot;1019&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/10cf5c1fe1c219338eb7ad8c99fffb70ae2af86e-1639x1019.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;Run 1. The first serial dilution experiment tested concentrations up to 200 µg/mL. At the higher concentrations, the measurement began to saturate, meaning the signal stopped increasing in a useful way. Because this made the dose-response curve less reliable, the system rejected the run and decided that the concentration range needed to be adjusted.&lt;/figcaption&gt;&lt;/figure&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1639&quot; height=&quot;1019&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/3463b88b2a74c3e9111fe1f996e4e58aeca3f45d-1639x1019.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;Run 2. The system automatically repeated the experiment with a lower maximum concentration of 100 µg/mL. This new range captured the changing response much more clearly, producing a stronger and more reliable dose-response curve. The improved fit was accepted without any human intervention.&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The most impressive thing about MHS was the integration speed. The time from raw, non-automated equipment readiness to a completed dilution curve, including one autonomous rerun, was eight hours. By contrast, engaging a vendor to deliver a working automated setup typically takes multiple weeks. The instruments run their own native software as usual; MHS adds an orchestration layer on top, with no additional automation software required. Any device with an API, SDK, or GUI interface can be integrated. The drivers developed for each instrument have been standardized and will be made publicly available, so others can reuse them rather than repeating the integration work from scratch.&lt;/p&gt;&lt;h3 class=&quot;headline-6&quot;&gt;What’s next&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Future work in our lab will focus on validating the system with real drug candidates and replacing the dye’s color signal with readouts that capture actual biological effects. We also plan to expand MHS support to instruments such as qPCR and microscopes, and to integrate MCP-based agents with the MHS fleet. We also hope to reduce the integration time per instrument so we can scale the system for larger workflows.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;We are also making sure this automation can be carried out safely. We plan to add more safety checks, monitor instrument and device responsiveness throughout our experiments, and refine our protocols for when and how human approvals are required for high-risk decisions. We’re looking forward to further exploring how else we can speed up the automation of our experiments, as MHS helps our researchers move faster, safely.&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/footer&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item bg-ivory-medium&quot;&gt;&lt;h3 class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-title headline-6&quot;&gt;HHMI Janelia: Using MHS to accelerate microscopy research&lt;/h3&gt;&lt;div class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-overview body-3&quot;&gt;&lt;p class=&quot;body-2 serif body-2&quot;&gt;&lt;em&gt;At HHMI Janelia Research Campus, researchers are using MHS to speed up a range of microscopy-related projects. Here, Virginie Ruetten, a scientist in the Ahrens lab who studies how sleep helps the body recover from stress, shares how she used MHS to unify and orchestrate a rig that previously involved seven different vendor programs without a shared interface.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;footer class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-footer&quot;&gt;&lt;button class=&quot;Button-module-scss-module__f9ZZrG__button Button-module-scss-module__f9ZZrG__small Button-module-scss-module__f9ZZrG__tertiary Button-module-scss-module__f9ZZrG__iconRight&quot; aria-expanded=&quot;false&quot; aria-haspopup=&quot;dialog&quot;&gt;&lt;span class=&quot;caption&quot;&gt;Read more&lt;/span&gt;&lt;span class=&quot;Button-module-scss-module__f9ZZrG__icon&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon CaseStudyCarousel-module-scss-module__evH4Ta__flyout-trigger-icon&quot; width=&quot;20&quot; height=&quot;20&quot; viewBox=&quot;0 0 20 20&quot;&gt;&lt;path transform=&quot;translate(3.7, 3.7)&quot; d=&quot;M0.45 0C0.698528 1.25348e-08 0.9 0.201472 0.9 0.45V12.15L0.891211 12.2405C0.849337 12.4457 0.667542 12.6 0.45 12.6C0.232458 12.6 0.0506628 12.4457 0.00878906 12.2405L0 12.15V0.45C1.25348e-08 0.201472 0.201472 -2.68736e-10 0.45 0ZM7.42236 1.86152C7.60284 1.75552 7.83937 1.78693 7.98486 1.94854C8.1304 2.11024 8.13662 2.34881 8.01211 2.51719L7.95147 2.58486L4.32334 5.85H12.15C12.3985 5.85 12.6 6.05147 12.6 6.3C12.6 6.54853 12.3985 6.75 12.15 6.75H4.32334L7.95147 10.0151C8.13615 10.1814 8.15111 10.4668 7.98486 10.6515C7.8186 10.8361 7.53325 10.8511 7.34854 10.6849L2.84854 6.63486L2.78525 6.56455C2.73 6.48837 2.7 6.3957 2.7 6.3C2.7 6.17245 2.75374 6.05047 2.84854 5.96514L7.34854 1.91514L7.42236 1.86152Z&quot; fill=&quot;#5E5D59&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/span&gt;&lt;/button&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-root&quot; inert=&quot;&quot; data-theme=&quot;ivory&quot;&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-backdrop&quot; aria-hidden=&quot;true&quot;&gt;&lt;/div&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-panel&quot; role=&quot;dialog&quot; aria-modal=&quot;true&quot; aria-labelledby=&quot;_R_2i669lfiv5vivb_&quot; style=&quot;transform:translateX(100%)&quot;&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-sentinel&quot; aria-hidden=&quot;true&quot;&gt;&lt;/div&gt;&lt;header class=&quot;Flyout-module-scss-module__XIkMnq__flyout-header&quot;&gt;&lt;h2 id=&quot;_R_2i669lfiv5vivb_&quot; class=&quot;Flyout-module-scss-module__XIkMnq__flyout-title caption&quot;&gt;HHMI Janelia&lt;/h2&gt;&lt;button type=&quot;button&quot; class=&quot;Flyout-module-scss-module__XIkMnq__flyout-close&quot; aria-label=&quot;Close&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;20&quot; height=&quot;20&quot; viewBox=&quot;0 0 20 20&quot;&gt;&lt;path transform=&quot;translate(3.7, 3.7)&quot; d=&quot;M0.45 0C0.698528 1.25348e-08 0.9 0.201472 0.9 0.45V12.15L0.891211 12.2405C0.849337 12.4457 0.667542 12.6 0.45 12.6C0.232458 12.6 0.0506628 12.4457 0.00878906 12.2405L0 12.15V0.45C1.25348e-08 0.201472 0.201472 -2.68736e-10 0.45 0ZM7.42236 1.86152C7.60284 1.75552 7.83937 1.78693 7.98486 1.94854C8.1304 2.11024 8.13662 2.34881 8.01211 2.51719L7.95147 2.58486L4.32334 5.85H12.15C12.3985 5.85 12.6 6.05147 12.6 6.3C12.6 6.54853 12.3985 6.75 12.15 6.75H4.32334L7.95147 10.0151C8.13615 10.1814 8.15111 10.4668 7.98486 10.6515C7.8186 10.8361 7.53325 10.8511 7.34854 10.6849L2.84854 6.63486L2.78525 6.56455C2.73 6.48837 2.7 6.3957 2.7 6.3C2.7 6.17245 2.75374 6.05047 2.84854 5.96514L7.34854 1.91514L7.42236 1.86152Z&quot; fill=&quot;#5E5D59&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/button&gt;&lt;/header&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-body body-2&quot;&gt;&lt;section class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study&quot;&gt;&lt;h3 class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-header headline-4&quot;&gt;HHMI Janelia: Using MHS to accelerate microscopy research&lt;/h3&gt;&lt;div class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-overview body-2 serif&quot;&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;em&gt;At HHMI Janelia Research Campus, researchers are using MHS to speed up a range of microscopy-related projects. Here, Virginie Ruetten, a scientist in the Ahrens lab who studies how sleep helps the body recover from stress, shares how she used MHS to unify and orchestrate a rig that previously involved seven different vendor programs without a shared interface.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;/section&gt;&lt;p class=&quot;body-2 serif&quot;&gt;A few nights of disrupted sleep are enough to cause widespread impairment: altered cognition, dysregulated metabolism, a weakened immune system. If this goes on long enough, sleep loss can even prove fatal. Yet we still don’t fully understand why. Part of the reason sleep is so hard to study is that it isn’t localized to any one organ. Because sleep is a whole-animal state, developing a mechanistic understanding of it requires measuring many parts of the body at once.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Microscopy offers a way to do this. Cells engineered to express fluorescent sensors emit light that signals their activity; microscopes can image these signals with high temporal and spatial resolution, letting us observe what these cells are doing. However, most animals are too large or too opaque for such imaging to function across the body. My work thus uses young zebrafish. This model organism is popular for its small size and transparency, and its organs and many aspects of its sleep physiology are similar to those of mammals, including humans.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;These properties, combined with an experimental approach I developed called &lt;a href=&quot;https://wholistic.janelia.org/&quot; target=&quot;_blank&quot; rel=&quot;noopener&quot;&gt;WHOLISTIC imaging&lt;/a&gt;, allow us to use two-photon microscopy to capture cellular activity throughout the brain and body of a living zebrafish. Rather than taking snapshots of isolated tissues, we can watch how cells and organs respond and interact from moment to moment across the entire animal, giving us a better understanding of the cellular players and underlying mechanisms behind physiological processes.&lt;/p&gt;&lt;figure&gt;&lt;video autoplay=&quot;&quot; controls=&quot;&quot; playsinline=&quot;&quot; muted=&quot;&quot; src=&quot;https://cdn.sanity.io/files/4zrzovbb/website/7104f46b19b038fefbaa382d8f1f2be4d4a6a850.mp4&quot;&gt;&lt;/video&gt;&lt;figcaption class=&quot;caption&quot;&gt;WHOLISTIC imaging of body-wide cellular activity in a larval zebrafish seven days post-fertilization. Maximum-intensity projection through the full volume of a young fish expressing the calcium indicator GCaMP7f in all cells, imaged with a customized mesoscope, a two-photon large field of view microscope. Fluorescence transients report intracellular calcium, a proxy for cellular activity, and are visible simultaneously in the brain, spinal cord, heart, gut, and peripheral tissue.&lt;/figcaption&gt;&lt;/figure&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Controlling and coordinating devices through a unified interface&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The instruments needed to carry out my experiments fill an entire room. As is common in many advanced microscopy setups, my rig is cobbled together from many components, each of which has been bought separately, from a different manufacturer, and wired up by hand: powerful femtosecond lasers; fast galvanometer mirrors, which sweep the microscope’s laser beam across the sample; super-sensitive photomultiplier detectors, which collect the returning light; and two precise translation stages, which position the fish relative to the sample holder, and the sample holder relative to the microscope.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;These devices have to operate on a tight, shared schedule: the laser must be gated in step with the mirrors that scan it, and the stage must compensate if the animal moves or the sample drifts out of the focal plane. However, these devices were not designed to work together. Each comes with its own vendor control software, with no common interface. They often run in different programming languages, too: the detectors run in MATLAB, the cameras in Python, the electrophysiology in C#. A quantity held by one program, such as the position of the stage, is therefore unknown to the others. Yet the devices need to communicate—for example, each stage needs to know the other’s location for the system to know the absolute location of the sample.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The consequence of this incompatibility is that I spend a lot of time figuring out how to get devices to talk to each other, writing bespoke code to bridge two programs—or, in some cases, resorting to adding yet another device, a digital acquisition board (DAQ), a card that physically routes and transforms electrical signals, so the devices can communicate. Once everything is wired up, I still need to launch seven programs in a fixed order just to start an experiment, an error-prone process where getting the launch order wrong can cost the whole session.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;MHS replaces those point-to-point connections with a single interface. Each device is now described and onboarded once, and its variables, controls, and sensor values are recorded in a single dictionary that lives in shared memory, a region of the computer’s memory that the operating system lets many programs access.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The benefit is that the cost of hardware integration stops scaling with the number of devices. Before MHS, integrating new pieces of hardware into the system was a multi-day project. Since implementing it, however, when I added a new camera to image the laser beam, it took me only a few minutes, and I could seamlessly feed the camera’s output—the location of the beam—back to the mirrors steering the beam, allowing me to more precisely align it. Starting an experiment now involves one click on the MHS dashboard instead of seven separate steps.&lt;/p&gt;&lt;figure&gt;&lt;video autoplay=&quot;&quot; controls=&quot;&quot; playsinline=&quot;&quot; muted=&quot;&quot; src=&quot;https://cdn.sanity.io/files/4zrzovbb/website/af084a36feacb3714d57e84c79c5750010da1b40.mp4&quot;&gt;&lt;/video&gt;&lt;figcaption class=&quot;caption&quot;&gt;Beam alignment using MHS. Data from a laser beam camera streams through the MHS state dictionary. A digital target (white cross) can be added to guide alignment, and the beam can be precisely centered manually or using motorized mirrors controlled by an agent.&lt;/figcaption&gt;&lt;/figure&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Quantitative monitoring and online analysis&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Even after the hardware is wired up, I still need to run a plethora of checks and parameter adjustments before and during experiments to ensure I’m acquiring high-quality data. This includes monitoring the fish’s health, ensuring the camera is focused on the heart to measure heart rate variability, and surveying the quality of the fluorescence image to ensure that the cells I want to record are visible at high resolution. Each check involves computing a derived quantity from one of the many data streams the rig produces, such as the signal-to-noise ratio of the fluorescence data or the fish’s heart rate.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Such quantitative monitoring used to be laborious, as each data stream was collected by a separate program, and the values each program held in memory could not be easily read by any other program while the recording ran. Before MHS, I had three options, none of them optimal. First, I could collect the data and analyze it afterward, iterating on parameters between runs once it was saved to disc. But this took hours, and sometimes ended with the discovery that the recording was unusable. Second, I could judge the data by eye in the vendor viewer. This was fast, but it only gives an impression, not a precise measurement that can be compared across runs. Third, I could bolt analysis code onto the program doing the recording. But this was a pain because the code had to be rewritten for every program producing a data stream. Displaying the data streams was similarly time-consuming, because each application needed its own bespoke viewer, written in whatever language the recording program used.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;MHS unified that fragmented process and removes the per-program rewrite. With MHS, each data stream is stored in shared memory in the MHS state dictionary, in a documented format that is readable by any process that attaches to it. Because each data stream is presented in the same way, analysis or visualization code can now be reused across devices and written in any language.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;This allowed me to write a modular online analysis framework that guides the data through a chain of processing steps: data enters from a slot (an entry in the MHS state dictionary), passes through reusable transforms (operations on the data), and the result is written back to another slot or to disk. For visualization, I wrote a set of viewers—one per data type, rather than one per device—for images, time series, spectra, etc. Now, any data stream can be inspected while it’s being acquired, and I don’t need to rewrite any code to inspect a new one. When I became interested in how the zebrafish’s heart rate changes across the sleep-wake cycle, I could add a transform to compute the spectral content of the heart activity, as recorded by a camera, to estimate its heart rate; I could then reuse the code to compute the spectrum of the concurrent neural activity acquired by a different device, in a different language. Effort now compounds in one codebase rather than being split across one per device.&lt;/p&gt;&lt;figure&gt;&lt;video autoplay=&quot;&quot; controls=&quot;&quot; playsinline=&quot;&quot; muted=&quot;&quot; src=&quot;https://cdn.sanity.io/files/4zrzovbb/website/04157144975f52a1e0d9ae8618b04947d51769e5.mp4&quot;&gt;&lt;/video&gt;&lt;figcaption class=&quot;caption&quot;&gt;Online heartbeat tracking and prediction using MHS. Data from a camera imaging the ventral side of the animal is streamed through MHS, where it can be monitored using a generic MHS array slot viewer. Once in the MHS state dictionary, the data is instantly accessible to other processes, allowing for online identification of the heart and real-time tracking of heart activity (blue curve). Another process fits a predictive model enabling phase-locked stimulation (orange curve).&lt;/figcaption&gt;&lt;/figure&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Running smarter experiments with agents&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Experiments always involve tradeoffs. In imaging, for instance, I have to trade speed against coverage: I can scan a single plane—one thin optical slice through the brain—quickly, or many planes, to cover more of the brain, slowly. Finding the cells with the oscillatory activity I care about requires coverage, but measuring that activity requires speed.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Today, most experiments are ballistic: I select one set of settings at the start, one condition, and launch the run. So I have to pick a point on that tradeoff before the data tells me which point I need. Experiments last hours, so staying at the rig throughout is impractical—and biology is too variable and messy to have a simple deterministic algorithm do the searching for me. Ideally, I wouldn’t have to trade one for the other; I’d be able to search broadly, find the population of cells with the oscillatory activity I care about, then sample that precise region fast enough to resolve phase relationships between cells.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Agentic microscopy is the obvious way to get there: let an agent identify a region of interest and zoom in on it. But historically, that’s been easier said than done. The hard part isn’t getting the agent to iterate on writing analysis code to figure out where to zoom; it&#39;s getting it to reliably control a rig where commands move real devices, and where failure means a crashed objective, or an agent losing the few hours the sample preparation holds to the quirks of half a dozen vendor programs.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;This is where I found MHS particularly helpful. With the entire rig’s state in a shared, standardized dictionary, agents can read and write every variable through a single interface, instead of seven vendor APIs, which removes the failure modes specific to each of them. I wrote a simple harness that made my rig operable by an AI agent. The core deterministic loop iterates between acquisition and analysis, and each result feeds the next decision. The agent enters at decision points, choosing the acquisition parameters (for example, what region to image) and what analysis to run, online and offline, in service of a user-stated goal. And because MHS enforces device-level safety limits, I don’t need to worry about the agent accidentally using excess laser power, for example, which risks bleaching the fluorescent molecules and degrading the sample. I&#39;m still developing the framework and supervising experiments, but it has already allowed me to find the oscillatory population that a fixed setting would have missed, so I need fewer repeat runs and fewer animals to get the same number of usable recordings.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Going forward, I want to understand how these oscillations in the brain contribute to sleep and arousal so that my colleagues and I can identify targets for drugs that deliver restorative sleep, not just sedation. This requires mapping which cells are coupled to the oscillation, then running perturbation experiments phase-locked to it, to uncover the mechanism by which these cells shape global brain state. Doing this involves fitting models to the activity of thousands of cells as the data streams in, then triggering light-based activation of specific neurons—a technique called optogenetics—while the recording is running.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Such closed-loop experiments are hard because of the need to coordinate so many devices at speed, on a rig assembled from several vendors’ hardware that share no low-latency interface. MHS supplies the speed and adaptability, while still being easy for both humans and agents to comprehend. It doesn’t dispense with the tradeoffs that come with cellular activity imaging—such as speed versus coverage or how bright the signal is versus how long it lasts—since those are set by physics. But it does change how quickly I can explore the parameter space, home in on the right set, and iterate through experimental conditions and hypotheses. With MHS, I now look forward to the day when hardware control no longer limits the questions I can ask.&lt;/p&gt;&lt;figure&gt;&lt;video autoplay=&quot;&quot; controls=&quot;&quot; playsinline=&quot;&quot; muted=&quot;&quot; src=&quot;https://cdn.sanity.io/files/4zrzovbb/website/114e1e623740cf010903446523b8248f0088a2bc.mp4&quot;&gt;&lt;/video&gt;&lt;figcaption class=&quot;caption&quot;&gt;Online neural activity monitoring using MHS. Data from the two-photon microscope, imaging the hindbrain of a fish, is streamed to MHS, making it instantly accessible to other processes. The researcher can define regions of interest to monitor live activity (top trace: muscle; bottom trace: neuronal population), which is then fed back to an MHS slot, making it accessible for downstream processing.&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;br&gt;&lt;em&gt;Virginie Ruetten’s is just one of a handful of projects incorporating MHS at Janelia. Another team, led by Arco Bast in the Spruston lab, images neurons and their dendrites deep in the brains of living mice as they learn to navigate a virtual environment, watching memories form in real time. MHS grew out of Arco’s idea of putting the entire rig’s state in a standardized dictionary in shared memory, and his custom microscope was the first rig to run on it. Every laser, mirror, and sensor in his rig is exposed through MHS, so Claude can align the beams, tune the optics, and check its own results against the sensors, turning a half-day of manual setup into a single step. Another team, co-led by Magdalena Schneider and Hari Shroff, is using MHS to enable &lt;a href=&quot;https://github.com/gently-project/gently&quot; target=&quot;_blank&quot; rel=&quot;noopener&quot;&gt;agentic control&lt;/a&gt; of a light-sheet microscope. This allows Claude to act as an orchestrator, deciding in real time how to image developing C. elegans embryos, and how to make trade-offs between competing imaging parameters. Across all projects, MHS has helped the researcher compress integration times, and made it possible for AI agents to control complex combinations of instruments, data visualization, and analysis, paving the way for faster discovery across a range of domains.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/footer&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item bg-ivory-medium&quot;&gt;&lt;h3 class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-title headline-6&quot;&gt;QuEra Computing: Using MHS in quantum laser stabilization&lt;/h3&gt;&lt;div class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-overview body-3&quot;&gt;&lt;p class=&quot;body-2 serif body-2&quot;&gt;&lt;em&gt;QuEra, a company that builds quantum computers using neutral atoms, used MHS to give an AI agent control over parts of the laser system inside its quantum machines. The agent developed a controller that recovers the laser’s “lock”—the ultra-precise frequency the lasers must hold to interact with the atoms—99.3% of the time without human intervention.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;footer class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-footer&quot;&gt;&lt;button class=&quot;Button-module-scss-module__f9ZZrG__button Button-module-scss-module__f9ZZrG__small Button-module-scss-module__f9ZZrG__tertiary Button-module-scss-module__f9ZZrG__iconRight&quot; aria-expanded=&quot;false&quot; aria-haspopup=&quot;dialog&quot;&gt;&lt;span class=&quot;caption&quot;&gt;Read more&lt;/span&gt;&lt;span class=&quot;Button-module-scss-module__f9ZZrG__icon&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon CaseStudyCarousel-module-scss-module__evH4Ta__flyout-trigger-icon&quot; width=&quot;20&quot; height=&quot;20&quot; viewBox=&quot;0 0 20 20&quot;&gt;&lt;path transform=&quot;translate(3.7, 3.7)&quot; d=&quot;M0.45 0C0.698528 1.25348e-08 0.9 0.201472 0.9 0.45V12.15L0.891211 12.2405C0.849337 12.4457 0.667542 12.6 0.45 12.6C0.232458 12.6 0.0506628 12.4457 0.00878906 12.2405L0 12.15V0.45C1.25348e-08 0.201472 0.201472 -2.68736e-10 0.45 0ZM7.42236 1.86152C7.60284 1.75552 7.83937 1.78693 7.98486 1.94854C8.1304 2.11024 8.13662 2.34881 8.01211 2.51719L7.95147 2.58486L4.32334 5.85H12.15C12.3985 5.85 12.6 6.05147 12.6 6.3C12.6 6.54853 12.3985 6.75 12.15 6.75H4.32334L7.95147 10.0151C8.13615 10.1814 8.15111 10.4668 7.98486 10.6515C7.8186 10.8361 7.53325 10.8511 7.34854 10.6849L2.84854 6.63486L2.78525 6.56455C2.73 6.48837 2.7 6.3957 2.7 6.3C2.7 6.17245 2.75374 6.05047 2.84854 5.96514L7.34854 1.91514L7.42236 1.86152Z&quot; fill=&quot;#5E5D59&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/span&gt;&lt;/button&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-root&quot; inert=&quot;&quot; data-theme=&quot;ivory&quot;&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-backdrop&quot; aria-hidden=&quot;true&quot;&gt;&lt;/div&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-panel&quot; role=&quot;dialog&quot; aria-modal=&quot;true&quot; aria-labelledby=&quot;_R_2im69lfiv5vivb_&quot; style=&quot;transform:translateX(100%)&quot;&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-sentinel&quot; aria-hidden=&quot;true&quot;&gt;&lt;/div&gt;&lt;header class=&quot;Flyout-module-scss-module__XIkMnq__flyout-header&quot;&gt;&lt;h2 id=&quot;_R_2im69lfiv5vivb_&quot; class=&quot;Flyout-module-scss-module__XIkMnq__flyout-title caption&quot;&gt;QuEra Computing&lt;/h2&gt;&lt;button type=&quot;button&quot; class=&quot;Flyout-module-scss-module__XIkMnq__flyout-close&quot; aria-label=&quot;Close&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;20&quot; height=&quot;20&quot; viewBox=&quot;0 0 20 20&quot;&gt;&lt;path transform=&quot;translate(3.7, 3.7)&quot; d=&quot;M0.45 0C0.698528 1.25348e-08 0.9 0.201472 0.9 0.45V12.15L0.891211 12.2405C0.849337 12.4457 0.667542 12.6 0.45 12.6C0.232458 12.6 0.0506628 12.4457 0.00878906 12.2405L0 12.15V0.45C1.25348e-08 0.201472 0.201472 -2.68736e-10 0.45 0ZM7.42236 1.86152C7.60284 1.75552 7.83937 1.78693 7.98486 1.94854C8.1304 2.11024 8.13662 2.34881 8.01211 2.51719L7.95147 2.58486L4.32334 5.85H12.15C12.3985 5.85 12.6 6.05147 12.6 6.3C12.6 6.54853 12.3985 6.75 12.15 6.75H4.32334L7.95147 10.0151C8.13615 10.1814 8.15111 10.4668 7.98486 10.6515C7.8186 10.8361 7.53325 10.8511 7.34854 10.6849L2.84854 6.63486L2.78525 6.56455C2.73 6.48837 2.7 6.3957 2.7 6.3C2.7 6.17245 2.75374 6.05047 2.84854 5.96514L7.34854 1.91514L7.42236 1.86152Z&quot; fill=&quot;#5E5D59&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/button&gt;&lt;/header&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-body body-2&quot;&gt;&lt;section class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study&quot;&gt;&lt;h3 class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-header headline-4&quot;&gt;QuEra Computing: Using MHS in quantum laser stabilization&lt;/h3&gt;&lt;div class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-overview body-2 serif&quot;&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;em&gt;QuEra, a company that builds quantum computers using neutral atoms, used MHS to give an AI agent control over parts of the laser system inside its quantum machines. The agent developed a controller that recovers the laser’s “lock”—the ultra-precise frequency the lasers must hold to interact with the atoms—99.3% of the time without human intervention.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;/section&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The promise of quantum computing lies in its ability to harness the properties of quantum mechanics to perform calculations that are out of reach of even the largest supercomputers. QuEra’s neutral-atom approach uses the naturally occurring quantum mechanics observable in a single atom as the foundation for these calculations. Nearly all aspects of the control, operation, and readout of these atomic qubits—the quantum bits that hold the computer’s information—are done through the controlled interaction of a laser with atoms.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;For that to work, each laser has to hold its color (its frequency, measured in Hz) to an astonishing precision, roughly one part in a trillion. That’s equivalent to measuring the distance from the Earth to the Moon to within the width of a human hair. Physicists call a laser “locked” when its frequency is held this tightly. Everyday disturbances, such as temperature, vibration, or a shift in pressure, can push the laser off the desired frequency and “unlock” it, causing quantum operations to start to fail. As quantum computers perform long, error-corrected programs, a laser that ends up off its target frequency mid-run can spoil a computation that took hours to build up.&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;eager&quot; width=&quot;1819&quot; height=&quot;1366&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/39ae2db437d11a494bc8da516b4150a542b391ee-1819x1366.jpg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;strong&gt;Figure 1&lt;/strong&gt;. Part of the optical path that delivers laser light to the atoms.&lt;/figcaption&gt;&lt;/figure&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;eager&quot; width=&quot;2048&quot; height=&quot;1366&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/237bb6752e0e00a1057605f295574464d0fe67a8-2048x1366.jpg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;strong&gt;Figure 2&lt;/strong&gt;. The vacuum chamber where the atoms are held, inside the glass cell at center.&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The laser at the center of this work is a titanium-sapphire laser, a tunable workhorse that atomic physics and quantum technology have relied on for more than 20 years. Traditionally, these lasers were controlled by hand, tuned for one-off experiments by experts. In QuEra’s quantum computers, those experts are aided by software that can detect and correct the most common disturbances before the lock is lost. But the potential sources of failure are so dynamic and varied that they cannot all be planned for in advance, so new or uncommon failures still need expert intervention. That requires an experienced operator, who must watch several instruments at once and judge what moved, what to correct, in which order, and when to trust the result. It typically takes 5 to 10 minutes to recover the frequency.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;In university labs, this skill is handed down from one graduate student to the next, and when the lock drops at 2 am, someone has to wake up and drive in to perform the recovery. For a university lab, that is an inconvenience and an inefficiency. At the fleet scale of a quantum-computing company, it is simply untenable to keep this skill set in the hands of just a few people.&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1760&quot; height=&quot;790&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/2a5e4365820413ed405e122bfefb15d711f793d6-1760x790.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;strong&gt;Figure 3&lt;/strong&gt;. The laser system, and how Claude reaches it through MHS.&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Given the vast and variable problem space, the complexity of the hardware to be controlled, and how critical this laser system is to the operation of the quantum computer, the team at QuEra identified automated laser recovery as a good first test case for MHS (Figure 3).&lt;/p&gt;&lt;h3 class=&quot;headline-6&quot;&gt;What we achieved with MHS&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Making laser recovery automatic was not a new idea at QuEra. Before MHS, a team comprising a laser-systems engineer, a software engineer, an algorithms specialist, and a tester spent several months building a bespoke script to automate it. That recovery script reproduced what a human does at the bench, step for step: disarm the function holding the lock, work through the laser’s tuning controls in order, check the frequency after each tune, start over if the frequency is still off, and reengage the lock once it’s correct. But it only worked about 58% of the time, and it took around 150 seconds per attempt.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Because the script automates exactly what an expert does, it also inherits the same shortcomings. A linear sequence cannot absorb a change midway through, so when a shift in temperature or air pressure (for example, from somebody opening the door to the lab) undoes a step that had already succeeded, the recovery procedure must start over. This is the case both for an engineer at the bench and for the script, which is part of why a human recovery takes 5 to 10 minutes. Automating the steps made the sequence faster, but not fast enough to outrun the disturbances. This explains both the 150 seconds per attempt and the 42% failure rate.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;QuEra handed the same problem to Claude through MHS. The team began by populating the agent’s context with a goal—write a standalone Python script to relock the laser—and a definition of success—relock on the first attempt, then hold for 30 seconds. The first time we attempted this, it took a day or two; now it only takes a few hours. We then induced disturbances for the agent to recover from: blocking the beam, cutting power to instruments to imitate a surge, and pushing the frequency off target by varying amounts. MHS supplied the access to Claude so it could read the instruments and move the controls as a human operator would.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Having set that up, the agent loop ran as four roles, each a fresh instance of Claude. One proposed a hypothesis for making recovery faster or more reliable; one wrote that change into the recovery script; one ran the updated script against the live laser and logged every step; and another read the logbook and decided what to change next (Figure 4). That cycle repeated hundreds of times, unattended, throughout the night, with each pass iteratively improving the script. By morning, recovery was taking about six seconds and working 96% of the time, against the 150 seconds and 58% it started from (Figure 5).&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1999&quot; height=&quot;579&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/dda6aafac49e58398902d6695015676221bd6377-1999x579.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;strong&gt;Figure 4.&lt;/strong&gt; The loop the agent ran overnight.&lt;/figcaption&gt;&lt;/figure&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1740&quot; height=&quot;884&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/19160a0d4e45918d4b2a0e60389c829640fae6e7-1740x884.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;strong&gt;Figure 5.&lt;/strong&gt; Converging overnight. The 96% success rate shown here is from the development run; the 99.3% reported in the text is from the later blind test.&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;This improvement was the result of Claude rewriting that linear sequence as a decision tree. Instead of one path for every disturbance, the script it converged on reads each instrument, builds up if-then conditions from what the instruments show, and makes adjustments based on the specific physical disturbance and the pattern Claude learned from encountering it repeatedly. For example, if the frequency has barely moved, most of the laser’s controls will not change anything, so the script touches only one or two, leaving the rest alone. A human operator would still have to work through all of them, because the only way to be sure a control is right is to check it. Claude found the shortcut by running disturbances over and over again until the pattern in the lock’s behavior became clear. Claude’s advantage was its ability to do this exceedingly quickly, at a pace no operator could match.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;We then tested the finished script against the same randomized set of induced disturbances with no agent involved. Across 700 trials, it recovered the correct lock 695 times, a 99.3% success rate. The hardest disturbances, where the frequency had hopped far from target, took 10 to 14 seconds, compared to the 5 to 10 minutes for a human at the bench, and the simpler ones took 0.9 to 5.4 seconds (Figure 5). The end product was a deterministic, fully inspectable script capable of running in production without an AI agent controlling it.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;With the laser locking working significantly better, we then pointed the agent at the quality of the lock—that is, how often it unlocks. That’s set by 12 interdependent parameters (known as PID) inside the servo loop (shown in Figure 3). Tuning them well strips residual noise out of the lock, which sharpens the computer’s gates and makes unlocks rarer. Measuring that noise precisely requires capturing an oscilloscope trace and running a Fourier transform on it, which is not realistic for a human after every small change across 12 parameters. Instead, a specialist generally tunes against the root mean square (RMS) error the servo reports, which is a good enough approximation for lock quality. The PID parameters drift with temperature and pressure changes, so the goal is a tune that is good enough to hold for a while, followed by a retune when the lock starts slipping. The video below shows what just three of those parameters do.&lt;/p&gt;&lt;figure&gt;&lt;video autoplay=&quot;&quot; controls=&quot;&quot; playsinline=&quot;&quot; muted=&quot;&quot; src=&quot;https://cdn.sanity.io/files/4zrzovbb/website/1541e894a040db490eac45bf62e65c023d4e90b8.mp4&quot;&gt;&lt;/video&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;strong&gt;Figure 6&lt;/strong&gt;. What tuning entails for three of the 12 parameters. The video cycles through settings that overshoot, undershoot, and land.&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The team pointed Claude at that same RMS number, but after every single adjustment it also captured a trace and computed the full spectrum hundreds of times over the course of the night. That is the part a human cannot match. Minimizing the RMS error usually&lt;em&gt; does &lt;/em&gt;produce the lowest noise across the whole band, and a specialist who has done it for years is typically correct to trust it. But Claude did not have to trust it; instead, it could confirm the &lt;em&gt;exact&lt;/em&gt; amount of residual noise after every change, and keep scouring through the search space until it could guarantee it had found the lowest realistic noise possible.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The laser’s parameters had already been set by a QuEra specialist, and that standing tune measured 15.7 mV of residual error. Over 363 experiments and 16 unattended hours, Claude brought it to 1.55 mV, roughly t10 times quieter on the RMS measure it was optimizing against (Figure 7). To verify that independently, the specialist retuned the same laser from scratch by his usual method, without seeing what Claude had found, and both sets of parameters went to a phase noise analyzer—a rare, specialized instrument used to measure absolute phase noise ( how much fluctuation is present at every frequency). This check also served as a way to fairly compare each PID parameter set. The agent’s tune matched the specialist’s across the band, with one exception: a roughly 220 kHz resonance where the manual tune had left about a thousand times more noise than Claude’s—exactly the kind of error that can occur when using the RMS heuristic, and what Claude’s method was able to avoid). The final check was the one that matters most in practice: how long each tune holds. Over a 19-hour run, Claude’s PIDs did not lose the lock once, while the expert tuned PIDs unlocked about 1.6 times an hour. Unlike the relock controller, this tuning workflow keeps the agent in the loop to adjust the parameters as conditions change.&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1999&quot; height=&quot;950&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/ab799d33fbe3f367a71444f32b142c43e3dc22e2-1999x950.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;strong&gt;Figure 7.&lt;/strong&gt; The tuning run. Each dot represents a setting the agent tried out. The blue line shows the best overall result at each point in the experiment.&lt;/figcaption&gt;&lt;/figure&gt;&lt;h3 class=&quot;headline-6&quot;&gt;What’s next&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;The relock controller was built for a single laser system. But a quantum computer holds many laser systems with similar potential points of failure—not to mention many other subsystems that serve different functions but are similarly precise, fragile, and complex, and which require the same meticulous attention from a scant pool of experts.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;In the pilot, MHS and AI agents did not replace such expertise completely. During the experiments, if something went wrong with the physical hardware, Claude didn’t know how to troubleshoot, as its understanding of the rig was programmatic rather than physical. Claude also often stopped to wait for human confirmation before performing an action it deemed even slightly risky, meaning experiments would sometimes pause overnight while Claude waited for approval. Still, an overly cautious agent is preferable to one that is not cautious enough. Finally, the team needed to provide a ton of context to Claude about what they wanted from the experiment and how Claude should carry it out for it to perform the tasks correctly.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Even with these limitations, the pilot showed that an AI agent can meaningfully improve how such systems are controlled, and some of these limitations should ease as models become more capable and build up a more sophisticated understanding of hardware. Next, QuEra aims to deploy the relock recovery system on live quantum processors, package the tuning workflow as a standalone tool, and apply the lessons from this experiment to other subsystems—working towards a fleet of machines that increasingly look after themselves.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;em&gt;Read more about the pilot experiment &lt;a href=&quot;http://www.quera.com/blog-posts/holding-the-light-teaching-an-ai-to-lock-and-tune-our-quantum-computers-lasers&quot; target=&quot;_blank&quot; rel=&quot;noopener&quot;&gt;on the QuEra blog&lt;/a&gt;.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/footer&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item bg-ivory-medium&quot;&gt;&lt;h3 class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-title headline-6&quot;&gt;Tetsuwan Scientific: Using MHS to run qPCRs to profile local pollution &lt;/h3&gt;&lt;div class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-overview body-3&quot;&gt;&lt;p class=&quot;body-2 serif body-2&quot;&gt;&lt;em&gt;Researchers at Tetsuwan integrated MHS with its automated biology lab platform, ResearchOS. MHS helped orchestrate a qPCR workflow to contribute to citizen science efforts to characterize pollution in California’s San Pedro Creek.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;footer class=&quot;CaseStudyCarousel-module-scss-module__evH4Ta__case-study-footer&quot;&gt;&lt;button class=&quot;Button-module-scss-module__f9ZZrG__button Button-module-scss-module__f9ZZrG__small Button-module-scss-module__f9ZZrG__tertiary Button-module-scss-module__f9ZZrG__iconRight&quot; aria-expanded=&quot;false&quot; aria-haspopup=&quot;dialog&quot;&gt;&lt;span class=&quot;caption&quot;&gt;Read more&lt;/span&gt;&lt;span class=&quot;Button-module-scss-module__f9ZZrG__icon&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon CaseStudyCarousel-module-scss-module__evH4Ta__flyout-trigger-icon&quot; width=&quot;20&quot; height=&quot;20&quot; viewBox=&quot;0 0 20 20&quot;&gt;&lt;path transform=&quot;translate(3.7, 3.7)&quot; d=&quot;M0.45 0C0.698528 1.25348e-08 0.9 0.201472 0.9 0.45V12.15L0.891211 12.2405C0.849337 12.4457 0.667542 12.6 0.45 12.6C0.232458 12.6 0.0506628 12.4457 0.00878906 12.2405L0 12.15V0.45C1.25348e-08 0.201472 0.201472 -2.68736e-10 0.45 0ZM7.42236 1.86152C7.60284 1.75552 7.83937 1.78693 7.98486 1.94854C8.1304 2.11024 8.13662 2.34881 8.01211 2.51719L7.95147 2.58486L4.32334 5.85H12.15C12.3985 5.85 12.6 6.05147 12.6 6.3C12.6 6.54853 12.3985 6.75 12.15 6.75H4.32334L7.95147 10.0151C8.13615 10.1814 8.15111 10.4668 7.98486 10.6515C7.8186 10.8361 7.53325 10.8511 7.34854 10.6849L2.84854 6.63486L2.78525 6.56455C2.73 6.48837 2.7 6.3957 2.7 6.3C2.7 6.17245 2.75374 6.05047 2.84854 5.96514L7.34854 1.91514L7.42236 1.86152Z&quot; fill=&quot;#5E5D59&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/span&gt;&lt;/button&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-root&quot; inert=&quot;&quot; data-theme=&quot;ivory&quot;&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-backdrop&quot; aria-hidden=&quot;true&quot;&gt;&lt;/div&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-panel&quot; role=&quot;dialog&quot; aria-modal=&quot;true&quot; aria-labelledby=&quot;_R_2j669lfiv5vivb_&quot; style=&quot;transform:translateX(100%)&quot;&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-sentinel&quot; aria-hidden=&quot;true&quot;&gt;&lt;/div&gt;&lt;header class=&quot;Flyout-module-scss-module__XIkMnq__flyout-header&quot;&gt;&lt;h2 id=&quot;_R_2j669lfiv5vivb_&quot; class=&quot;Flyout-module-scss-module__XIkMnq__flyout-title caption&quot;&gt;Tetsuwan Scientific&lt;/h2&gt;&lt;button type=&quot;button&quot; class=&quot;Flyout-module-scss-module__XIkMnq__flyout-close&quot; aria-label=&quot;Close&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;20&quot; height=&quot;20&quot; viewBox=&quot;0 0 20 20&quot;&gt;&lt;path transform=&quot;translate(3.7, 3.7)&quot; d=&quot;M0.45 0C0.698528 1.25348e-08 0.9 0.201472 0.9 0.45V12.15L0.891211 12.2405C0.849337 12.4457 0.667542 12.6 0.45 12.6C0.232458 12.6 0.0506628 12.4457 0.00878906 12.2405L0 12.15V0.45C1.25348e-08 0.201472 0.201472 -2.68736e-10 0.45 0ZM7.42236 1.86152C7.60284 1.75552 7.83937 1.78693 7.98486 1.94854C8.1304 2.11024 8.13662 2.34881 8.01211 2.51719L7.95147 2.58486L4.32334 5.85H12.15C12.3985 5.85 12.6 6.05147 12.6 6.3C12.6 6.54853 12.3985 6.75 12.15 6.75H4.32334L7.95147 10.0151C8.13615 10.1814 8.15111 10.4668 7.98486 10.6515C7.8186 10.8361 7.53325 10.8511 7.34854 10.6849L2.84854 6.63486L2.78525 6.56455C2.73 6.48837 2.7 6.3957 2.7 6.3C2.7 6.17245 2.75374 6.05047 2.84854 5.96514L7.34854 1.91514L7.42236 1.86152Z&quot; fill=&quot;#5E5D59&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/button&gt;&lt;/header&gt;&lt;div class=&quot;Flyout-module-scss-module__XIkMnq__flyout-body body-2&quot;&gt;&lt;section class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study&quot;&gt;&lt;h3 class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-header headline-4&quot;&gt;Tetsuwan Scientific: Using MHS to run qPCRs to profile local pollution &lt;/h3&gt;&lt;div class=&quot;CaseStudyBlock-module-scss-module__-93VvG__case-study-overview body-2 serif&quot;&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;em&gt;Researchers at Tetsuwan integrated MHS with its automated biology lab platform, ResearchOS. MHS helped orchestrate a qPCR workflow to contribute to citizen science efforts to characterize pollution in California’s San Pedro Creek.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;/section&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Since the 1960s, labs have had automated machines that can pipette, seal, shake, move labware, and perform most of the other functions of a biology lab. Yet the majority of biology experimentation remains manual. Part of the reason for this is that most biology experiments are fundamentally dynamic: sample count, plate format, and the number of conditions change between runs, as do the scientific parameters, such as dilution series depth, incubation times, the number of timepoints, and so on.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Translating a single experiment configuration into an automated workflow takes a specialist, known as an automation engineer, weeks or months. So automation only pays off when a configuration is repeated at enormous scale, like in high-throughput screening, where one method is used across a library of hundreds of thousands of compounds. The bulk of experimentation remains manual, inheriting all the potential errors and reproducibility problems that entails. &lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Tetsuwan is building an automated biology lab, available to researchers and agents via an API. Without a way to automate both small- &lt;em&gt;and &lt;/em&gt;large-scale configurations, our lab would be confined to the limited capabilities of lab automation today. We built ResearchOS to solve this. ResearchOS is an automation platform that allows users to generate, run, and manage automated workflows without prior lab automation experience within minutes. Claude works with users to turn natural-language protocols into a script written in our syntax for experiments, which is ultimately processed by a custom compiler into automation code.&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;eager&quot; width=&quot;1999&quot; height=&quot;1125&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/a0cae51381c559f791e44aa254a251b2422c9f53-1999x1125.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;Built on top of a custom compiler, Tetsuwan’s ResearchOS makes it possible to execute automated experiments from natural-language instructions.&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;ResearchOS connects users to the automated lab, but the lab itself presents a formidable orchestration challenge. It is, after all, a menagerie of pipetting robots,&lt;sup class=&quot;body-3 agate&quot;&gt;1&lt;/sup&gt; robotic arms, and automated labware that all use different languages and all have their quirks. We implemented MHS to allow us to use Claude as an orchestration layer over that fleet by enabling these devices to communicate with one another and with the user. To test MHS, we put the platform to work on a citizen science project in Pacifica, California, running quantitative PCRs (qPCRs) to characterize sources of fecal contamination in the San Pedro Creek, which for decades have been &lt;a href=&quot;https://www.cbsnews.com/sanfrancisco/news/linda-mar-beach-pacifica-pollution-human-waste-contamination/&quot; target=&quot;_blank&quot; rel=&quot;noopener&quot;&gt;at dangerously high levels&lt;/a&gt;. &lt;/p&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Implementing MHS in a qPCR workflow&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;One of the most commonly used protocols in many biology labs, the polymerase chain reaction (PCR) copies DNA with nothing but a metal block, called a thermocycler, that heats up and cools down. DNA is a two-stranded molecule, and heating it separates the strands so they can be duplicated. Cooling the strands lets primers—short pieces of DNA that match the edges of the region you want copied—stick to those strands and mark where copying should start. Warming the strands back up, though not as much as before, lets an enzyme called a polymerase extend each primer along the strand it’s stuck to, copying it. qPCR adds a dye that glows brighter as copies accumulate, so we know how many copies there were to begin with. We can use this to measure how strongly a gene is switched on, to detect and quantify a pathogen in a patient sample, and, as in our case, to measure how much of a specific organism is present in an environmental sample.&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1999&quot; height=&quot;1011&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/38ee345e7d40b3346f1b484da91d62d854efc98b-1999x1011.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;A screenshot taken from the “procedure” page of ResearchOS, which shows users a graphical representation of their experiment after a protocol is uploaded.&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;qPCRs require a viscous, soap-like reagent known as a “master mix,” which contains the chemistry shared between reactions. These liquid properties make master mix especially prone to creating bubbles and foam when pipetted, which can cause inaccurate pipetting and degrade the quality of the experiment. With MHS, we were able to connect a camera that detects such errors and triggers an automated recovery process.&lt;/p&gt;&lt;figure&gt;&lt;video autoplay=&quot;&quot; controls=&quot;&quot; playsinline=&quot;&quot; muted=&quot;&quot; src=&quot;https://cdn.sanity.io/files/4zrzovbb/website/ab7f460b93d47a528fe89266b243a1093bca295e.mp4&quot;&gt;&lt;/video&gt;&lt;figcaption class=&quot;caption&quot;&gt;Claude, using MHS, operates a camera to take pictures of each transfer. The pictures are processed by a computer vision algorithm to identify pipetting errors, such as bubbles and foam. Claude can then intervene when an error is detected.&lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;In one case, the camera identified bubbles in the master mix, which was in a tube held by a robotic arm. There was nothing the robotic arm alone could do to get rid of the bubbles. So ResearchOS scanned the lab for MHS-connected devices that could help, and Claude suggested an error handling strategy to us via Slack: move the tube to a centrifuge and briefly spin it at a low speed to draw the liquid to the bottom of the well, eliminating the bubbles. Through MHS, Claude was then able to issue the appropriate commands to the centrifuge.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;This orchestration layer also allows protocols to stay hardware-independent. For example, a protocol might call for spinning a plate down at 15,000 × rpm for five minutes, without naming a specific type of centrifuge. ResearchOS can use MHS to query the network for a compatible centrifuge, learn its driver interface, and then use Claude to convert the force specified in the protocol into whatever parameters that specific machine accepts. For a machine that only takes rotor speed, for instance, that means dividing the force by the radius of the centrifuge’s rotor. The protocol author never even has to know which centrifuge was used, nor how the measurement was converted.&lt;/p&gt;&lt;figure&gt;&lt;video autoplay=&quot;&quot; controls=&quot;&quot; playsinline=&quot;&quot; muted=&quot;&quot; src=&quot;https://cdn.sanity.io/files/4zrzovbb/website/79c765cd8ec0c2d9e6d06b9a283c78c097dccad1.mov&quot;&gt;&lt;/video&gt;&lt;figcaption class=&quot;caption&quot;&gt;Multiple lab robots work in tandem to execute a qPCR workflow and troubleshoot errors.&lt;/figcaption&gt;&lt;/figure&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Improving compiler heuristics with MHS&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;We also used Claude to set up a closed-loop optimization experiment to improve our compiler, which translates high-level code into instructions our lab equipment can execute. We took our qPCR protocol and compiled it into a range of realistic worklists that spanned a variety of experimental setups, such as testing different primer sets with different combinations of samples, sample numbers, and replicates (multiple runs of the same sample). From this, we determined how many different types of liquid transfers our compiler could implement. We then tried out those transfers on a robot under varying conditions, and measured their accuracy and precision with a tracer dye. When an experiment finished, Claude retrieved the accuracy data from the plate reader via MHS, analyzed and visualized it, and suggested tweaks to improve our compiler’s model of transfer precision. With more precise predictions and known systematic offsets (predictable errors in measured values), the compiler was able to make more informed machine layout and tip-reuse tradeoffs, which will ultimately help make our experiments faster, cheaper, and more accurate.&amp;nbsp;&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Over the course of this experiment we tested 9,143 individual dispenses, 300 unique transfer types (liquid × tip × volume × dispense count × over-aspiration), and 1,508 measured conditions across four types of liquid. On held-out experiments, the model Claude and MHS helped refine predicted multi-dispense precision roughly 12% more accurately than the manufacturer’s technical specification, beating it on 31 of 45 runs (sign-test p ≈ 0.001). This increased to roughly 17% on our most-replicated data.&lt;/p&gt;&lt;h3 class=&quot;headline-6&quot;&gt;Preliminary data from the San Pedro Creek&lt;/h3&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Although these were just early tests, the preliminary data from our qPCR testing corroborated the San Pedro Creek Watershed Coalition’s &lt;a href=&quot;https://www.sfgate.com/local/article/pacifica-beach-human-waste-22279337.php&quot; target=&quot;_blank&quot; rel=&quot;noopener&quot;&gt;finding&lt;/a&gt; that humans are the primary contributor to fecal contamination in San Pedro Creek. We used qPCR to amplify fragments of bacterial DNA specific to different host organisms, such as humans, horses, birds, and dogs.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;We were able to detect the presence of &lt;em&gt;E. coli&lt;/em&gt; with a general 16S marker, as well as the presence of &lt;em&gt;Bacteroides&lt;/em&gt; bacteria using the AllBac primer. 16S is a ribosomal RNA gene shared by all bacteria. By designing primer sets to interrogate sequences of 16S that contain interspecies variations, the host species can be identified (in this case, &lt;em&gt;E. coli&lt;/em&gt;).&lt;/p&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1941&quot; height=&quot;1341&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/cf741b1d2a1c9cfe51d42dab0b064c01e22e155a-1941x1341.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;qPCR Amplification plot of HF183, a marker specific to bacterial species originating from human feces.&lt;/figcaption&gt;&lt;/figure&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;1999&quot; height=&quot;1039&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/4aa15a4df3806c23a15bd6265ad71f2536cce278-1999x1039.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;The qPCR experiment’s amplification curves show that the only source-specific marker detected was for humans (BacH, HF183). Note that Mean Cts are not comparable between markers. &lt;/figcaption&gt;&lt;/figure&gt;&lt;p class=&quot;body-2 serif&quot;&gt;We also saw clear amplification of human-associated &lt;em&gt;Bacteroides&lt;/em&gt; using the HF183 and BacH primers. No other host-specific &lt;em&gt;Bacteroides &lt;/em&gt;were detectable in our experiment. In future experiments, we aim to better characterize the source of contamination and quantitatively evaluate the concentration of human-associated &lt;em&gt;Bacteroides&lt;/em&gt; in the wastewater.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;Ultimately, the improved device integration, orchestration, and real-time error recovery made possible by MHS will be critical to bridging the gap between hardware, scientists, and models. As tools like ResearchOS and MHS improve the capabilities of lab automation, we believe experimentation will become increasingly accessible, reproducible, and programmable.&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;em&gt;To read more about the optimization and community science aspects of this project, &lt;a href=&quot;http://tetsuwan.com/blog/mhs&quot; target=&quot;_blank&quot; rel=&quot;noopener&quot;&gt;visit our blog&lt;/a&gt;.&lt;/em&gt;&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;/p&gt;&lt;p class=&quot;body-2 serif&quot;&gt;&lt;sup class=&quot;body-3 agate&quot;&gt;1&lt;/sup&gt; &lt;em&gt;Known as “liquid handlers” within lab automation. Note that 6-DoF arms are not the same as liquid handlers; liquid handlers are optimized specifically for pipetting rather than for general use. Workcells—which combine multiple lab robots into a single system—usually employ both liquid handlers (for pipetting) and robotic arms (for transferring plates and other labware).&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/footer&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Hardware vendors and the software companies that support them are also building MHS support into their equipment so AI agents can more easily discover and operate their devices. For example:&lt;/p&gt;&lt;ul class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;li&gt;Amazon Web Services will support MHS through Strands Robots, the library for connecting AI agents to physical devices. AWS will provide participants a private, pre-release version of the Strands Robots package for the duration of the MHS research preview.&lt;/li&gt;&lt;li&gt;Automata is adding MHS support to LINQ, their lab automation platform, to perform intelligent error handling of instruments in autonomous labs.&lt;/li&gt;&lt;li&gt;Danaher and Anthropic are actively exploring how MHS-supported capabilities could enable its smart instruments and autonomous laboratories to scale biomedical research and development.&lt;/li&gt;&lt;li&gt;Doosan Robotics is testing MHS with their robotic arms, including to perform automated quality assurance and coordinate tasks across multiple robots.&lt;/li&gt;&lt;li&gt;MBF Bioscience is building an MHS driver for ScanImage, the software that runs laser-scanning microscopes in hundreds of neuroscience labs worldwide, to integrate AI agents into real-time data analysis and experiments.&lt;/li&gt;&lt;li&gt;QIAGEN is experimenting with MHS through a working proof of concept on its nucleic acid purification platform, QIAsymphony Connect, showing how AI agents could help laboratories troubleshoot instrument issues faster, guide operators through recovery, and improve instrument uptime while reducing risk to biological samples.&lt;/li&gt;&lt;li&gt;Tecan is adding MHS support for their Fluent liquid handling platforms so AI agents can discover and operate them directly.&lt;/li&gt;&lt;li&gt;Universal Robots has had early access to MHS and plans to add support to its robotics platform. &lt;/li&gt;&lt;/ul&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;joining-the-research-preview&quot;&gt;Joining the research preview&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;These early results from our partners are encouraging, but we have more work to do on the standard before we open-source it. As a large language model, Claude learns about the physical world through text and images, meaning its spatial and physical reasoning have limitations that still require expert oversight. When working with protein samples, for example, Genentech researchers had to guide Claude to recognize that errors caused by foaming in samples were physical failures, not software bugs, that could only be mitigated through the appropriate physical corrections. &lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;MHS also doesn’t yet work with hardware that lacks a programming interface, so we’re working with the manufacturers of such devices to build in MHS drivers. Many developers already use Claude Code to work with individual pieces of physical equipment; for the next phase of MHS, we hope to expand the standard to cover more of the devices developers build on. Early adopters include Hugging Face, who are adding MHS support in LeRobot, their robotics library, and Raspberry Pi, who are enabling MHS integration across a number of their products following successful tests using their Camera MHS Driver. &lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We will also use the research preview to build additional safety evaluations with our launch partners and strengthen protections for the use of AI in the physical world. We are developing a physical safety roadmap to further bolster our safeguards policy and enforcement coverage against the risk of misuse. When we open-source MHS, we will release findings from the research preview as part of our guidance for deploying the standard safely.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We’re inviting stakeholders across industries to join the waitlist for our research preview of MHS. If you’d like to participate, &lt;a href=&quot;https://www.modelhardwarestandard.com/&quot; target=&quot;_blank&quot; rel=&quot;noopener noreferrer&quot;&gt;submit your interest here&lt;/a&gt;.&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;acknowledgments&quot;&gt;Acknowledgments&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;MHS began as a collaboration between Alek Kemeny on Anthropic’s &lt;a href=&quot;http://anthropic.com/beneficial-deployments&quot; target=&quot;_blank&quot; rel=&quot;noopener noreferrer&quot;&gt;Beneficial Deployments team&lt;/a&gt; and Arco Bast, a postdoctoral scientist at HHMI Janelia Research Campus. Bast was running complex brain-imaging experiments on a rig that combined lasers, motorized focusers, and specialized cameras from different vendors with no common interface. To speed up his experiments, he developed a shared memory dictionary that enabled the instruments to communicate with one another at memory speed. Kemeny and Bast worked together to integrate AI models into that interface.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We thank everyone who has contributed to this work so far, including, but not limited to, Aaron Boswell, Ben Arthur, Boaz Mohar, Gagan Bhat, Mark Kittisopikul, Nadine Yasser, Nick Purcell, Takashi Kawase, and Virginie Ruetten. We look forward to moving MHS forward with our industry partners and, soon, with the open-source community.&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__postFooter&quot;&gt;&lt;/div&gt;&lt;/article&gt;</description><link>https://www.anthropic.com/news/model-hardware-standard-research-preview</link><guid isPermaLink="false">https://www.anthropic.com/news/model-hardware-standard-research-preview</guid><pubDate>Wed, 26 Aug 2026 16:00:00 GMT</pubDate></item><item><title>Expanding our support for scientists</title><description>&lt;article&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__hero&quot;&gt;&lt;div class=&quot;PostDetail-module-scss-module__UQuRMa__illustrationHeroWrapper&quot;&gt;&lt;div class=&quot;Illustration-module-scss-module__WyGOtq__root Illustration-module-scss-module__WyGOtq__aspect-wide Illustration-module-scss-module__WyGOtq__padding-lg Illustration-module-scss-module__WyGOtq__radius-lg bg-olive&quot;&gt;&lt;div class=&quot;Illustration-module-scss-module__WyGOtq__inner&quot;&gt;&lt;img alt=&quot; Expanding our support for scientists&quot; loading=&quot;lazy&quot; width=&quot;1000&quot; height=&quot;1000&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/46e4aa7ea208ed440d5bd9e9e3a0ee66bc336ff1-1000x1000.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper&quot;&gt;&lt;article&gt;&lt;div class=&quot;&quot;&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__body&quot; data-theme=&quot;ivory&quot;&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;As Claude becomes increasingly capable at scientific research, we are focusing on building products and programs to support the research community. In June, we launched &lt;a href=&quot;https://www.anthropic.com/news/claude-science-ai-workbench&quot;&gt;Claude Science&lt;/a&gt;, a product that integrates the tools that researchers most commonly use, produces auditable artifacts, and provides flexible access to computing resources. We have also continued to broaden our &lt;a href=&quot;https://www.anthropic.com/news/ai-for-science-program&quot;&gt;AI for Science program&lt;/a&gt;, which provides free credits to researchers working on high-impact scientific projects. &lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Starting today, we are announcing a significant expansion of these efforts. We are opening 10,000 seats for scientists around the world to access Claude subscriptions for free and at discounted rates for one year through our new &lt;a href=&quot;http://claude.com/programs/team-plan-for-scientists&quot;&gt;Claude team plan for scientists&lt;/a&gt;. Standard seats will be free and premium seats with 5x usage limits will be available for $15 per month. Over the coming months, we intend to extend this program well beyond the initial 10,000 seats.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Alongside these subscriptions, we are also expanding the scope and scale of our &lt;a href=&quot;https://www.anthropic.com/news/ai-for-science-program&quot;&gt;AI for Science&lt;/a&gt; program. To date, we’ve largely supported scientists using Claude for biological sciences. We are now looking to offer credits for researchers in other scientific fields as well, including those working on ambitious, compute heavy-research, such of the kind that resulted in progress on the &lt;a href=&quot;https://www.anthropic.com/research/riemann-zeta&quot;&gt;Riemann zeta function&lt;/a&gt; and &lt;a href=&quot;https://www.anthropic.com/research/Claude-accelerates-protein-design&quot;&gt;Claude’s work on protein design&lt;/a&gt;. &lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;By helping scientists access and increase their usage of Claude through subscriptions, credits, and products like &lt;a href=&quot;https://claude.com/product/claude-science&quot;&gt;Claude Science&lt;/a&gt;, we aim to radically accelerate scientific discovery.&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;ways-to-access-claude&quot;&gt;&lt;strong&gt;Ways to access Claude&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;To register for our Claude team plan for scientists, please &lt;a href=&quot;http://claude.ai/redirect/website.v1.5ec6e3bf-575c-49a4-ba04-7215cfdf4c80/labs-verification/attestation&quot;&gt;complete the verification form here&lt;/a&gt;. You must be a principal investigator or equivalent at an academic or nonprofit research institution to qualify; once verified, you can add the researchers in your lab to your plan. &lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;As your lab makes use of your allotted credits and requires more usage than standard or premium plans provide, you can &lt;a href=&quot;https://docs.google.com/forms/d/e/1FAIpQLSfwDGfVg2lHJ0cc0oF_ilEnjvr_r4_paYi7VLlr5cLNXASdvA/viewform?usp=dialog&quot;&gt;apply to our AI for Science program&lt;/a&gt; for up to $50,000 in credits per project. Any researcher is eligible to apply.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;For now, researchers working in biology and chemistry will still be limited to our Opus-class models. Claude Fable models will &lt;a href=&quot;https://www.anthropic.com/news/improving-fable-5-s-biology-safeguards&quot;&gt;continue to block&lt;/a&gt; professional biology and drug development queries because of their potential dual-use risks. We’re working in partnership with the US government to establish an access program for life sciences professionals to use Mythos-class models for life sciences research and development. We have now enrolled our first participants, and expect to share more and increase access soon.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;br&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__postFooter&quot;&gt;&lt;/div&gt;&lt;/article&gt;</description><link>https://www.anthropic.com/news/expanding-support-for-scientists</link><guid isPermaLink="false">https://www.anthropic.com/news/expanding-support-for-scientists</guid><pubDate>Wed, 26 Aug 2026 16:00:00 GMT</pubDate></item><item><title>Funding better evaluations of AI’s impact on wellbeing</title><description>&lt;article&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__hero&quot;&gt;&lt;div class=&quot;PostDetail-module-scss-module__UQuRMa__illustrationHeroWrapper&quot;&gt;&lt;div class=&quot;Illustration-module-scss-module__WyGOtq__root Illustration-module-scss-module__WyGOtq__aspect-wide Illustration-module-scss-module__WyGOtq__padding-lg Illustration-module-scss-module__WyGOtq__radius-lg bg-heather&quot;&gt;&lt;div class=&quot;Illustration-module-scss-module__WyGOtq__inner&quot;&gt;&lt;img alt=&quot;Funding better evaluations of AI’s impact on wellbeing&quot; loading=&quot;lazy&quot; width=&quot;1000&quot; height=&quot;1000&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/f6a742f45bdb584cdffd3f00d54751b12bbee2ba-1000x1000.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper&quot;&gt;&lt;article&gt;&lt;div class=&quot;&quot;&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__body&quot; data-theme=&quot;ivory&quot;&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We’re launching a $5 million grant program to fund independent research into how AI impacts users’ wellbeing. The program will provide direct funding, access to our models, and technical support to grantees building open-source evaluations that help the AI industry measure how our models affect those who use them. Grantees will work fully independently, and will publish their work as open-source projects that any developer can make use of.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;AI systems have become central to how many people work, learn, and solve problems. They’ve also become conversational partners and can be &lt;a href=&quot;https://www.anthropic.com/news/how-people-use-claude-for-support-advice-and-companionship&quot;&gt;sources of emotional support&lt;/a&gt; during difficult times. But as an industry, we are still working towards developing clear standards for how models should behave in these conversations, for example, when a user begins to seek companionship from a model, or uses AI to navigate a mental health crisis.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Furthermore, wellbeing is a particularly difficult area to evaluate. For most model behaviors, we can look at a single answer and determine whether it is accurate and appropriate. But assessing wellbeing requires much more context. For example, a user in distress might not share thoughts of self-harm right away; the need for a more cautious response might only become clear over the course of a long conversation. And a response that might be reasonable in one context might be harmful in another. For example, Claude might give advice on balanced diets and workout routines to a user who asks about losing weight, but if the user has demonstrated a history of disordered eating, that response could be inappropriate, and potentially actively harmful.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We work to &lt;a href=&quot;https://www.anthropic.com/news/protecting-well-being-of-users&quot;&gt;develop safeguards&lt;/a&gt; to identify such conversations and help ensure Claude responds appropriately, and we &lt;a href=&quot;https://www.anthropic.com/research/claude-personal-guidance&quot;&gt;publish research&lt;/a&gt; into the types of conversations people have with Claude to better inform how we develop our safeguards, how we evaluate them, and other measures we can take to protect users’ wellbeing. But these are nuanced considerations, and the stakes are significant. The right approach will need to evolve alongside our models and their uses.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;By funding the creation of independent evaluations and benchmarks of user wellbeing, we hope to invite more people to lend their expertise to this emerging and critical field, including clinicians, psychologists, methodologists, and others.&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-4 post-heading&quot; id=&quot;towards-more-effective-wellbeing-evaluations-and-benchmarks&quot;&gt;Towards more effective wellbeing evaluations and benchmarks&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;As part of this program, we’re &lt;a href=&quot;https://www-cdn.anthropic.com/files/4zrzovbb/website/5ecb637cb206057cb93cf4a9e72e843fda5e9892.pdf&quot; target=&quot;_blank&quot; rel=&quot;noopener noreferrer&quot;&gt;sharing guidance&lt;/a&gt; from our Safeguards team on what we believe makes a wellbeing evaluation rigorous enough to build on, along with the common challenges that can limit an evaluation’s usefulness.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In brief, we’re seeking evaluations that:&lt;/p&gt;&lt;ul class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;li&gt;State clearly what they are measuring (i.e., what counts as a pass or fail, and why it matters);&lt;/li&gt;&lt;li&gt;Involve clinical and subject-matter experts in the design and validation;&lt;/li&gt;&lt;li&gt;Test both precautions and harms (i.e., evaluate the risk of both overcompliance and overrefusal);&lt;/li&gt;&lt;li&gt;Reflect how users actually use AI (often, this means constructing scenarios that represent multi-turn conversations, where risk escalates and context shifts over the course of a long conversation);&lt;/li&gt;&lt;li&gt;Validate their graders against real subject-matter experts.&lt;/li&gt;&lt;/ul&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;To learn more about the grant program and apply, &lt;a href=&quot;https://docs.google.com/forms/d/e/1FAIpQLSfmUDtpfg-ztmQPkCbwx-VAe_urX48sthbqs8GmZUT9irRSDQ/viewform?usp=dialog&quot; target=&quot;_blank&quot; rel=&quot;noopener noreferrer&quot;&gt;see our application form&lt;/a&gt;. For more on building strong wellbeing evaluations and benchmarks, &lt;a href=&quot;https://www-cdn.anthropic.com/files/4zrzovbb/website/5ecb637cb206057cb93cf4a9e72e843fda5e9892.pdf&quot; target=&quot;_blank&quot; rel=&quot;noopener noreferrer&quot;&gt;read our guidance&lt;/a&gt;. Applications are due by September 21; applicants who are selected to submit full proposals will be notified by October 5.&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__postFooter&quot;&gt;&lt;/div&gt;&lt;/article&gt;</description><link>https://www.anthropic.com/news/wellbeing-research-grants</link><guid isPermaLink="false">https://www.anthropic.com/news/wellbeing-research-grants</guid><pubDate>Mon, 24 Aug 2026 16:00:00 GMT</pubDate></item><item><title>How Claude’s text watermark works</title><description>&lt;article&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__hero&quot;&gt;&lt;div class=&quot;PostDetail-module-scss-module__UQuRMa__illustrationHeroWrapper&quot;&gt;&lt;div class=&quot;Illustration-module-scss-module__WyGOtq__root Illustration-module-scss-module__WyGOtq__aspect-wide Illustration-module-scss-module__WyGOtq__padding-lg Illustration-module-scss-module__WyGOtq__radius-lg bg-heather&quot;&gt;&lt;div class=&quot;Illustration-module-scss-module__WyGOtq__inner&quot;&gt;&lt;img alt=&quot;How Claude’s text watermark works&quot; loading=&quot;lazy&quot; width=&quot;1000&quot; height=&quot;1000&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/33dbe8f783d4835a838b4c4ae85d3c04e352fee1-1000x1000.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper&quot;&gt;&lt;article&gt;&lt;div class=&quot;ArticleDetail-module-scss-module__YVTUHa__grid&quot;&gt;&lt;div class=&quot;ArticleDetail-module-scss-module__YVTUHa__sidebar-container&quot;&gt;&lt;aside class=&quot;page-wrapper Sidebar-module-scss-module__5Xbtsq__sidebar contentFadeUp&quot; data-theme=&quot;ivory&quot;&gt;&lt;button type=&quot;button&quot; class=&quot;Sidebar-module-scss-module__5Xbtsq__sidebar-toggle&quot; aria-label=&quot;Show table of contents&quot; aria-expanded=&quot;false&quot;&gt;&lt;span aria-hidden=&quot;true&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;24&quot; height=&quot;24&quot; viewBox=&quot;0 0 24 24&quot;&gt;&lt;path d=&quot;M3.25 17.75v-1.5h17.5v1.5H3.25Zm0-5.2v-1.5h17.5v1.5H3.25Zm0-5.175v-1.5h17.5v1.5H3.25Z&quot; fill=&quot;#141413&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/span&gt;&lt;/button&gt;&lt;button class=&quot;Sidebar-module-scss-module__5Xbtsq__sidebar-button&quot; aria-expanded=&quot;false&quot;&gt;&lt;span class=&quot;caption bold&quot;&gt;&lt;/span&gt;&lt;span aria-hidden=&quot;true&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;8&quot; height=&quot;5&quot; viewBox=&quot;0 0 8 5&quot;&gt;&lt;path d=&quot;M7.3016 0.231808C7.44932 0.0678162 7.70306 0.0546398 7.86724 0.20212C8.03137 0.349888 8.04461 0.603568 7.89692 0.767766L4.29684 4.76791L4.23434 4.82417C4.16662 4.87328 4.08425 4.89995 3.99918 4.89995C3.88588 4.89989 3.77733 4.85213 3.70152 4.76791L0.10144 0.767766L0.0537825 0.702139C-0.040206 0.541753 -0.0124254 0.331356 0.131128 0.20212C0.274775 0.0728844 0.486972 0.0674593 0.636608 0.1779L0.696765 0.231808L3.99918 3.90148L7.3016 0.231808Z&quot; fill=&quot;#141413&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/span&gt;&lt;/button&gt;&lt;div&gt;&lt;nav aria-label=&quot;Article sections&quot;&gt;&lt;ul class=&quot;Sidebar-module-scss-module__5Xbtsq__header-list&quot;&gt;&lt;/ul&gt;&lt;/nav&gt;&lt;/div&gt;&lt;/aside&gt;&lt;/div&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__body ArticleDetail-module-scss-module__YVTUHa__body-container&quot; data-theme=&quot;ivory&quot;&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Future Claude models will generate text that contains a watermark. This is a way of determining the likelihood that Claude was involved in writing the text, and we, along with several other major AI providers, are implementing this change to comply with the EU AI Act.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In this article, we share answers to some of the questions we’ve received about how our chosen watermarking method works, whether it affects Claude’s outputs, and why we’re making this change. To summarize:&lt;/p&gt;&lt;ul class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;li&gt;We use a method of watermarking that does not have any practical impact on the quality or content of Claude’s outputs;&lt;/li&gt;&lt;li&gt;The difference between watermarked and un-watermarked text will not be distinguishable to readers;&lt;/li&gt;&lt;li&gt;Nothing is added to the text and there are no hidden characters;&lt;/li&gt;&lt;li&gt;Watermarking doesn’t require extra tokens, and will not be more expensive;&lt;/li&gt;&lt;li&gt;Watermarking carries no identifying information and can’t be traced to a specific person, organization, or chat;&lt;/li&gt;&lt;li&gt;Watermarking won’t be specific to Claude. As of August 2, the EU requires AI providers serving its market to mark AI-generated content. Other major model developers have signed the same Code of Practice and will be implementing their own watermarks.&lt;/li&gt;&lt;/ul&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;what-is-watermarking&quot;&gt;&lt;strong&gt;What is watermarking?&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Large language models like Claude work by generating one word at a time. Each time the model decides on the next word, it chooses among a list of potential candidates, ultimately selecting the most sensible or likely based on the preceding text. Take the sentence “The weather today was cold and…”. The next word is very unlikely to be “sugary.” But it is quite likely to be “overcast” or “grey.” Under most circumstances, it doesn’t matter much to the reader which of these latter two words the model ultimately chooses—the meaning of the sentence is largely the same either way. In cases like this, the choice is settled by a random number.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Watermarking uses low-stakes choices like these—which occur many times over a piece of generated text—to leave a pattern in Claude’s responses. That pattern is undetectable to the reader, but &lt;em&gt;is&lt;/em&gt; detectable to anyone who has a key that encodes it. When watermarking is used, choices are still made at random, but the &lt;em&gt;source&lt;/em&gt; of the randomness is different. Instead of using an arbitrary random number generator to pick the next word, watermarking uses the key and a few words that come before to settle what word the model should pick. That is, the words that Claude picks are still random, but now, one can check the sequence of words and see if it’s consistent with the choices Claude would make if it was using the key. If it is, one can assign a probability that the text was generated by Claude.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Importantly, it isn’t that the model will now always be biased toward overcast or grey. Just as with non-watermarked text, overcast might be selected in one sentence, grey in the next, depending on the words that came before. And it’s not the case that the watermarking method pushes Claude to choose a word it wouldn’t have considered anyway (for instance, it wouldn’t make Claude pick a word like “nubilous”—an obscure&lt;sup class=&quot;caption Body-module-scss-module__z40yvW__sup&quot;&gt;1&lt;/sup&gt; synonym for overcast or grey that Claude almost certainly wouldn’t use under normal circumstances).&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;how-does-watermarking-affect-claudes-outputs&quot;&gt;&lt;strong&gt;How does watermarking affect Claude’s outputs?&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Watermarking does not impact the quality of Claude’s output. To a reader, a watermarked response is indistinguishable from an unwatermarked one (in this way, AI watermarks differ substantially from their namesakes on banknotes, other physical objects, and some digital documents, which &lt;em&gt;are&lt;/em&gt; visible to the naked eye).&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In internal testing, we’ve seen no impact of watermarking on the content, level of creativity, or readability of Claude’s text. In the &lt;a href=&quot;https://www.nature.com/articles/s41586-024-08025-4&quot;&gt;SynthID-Text paper&lt;/a&gt;, which introduced the technique we use, Google DeepMind tested this impact by serving a model that used watermarking to a portion of their Gemini traffic and comparing thumbs-up and thumbs-down ratings. They found no statistically significant differences from the unwatermarked model. And in a controlled study, human raters comparing watermarked and unwatermarked answers side-by-side saw no difference in quality.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;A useful analogy is to imagine you’re playing a game like Monopoly. On each turn, each player moves a random number of spaces around the board according to the roll of a die. Suppose that, instead of rolling the die to get this randomness, we decided to use a book of the digits of pi.&lt;sup class=&quot;caption Body-module-scss-module__z40yvW__sup&quot;&gt;2&lt;/sup&gt; We start from a randomly-chosen digit (say, the 1,012,845th after the decimal place, which happens to be a 6), and from that point on each player simply uses the next digit in the sequence as their next “roll.&quot;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;For all intents and purposes, the moves are still random: it makes no difference to the players—or to the outcome of the game—whether the randomness comes from pi or from dice rolls each time. But if we could see the sequence of all the moves after the game (and we knew the value of pi), we could work out whether this was a game that likely used pi to determine its moves. The game that used pi is, in a sense, “watermarked.&quot;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;It’s the same for Claude-generated text. Watermarking doesn’t change the meaning or experience for the person reading it, but if you wanted to check after the fact whether the text was likely generated by Claude, the watermark allows you to do so.&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;which-specific-method-of-watermarking-do-you-use&quot;&gt;&lt;strong&gt;Which specific method of watermarking do you use?&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Claude’s text watermark is a version of the SynthID-Text approach published by Google DeepMind in a &lt;a href=&quot;https://www.nature.com/articles/s41586-024-08025-4&quot;&gt;&lt;em&gt;Nature&lt;/em&gt; paper&lt;/a&gt; in 2024. It belongs to a family of approaches that go back to a proposal by Scott Aaronson in 2022, all of which share the same design principle that we described above—the watermark only changes the source of the randomness used to pick among words. &lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;There are limitations to the effectiveness of watermarking. Using our key, one can only answer the question “What is the likelihood this was partly written by Claude?” It doesn’t confirm whether the text was human-written, and it can’t tell whether the text was written by a different AI (even if that other AI uses watermarking, it would have a different key; it might also use a different watermarking method altogether). Detecting a watermark also doesn’t work well on small samples, where there are fewer word choices and thus less information to go on. As a passage increases in length, confidence about Claude’s involvement increases too.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Watermarking is sparser on factual passages where there are fewer choices that can be made without decreasing the accuracy of the text. For example, take the sentence “Isaac Newton’s most famous work was called &lt;em&gt;Principia&lt;/em&gt;…”. It really matters whether the next word is “&lt;em&gt;Mathematica&lt;/em&gt;” (it’s the only right answer), so the watermark would have nothing to act on. The same is true for proofreading. If you hand Claude a piece of writing and ask it to edit only the grammar and punctuation and nothing else, the watermark can only live in the handful of corrections, which might be too few to register.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;what-about-cases-where-claude-has-proofread-or-edited-human-text&quot;&gt;&lt;strong&gt;What about cases where Claude has proofread or edited human text?&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;The watermark only applies to words Claude chooses. When Claude proofreads text written by a person, what it gives back has generally only been lightly edited; because nearly all the words are the person’s, there’s very little (if anything) for the watermark to attach to. Depending on the length of the text and how heavily Claude has edited it, those changes might not be enough to make Claude’s involvement detectable. The more Claude writes, the more decisions it has to make, and the more space there is for a watermark.&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;what-about-code-&quot;&gt;&lt;strong&gt;What about code?&amp;nbsp;&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;As we noted above, AI watermarking takes advantage of decisions where either choice of a word would be equally good. Where an &lt;em&gt;exact&lt;/em&gt; output is required—where there isn’t a choice, and something would be factually wrong or a piece of code would break if a different term was chosen—the watermark isn’t applied.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;For example, once the model has written “2 + 2 =”, there is a very clear best choice for the next token (if the model is completing the sum, there isn’t an answer that’s equally as good as “4”; if it’s talking about George Orwell’s &lt;em&gt;Nineteen Eighty-Four&lt;/em&gt;, there isn’t an answer that’s equally as good as “5”). The “nudge” of the watermark wouldn’t be applied here. For the same reason, code—which in very many cases has to be exact—has generally less watermarking than some other forms of text.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Having said that, in areas where there &lt;em&gt;is&lt;/em&gt; an arbitrary choice between particular words or terms within the code, the watermark can be used, such as comments within code. But by definition, it will have a negligible effect on the actual code produced.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;what-does-this-mean-for-users-&quot;&gt;&lt;strong&gt;What does this mean for users? &lt;br&gt;&lt;/strong&gt;&lt;/h2&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;does-this-slow-the-model-down-or-make-it-more-expensive&quot;&gt;&lt;strong&gt;Does this slow the model down, or make it more expensive?&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;br&gt;No. Watermarking has a negligible impact on the speed of models, and because it produces no extra tokens, the model is the same price to serve and use.&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;can-a-watermark-be-traced-back-to-me-or-my-organization&quot;&gt;&lt;strong&gt;Can a watermark be traced back to me or my organization?&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;No. The watermarking applies to Claude and its outputs. It doesn’t identify anything to do with individual users. There’s nothing in the watermark, or its key, that would allow anyone to recover any information about the user, their organization, or their chats with Claude.&lt;br&gt;&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;229181bf1d83&quot;&gt;&lt;strong&gt;&lt;em&gt;Why&lt;/em&gt; are you watermarking Claude’s outputs?&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We’re implementing watermarking to comply with the EU AI Act. Anthropic, along with several other major AI model providers and around &lt;a href=&quot;https://digital-strategy.ec.europa.eu/en/news/strong-backing-code-practice-transparency-ai-generated-content&quot;&gt;190 total signatories&lt;/a&gt;, signed the EU Code of Practice on Transparency of AI-Generated Content in July 2026. This requires AI system providers to use methods of “marking” AI-generated text. We’re applying watermarking globally at launch because we don&#39;t yet have a durable way to scope it by region. However, we will continue to evaluate different approaches, and will share updates when we have them.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;other-questions&quot;&gt;&lt;strong&gt;Other questions&lt;/strong&gt;&lt;/h2&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;how-do-i-check-if-a-piece-of-text-was-written-by-claude&quot;&gt;&lt;strong&gt;How do I check if a piece of text was written by Claude?&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We will soon be offering a watermark detection API. We’re in the process of working out the details of its implementation.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;what-about-images-and-other-files&quot;&gt;&lt;strong&gt;What about images and other files?&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;When Claude produces a file of a supported type (such as a .png, .jpg, or .svg), it will attach a content credential in the form of a small, cryptographically signed note in the file’s metadata, saying that the file was made or processed with Claude. This is an open industry standard called &lt;a href=&quot;https://c2pa.org/&quot;&gt;C2PA&lt;/a&gt;—the same used by camera manufacturers and in photo-editing software to record where an image came from. Any C2PA-aware tool can read it; we’ll be providing our own where you can drop a file and check.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;This metadata label is very different from a watermark. Nothing in the file changes—it is not embedded or hidden. As with text, the credential only says Claude was involved in producing the file; it doesn’t include any identifying information.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;cant-someone-just-edit-the-text-to-get-around-the-watermarking&quot;&gt;&lt;strong&gt;Can’t someone just edit the text to get around the watermarking?&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;To some extent, yes. Light editing probably won’t remove the watermark completely; a complete rewrite where every word is replaced will. In the latter case, of course, it’s arguable whether the text can any longer be described as AI-generated.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;what-does-a-watermark-actually-prove&quot;&gt;&lt;strong&gt;What does a watermark actually prove?&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;A watermark can only determine that Claude was likely involved with the content at some point. It cannot distinguish “Claude wrote this” from “Claude heavily edited this.”&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;do-watermarks-apply-to-translations&quot;&gt;&lt;strong&gt;Do watermarks apply to translations?&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Yes. A translation produced by Claude carries a watermark, because in this case every word is chosen by Claude.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;what-about-older-claude-models&quot;&gt;&lt;strong&gt;What about older Claude models?&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;The EU law includes a transition period for Anthropic models launched before August 2, 2026, and we’re working to add watermarking for those models as well. This will be rolled out over the coming months.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;how-does-this-differ-from-ai-detection-software-like-pangram&quot;&gt;&lt;strong&gt;How does this differ from AI detection software, like Pangram?&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;AI detection software uses a different method, because the companies that provide it don’t have our key. Among other things, those services look at aspects of the text like the subtle (and not-so-subtle) “tells” that often appear in AI’s phrasing. For example, AI models appear to be fond of the construction “this isn’t [X], it’s [Y]”, and use the word “quietly” a lot more than you might expect. Picking up on these patterns is fundamentally different from checking for a watermark.&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;does-this-change-who-owns-a-given-output-or-who-is-legally-responsible-for-it&quot;&gt;&lt;strong&gt;Does this change who owns a given output, or who is legally responsible for it?&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;No. A watermark only helps test whether Claude might have produced or processed the content. It doesn’t say anything about ownership or authorship, and doesn’t change a user’s rights under our terms. We only apply the watermark when Claude was involved in processing the content or file.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;br&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__postFooter&quot;&gt;&lt;div class=&quot;PostDetail-module-scss-module__UQuRMa__footnotes&quot;&gt;&lt;h4 class=&quot;headline-5&quot;&gt;Footnotes&lt;/h4&gt;&lt;ol&gt;&lt;li id=&quot;footnote-1&quot;&gt;Or, you might say, nubilous—which is also a synonym for “obscure.”&lt;/li&gt;&lt;li id=&quot;footnote-2&quot;&gt;Pi is technically predictable, but any run of digits from somewhere in the middle of pi is indistinguishable from a run of rolls of a ten-sided die. Also, set aside the fact that the dice in Monopoly go from 1 to 6 whereas a digit of pi can be from 0 to 9; the analogy isn’t perfect.&lt;/li&gt;&lt;/ol&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;</description><link>https://www.anthropic.com/news/claude-text-watermark</link><guid isPermaLink="false">https://www.anthropic.com/news/claude-text-watermark</guid><pubDate>Thu, 13 Aug 2026 16:00:00 GMT</pubDate></item><item><title>Improving Fable 5&#39;s biology safeguards</title><description>&lt;article&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__hero&quot;&gt;&lt;div class=&quot;PostDetail-module-scss-module__UQuRMa__illustrationHeroWrapper&quot;&gt;&lt;div class=&quot;Illustration-module-scss-module__WyGOtq__root Illustration-module-scss-module__WyGOtq__aspect-wide Illustration-module-scss-module__WyGOtq__padding-lg Illustration-module-scss-module__WyGOtq__radius-lg bg-heather&quot;&gt;&lt;div class=&quot;Illustration-module-scss-module__WyGOtq__inner&quot;&gt;&lt;img alt=&quot;Improving Fable 5&#39;s biology safeguards&quot; loading=&quot;lazy&quot; width=&quot;1000&quot; height=&quot;1000&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/e253e6c4926deb09baf67f41e4e24e8028ea5f36-1000x1000.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper&quot;&gt;&lt;article&gt;&lt;div class=&quot;&quot;&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__body&quot; data-theme=&quot;ivory&quot;&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We’re making updates to Claude Fable 5’s biology safeguards in a way that substantially reduces false positives. Fable 5 users will now experience many fewer “fallbacks”—where the system switches to a less capable model after they make a biology-related query. In our testing, this update reduced &lt;em&gt;biology-related&lt;/em&gt; fallbacks by about 85% across our product surfaces.&lt;sup class=&quot;caption Body-module-scss-module__z40yvW__sup&quot;&gt;1&lt;/sup&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Fable 5 will thus be able to assist with a wider range of biology tasks.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In practice, users should see far fewer fallbacks on everyday health and educational questions—for example, interpreting lab results, understanding symptoms, and learning about biology in an educational context. Healthcare professionals will be able to receive more support from Fable 5 on clinical tasks.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We believe the greatest opportunity for AI to positively affect the world is in biology and medicine, and we&#39;re investing significantly in building a responsible way to give biologists frontier access. Today, Fable still falls back to Opus 5 for requests we consider dual-use—including virology, toxicology, and molecular design—so it isn&#39;t yet usable for professional biology research and drug development. We&#39;re committed to closing that gap through trusted access pathways for frontier biology capabilities.&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;why-we-built-strong-biology-safeguards&quot;&gt;Why we built strong biology safeguards&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Our objective is to get Fable 5’s frontier capabilities into the hands of as many of our users as possible, as quickly as possible. However, to do so, we need to manage the increasing risks that come with models this capable. One such risk is in the field of biology: Fable 5 can now outperform experts on some highly complex biological tasks and provide operational support on others. That means that it can provide genuine assistance to a researcher developing a new medical treatment (which is the reason we’re so keen to widen access to the model via both classifier improvements and trusted access programs). But in the wrong hands, those same capabilities could be used by a malicious actor, for example in developing a biological weapon. Our &lt;a href=&quot;https://www-cdn.anthropic.com/d00db56fa754a1b115b6dd7cb2e3c342ee809620.pdf&quot;&gt;capability assessments&lt;/a&gt; show that Fable 5 could provide significant &lt;em&gt;uplift&lt;/em&gt; to such an actor—that is, it could provide them with capabilities they could not find anywhere else.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;It’s often difficult to tell apart beneficial and harmful uses of AI in biology. For example, in some cases researching a treatment for a disease requires scientists to produce the dangerous compounds that &lt;em&gt;cause&lt;/em&gt; that disease in the first place. This is most obvious for live vaccines, which require scientists to grow the same pathogen they’re aiming to prevent. It’s also the case for some medicines. To develop the drug captopril, which treats hypertension, scientists isolated toxic components of snake venom that crash blood pressure in humans. As new biological capabilities develop on the frontier of AI, we need to be cautious to ensure that the new risks they pose do not materialize ahead of their potential scientific benefits.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Sophisticated actors who wish to use our models to do harm know how to exploit this ambiguity to obscure their intent, making dangerous tasks look like ordinary research pursuits. The US Intelligence Community’s &lt;a href=&quot;https://www.dni.gov/files/ODNI/documents/assessments/ATA-2026-Unclassified-Report.pdf&quot;&gt;2026 Annual Threat Assessment&lt;/a&gt; makes clear that such actors exist, and that advances in biotechnology including synthetic biology and genomic editing &lt;em&gt;“could lead to novel biological threats.”&lt;/em&gt; It notes that several state actors likely maintain active offensive biological and chemical weapons programs—programs that could be accelerated by access to the raw capabilities of frontier AI models.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Because of our concerns about these “dual-use” capabilities (those that could be used for beneficial or harmful purposes, and where the line between them is not always easy to draw), we intentionally launched Fable 5 with almost all biology queries blocked. This enabled us to make the model available for users in other domains. We knew this would be frustrating for legitimate biology users: it would result in a high number of false positives in the near term, where users asking biology-related questions would have their requests blocked and sent to a less capable model. Nevertheless, we chose to make this tradeoff because the cost of Fable being misused in a dual-use domain like biology could potentially be &lt;a href=&quot;https://cdn.sanity.io/files/4zrzovbb/website/0bacdc8440ea96e62a8766d99ebe1d4eea6d5f3a.pdf&quot;&gt;catastrophic&lt;/a&gt;.&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;how-our-biology-safeguards-work&quot;&gt;How our biology safeguards work&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;One of the core ways we protect against misuse in biology is via safety &lt;em&gt;classifiers:&lt;/em&gt; smaller, automated AI systems that detect when Fable 5 is asked to perform a safeguarded biology task, or produce a harmful output (we&#39;ve &lt;a href=&quot;https://www.anthropic.com/news/fable-safeguards-jailbreak-framework&quot;&gt;previously written&lt;/a&gt; about our similar classifiers in the domain of cybersecurity).&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In the case of Fable 5, when a classifier fires, the model re-routes the user’s request to Opus 5, a capable model that does not have the same level of biological capability as Fable 5 and which cannot provide as much assistance to a malicious user. This is the fallback that users see when their requests are blocked.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Developing precise, robust classifiers is not a straightforward task. For a classifier to work rapidly and consistently, it has to learn the difference between what we consider “in scope” and “out of scope” for the topics and queries we consider to be potentially harmful. It takes time and iteration to tune the classifiers, avoiding both false positives (where classifiers fire on out-of-scope content) and false negatives (where in-scope content is missed). We also require our classifiers to be robust to attempts to bypass them (known as jailbreaks), which requires even further research and testing.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Starting with a very broad biology classifier meant that we could give our users access to Fable 5 while we continued our research aimed at refining it. The alternative—holding back the model until much more safeguards progress was made—would have delayed the model’s general access, and its potential benefits to our users, by weeks or months.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Over the past several weeks, we&#39;ve carefully rewritten the classifier’s constitution (which consists of a collection of rules to help the model discern between safeguarded and allowed content), taking care to carve out benign uses in detail. We solicited feedback on the changes from a diverse range of experts (both internal and external to Anthropic). We then developed updated training data for the classifier based on that constitution, and retrained it, and verified the new classifier would still generally trigger for harmful and dual-use research biology content but would now enable a wider range of benign and beneficial uses.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;As is illustrated in the diagram below, these updates meant that—compared to at the time of Fable 5’s launch—the classifier will trigger for many fewer benign biology-related requests.&lt;/p&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;3840&quot; height=&quot;1855&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/e6d3c7b32cc8a0798c0ad58a2340f846b3c8af42-3840x1855.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;em&gt;Illustration of our biology classifiers. Content that falls on the left-hand side of the classifier boundary is allowed; content that falls on the right-hand side is safeguarded (and is therefore blocked and sent instead to a less capable model);. Clearly harmful content (red), and content that is dual-use (orange), triggers the classifier and is blocked. We include a safety margin that includes content that is very likely benign but which is still blocked out of an abundance of caution (light green). Clearly benign content is in darker green.&lt;/em&gt;&lt;em&gt;Upon its launch, Fable 5 had very broad classifiers (A) that triggered on a wide range of requests—even ones that were almost certainly benign (those in the safety margin). The classifier boundary is thus very far to the left-hand side of the diagram. The update we are announcing today (B) means that many more benign requests are allowed by the classifier, which has become better at discerning subtle differences between benign and dual-use queries. The classifier boundary in the diagram has therefore moved further to the right-hand side.&lt;/em&gt;&lt;/figcaption&gt;&lt;/figure&gt;&lt;/div&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-4 post-heading&quot; id=&quot;conclusions&quot;&gt;Conclusions&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;There’s still much more to be done to refine our safeguards. There will inevitably remain false positives—requests that fall within the classifier’s safety margin where the request is very low-risk but where the classifier still fires. As we noted above, Fable will continue to block dual-use professional biology and drug development queries because of potential dual-use risk. We are fully committed to developing a safe, scalable path for researchers to use our most capable models via trusted access pathways.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We hope you’ll continue to share your feedback with us so we can improve our safeguards even further.&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__postFooter&quot;&gt;&lt;div class=&quot;PostDetail-module-scss-module__UQuRMa__footnotes&quot;&gt;&lt;h4 class=&quot;headline-5&quot;&gt;Footnotes&lt;/h4&gt;&lt;p&gt;&lt;sup&gt;1 &lt;/sup&gt;As a result, we expect the total number of fallbacks—for biology–related or any other reasons—will also be reduced: by roughly 67% on &lt;a href=&quot;http://claude.ai/&quot;&gt;Claude.ai&lt;/a&gt;, 55% on Cowork, 17% on Claude Code, and 7% on the Claude Platform.&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;</description><link>https://www.anthropic.com/news/improving-fable-5-s-biology-safeguards</link><guid isPermaLink="false">https://www.anthropic.com/news/improving-fable-5-s-biology-safeguards</guid><pubDate>Thu, 06 Aug 2026 16:00:00 GMT</pubDate></item><item><title>Mariano-Florentino (Tino) Cuéllar to join Anthropic as Chief Global Affairs Officer</title><description>&lt;article&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__hero&quot;&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper&quot;&gt;&lt;article&gt;&lt;div class=&quot;&quot;&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__body&quot; data-theme=&quot;ivory&quot;&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Mariano-Florentino (Tino) Cuéllar will join Anthropic as its first Chief Global Affairs Officer, leading the company’s work on policy, strategic international engagement, and government relationships worldwide.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Tino’s career spans law, technology, international security, and public institutions at the international, national, and state levels. He recently stepped down as President of the Carnegie Endowment for International Peace, a leading independent global policy research institution with scholars in 20 countries. Prior to his role at Carnegie, Tino was a Justice of the Supreme Court of California, where his opinions addressed technology and privacy, international agreements, and the separation of powers, among other issues. He was previously director of Stanford&#39;s Freeman Spogli Institute for International Studies, co-director of the university’s Center for International Security and Cooperation, and director of the Stanford Cyber Initiative. He has served on the President&#39;s Intelligence Advisory Board and the US Department of State&#39;s Foreign Affairs Policy Board, and worked in the White House and federal agencies in three presidential administrations. The National Academy of Sciences appointed him to its Committee on Responsible Computing Research.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In recent years, he also co-chaired the bipartisan Task Force on Nuclear Proliferation and American Security, co-led California’s Frontier AI Working Group, and served as board chair and later director of the Center for Advanced Study in the Behavioral Sciences. Currently, he is the Cameron Schrier Family Professor at Stanford Law School, where he started his teaching career before serving in the judiciary and began organizing classes on artificial intelligence nearly a decade ago. He also serves as Senior Fellow at Stanford’s Institute for Human-Centered Artificial Intelligence.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Tino has served as a Trustee of Anthropic&#39;s Long-Term Benefit Trust since January 2026. He has stepped down from the Trust to join the company. The Trust will select a successor under its normal process. &lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;“Policymakers in the US and around the world are increasingly realizing that we are at a critical inflection point when it comes to how we govern and develop artificial intelligence. The choices we make today will determine whether humanity can harness extraordinary possibilities to advance science and improve lives across the world or face enormous risk and growing inequality,” said Cuéllar. “Democracies must set the terms on which this technology advances, and there is no more consequential place to be shaping that work right now than Anthropic.”&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;“Tino has spent his career helping public institutions respond to times of change with thoughtfulness, pragmatism, and deep commitment to the common good,” said Daniela Amodei. “At all levels of government, the law, and academia, Tino has served with sound judgment and civic-mindedness, and we’re looking forward to him putting these principles to work at Anthropic. I can&#39;t think of anyone better prepared to partner with governments, civil society, and community groups as they engage with both the risks and opportunities presented by advanced AI.” &lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Tino arrives at a pivotal moment for Anthropic&#39;s work with governments around the world. The questions AI raises for economies, for security, and for communities absorbing rapid change are being debated by leaders everywhere. Ensuring AI’s trajectory is shaped by democratic societies and its benefits reach people broadly is a critical priority. Tino will help steer this work while finding common cause with heads of state and policy leaders on the questions and possibilities AI is raising for communities everywhere.&lt;br&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__postFooter&quot;&gt;&lt;/div&gt;&lt;/article&gt;</description><link>https://www.anthropic.com/news/tino-cuellar</link><guid isPermaLink="false">https://www.anthropic.com/news/tino-cuellar</guid><pubDate>Mon, 03 Aug 2026 16:00:00 GMT</pubDate></item><item><title>Investigating three real-world incidents in our cybersecurity evaluations</title><description>&lt;article&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__hero&quot;&gt;&lt;div class=&quot;PostDetail-module-scss-module__UQuRMa__illustrationHeroWrapper&quot;&gt;&lt;div class=&quot;Illustration-module-scss-module__WyGOtq__root Illustration-module-scss-module__WyGOtq__aspect-wide Illustration-module-scss-module__WyGOtq__padding-lg Illustration-module-scss-module__WyGOtq__radius-lg bg-heather&quot;&gt;&lt;div class=&quot;Illustration-module-scss-module__WyGOtq__inner&quot;&gt;&lt;img alt=&quot;Investigating three real-world incidents in our cybersecurity evaluations&quot; loading=&quot;lazy&quot; width=&quot;1000&quot; height=&quot;1000&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/d3dd09ad16c68461dc3fb01df5e84cf7ccafda6c-1000x1000.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper&quot;&gt;&lt;article&gt;&lt;div class=&quot;&quot;&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__body&quot; data-theme=&quot;ivory&quot;&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;strong&gt;&lt;em&gt;In a review of our cybersecurity evaluation transcripts, we found three incidents in which a Claude model reached the internet from within or while interacting with a third-party evaluation environment, and then gained unauthorized access to the real systems of three different organizations.&lt;/em&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;strong&gt;&lt;em&gt;Below we describe what happened, how it happened, and what we’re changing. We encourage other AI labs to perform similar reviews. This post reflects our current understanding; we&#39;ll update it if any details change.&lt;/em&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;strong&gt;&lt;em&gt;&lt;/em&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;On July 21, OpenAI &lt;a href=&quot;https://openai.com/index/hugging-face-model-evaluation-security-incident/&quot;&gt;disclosed&lt;/a&gt; that several of their models had broken out of an isolated test environment by exploiting a previously unknown (“zero-day”) vulnerability. The models went on to access the production infrastructure of Hugging Face, a platform for open-source machine learning models and AI datasets.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In response to this incident, we began a large-scale retrospective review of our own cybersecurity evaluations. In particular, we looked for evidence that Claude—like the OpenAI models that accessed Hugging Face—was able to access the internet from within testing environments that should have been sealed off.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;After reviewing 141,006 evaluation runs where Claude could have obtained internet access, we identified three incidents in which a model accessed the internet from within or while interacting with the evaluation environment of Irregular, one of our third-party evaluation partners, and then gained unauthorized access to the production infrastructure of three different organizations.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In all three incidents, Claude had been tasked with a capture-the-flag challenge, one of the ways we assess a model’s cyber capabilities. The model is given a fictional scenario and told that a piece of secret information (the “flag”) has been hidden on a different machine on the network, and its objective is to break in and retrieve it. The challenge is left open-ended, and no particular method is prescribed.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In all cases, Anthropic’s evaluation prompt specified to Claude that its environment was a simulation and that it had no internet access. Due to a misunderstanding between us and our evaluation partner, this was not the case, and internet access was available. Because of this, when Claude’s search led it to real systems on the open internet, it treated them as part of the exercise. (Cybersecurity evaluation ranges commonly include realistic details in order to accurately assess what models are capable of in real settings; a realistic-looking target would not itself be clear evidence to a model that the target is not part of a simulation.)&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Operating under the false belief that all accessible entities were intended to be in-scope for the exercise, Claude compromised the impacted organizations’ infrastructure using basic techniques, such as exploiting weak passwords and unauthenticated endpoints. It did not find or exploit any complex vulnerabilities, and in each case, Claude continued working to complete only the specific capture-the-flag task its evaluation had assigned. However, in some cases, our older model continued its attack even after getting evidence it was running on the open internet; our latest model stopped once it recognized it was on the internet. In none of these situations did Claude exfiltrate itself or deliberately attempt to escape its test environment.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;The incidents involved three different Claude models: Opus 4.7, Mythos 5, and an internal research test model.&lt;sup class=&quot;caption Body-module-scss-module__z40yvW__sup&quot;&gt;1&lt;/sup&gt; The earliest incidents date to April. The models in each of these evaluations ran without the standard safeguards we deploy when we make the model generally available (that is, they did not have the classifiers and monitoring we usually implement to prevent misuse). The models did, however, have their model-specific safety training (that is, they were not the “helpful-only” versions of the models that we sometimes use in testing). All the evaluations described here run on dedicated infrastructure, which is separate from and has no access to Anthropic’s sensitive internal systems or customer data.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We began our transcript review on Thursday, July 23, and stopped all cyber evaluations the same day after identifying transcripts where Claude may have accessed the internet. We identified all three incidents the next day. We notified our evaluation partner Irregular and the three affected organizations on Monday, July 27. The two organizations we were able to reach had not previously detected the activity or contacted us, and we are now working with them to remediate. We are continuing to reach out to the third.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We conducted this review in collaboration with &lt;a href=&quot;https://www.irregular.com/research/next-generation-of-cyber-evals&quot; target=&quot;_blank&quot; rel=&quot;noopener noreferrer&quot;&gt;Irregular&lt;/a&gt;. We’re grateful to them for working closely with us to understand and resolve these incidents; they are also conducting their own investigation. We believe this type of collaboration is increasingly critical to ensuring safe, rigorous evaluation of models. We look forward to our joint work on security.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In what follows, we provide more details on each incident and how we’re responding moving forward.&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;background-on-cyber-evaluations&quot;&gt;&lt;strong&gt;Background on cyber evaluations&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We regularly run cybersecurity evaluations that involve simulating real offensive cybersecurity challenges. These evaluations are a critical step in developing and releasing models—a nuanced understanding of model capabilities allows us to design appropriate safeguards and ultimately release models safely.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We began running cybersecurity evaluations in February 2025 with Claude Sonnet 3.7 on &lt;a href=&quot;https://cybench.github.io/&quot; target=&quot;_blank&quot; rel=&quot;noopener noreferrer&quot;&gt;Cybench&lt;/a&gt;, which consisted of 40 different capture-the-flag challenges. Over time, we’ve increased the number of benchmarks we use as new ones are released and model capabilities evolve. In the &lt;a href=&quot;https://www-cdn.anthropic.com/d00db56fa754a1b115b6dd7cb2e3c342ee809620.pdf&quot; target=&quot;_blank&quot; rel=&quot;noopener noreferrer&quot;&gt;Mythos 5 System Card&lt;/a&gt;, for example, we included CyberGym and ExploitBench, benchmarks that evaluate the ability of language models to find novel vulnerabilities.&lt;sup class=&quot;caption Body-module-scss-module__z40yvW__sup&quot;&gt;2&lt;/sup&gt; In most of these evaluations, the environments are not connected to the internet, and the model is told as much.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We frequently work with external partners who create and assist in running some of these cybersecurity evaluations. External partners offer environments and scenarios more diverse than we could build alone, and provide independent, third-party assessments of our models.&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;what-happened&quot;&gt;&lt;strong&gt;What happened&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Of the 141,006 evaluation runs we reviewed, we identified three separate incidents (involving six total runs, four of which impacted the same organization; the other two incidents each happened in independent evaluation runs). Each incident involved a different fictional capture-the-flag scenario—for example, in one, Claude played an employee of a made-up company, attacking that company’s internal systems inside a private test environment.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In all cases, our evaluation prompt stated explicitly that Claude had no internet access, but didn’t give Claude any limits on where to look for the flag. However, a misconfiguration left the machines that Claude accessed as part of the evaluation with live internet access. Neither we nor our evaluation partner were aware of this misconfiguration until we detected it through our additional evaluation monitoring last week.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Several defense-in-depth measures, on both our side and our partner’s, could have prevented these incidents, or at least reduced their likelihood of occurring. Careful validation of all internet access paths before evaluations began and real-time monitoring of the evaluation logs would have helped to surface the problem sooner. Both we and our partner also could have reviewed evaluation transcripts or network logs more thoroughly. It’s also possible that a prompt which told Claude it &lt;em&gt;did &lt;/em&gt;have internet access would have changed how Claude behaved when it came into contact with real systems.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Claude did what capture-the-flag exercises train cyber experts to do: look for ways to reach the flag. That search led it to discover that its machine could reach the internet, but having been told in the system prompt that there was no internet access, Claude believed everything it initially encountered was part of the simulation, and treated the real systems it found as pieces of the exercise. The three incidents involved three different models, and each responded differently once signs emerged that the targets were real, as we describe below.&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;incident-1&quot;&gt;&lt;strong&gt;Incident 1&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In one evaluation, the fictional target company chosen by our evaluation partner shared a name with an active website domain name. This evaluation container had unintended direct internet access, due to the misunderstanding discussed above.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In four runs of this evaluation, Claude ran into difficulty reaching its simulated target within the evaluation environment, but then discovered that the real company was reachable via the internet. Assuming this was the intended target in the capture-the-flag task, Claude sought, identified, and exploited vulnerabilities within the company’s infrastructure, believing it to be part of the exercise. These four runs extracted information like application and infrastructure credentials, and obtained access to a database containing several hundred rows of production data. This represented the most serious impact we identified.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;This incident involved Claude Opus 4.7, and was the only case in which the model continued to attack a system after learning it was likely operating in a real environment. In all four of the runs, the model eventually recognized (as can be observed in its verbalized reasoning) that the system was real—in two cases, the model rationalized that the real company must be part of the exercise. However, none stopped the attack on that basis.&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;incident-2&quot;&gt;&lt;strong&gt;Incident 2&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In another evaluation, Claude found a document inside the fictional environment that appeared to be another made-up company’s setup instructions for new developers. Those instructions told employees to install a Python package from PyPI—the public registry where Python software is published—that did not actually exist.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Claude spotted this as a potential opening: if it published its own package under the same name, the fictional company’s systems would download and install it automatically. So, Claude built and published a malicious (essentially booby-trapped) Python package with the same name in an attempt to win the capture-the-flag challenge.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Claude went to extensive lengths to carry out this attack—lengths that would likely have indicated to a human participant that this was no longer just an evaluation, and that they were in fact uploading a real PyPI package. For instance, in one case, in order to create a PyPI account, Claude needed an email address. And in order to create an email address, it needed a phone number. To get a phone number, after failing to find a free phone number service, it tried—and failed—to obtain funds to pay for a phone number through several different means. It finally backtracked, found a free, non-blocked email provider, used this to register a PyPI account, and then used this account to upload malware to PyPI.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Claude believed the package registry it was using to be part of the simulation, but in reality the package was made freely available online for roughly one hour. During that window, the package was downloaded and run on 15 real systems. One of these systems was a scanner belonging to a real security company (separate from the fictional company introduced in the scenario) that routinely installs Python packages and scans them for malware. When that company’s scanner installed the package, Claude’s hidden code executed. We believe the company’s security scanner treated PyPI packages as safe to install, and as a result, Claude was able to exfiltrate the company’s credentials to a collection point it had set up. Claude then used these credentials to access further infrastructure from this company.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Claude didn’t directly target this company—it did not even know the company existed when it uploaded the package. But because the code was published to the open internet, it impacted any system that ran it. (The package that Claude uploaded was automatically removed from PyPI by PyPI’s own security systems. We’ve notified the PyPI team of this incident, and provided them with the relevant indicators.)&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;This attack was carried out by Claude Mythos 5. Early in the run, Claude’s own reasoning correctly identified the consequences of its actions. It noted that if this were the real internet, publishing the package would be a real-world attack—“NOT okay, and surely not the intended solution.” However, it convinced itself it was still in a simulation on the grounds that it didn’t recognize the (in reality genuine) certificate authorities securing its connections. In addition, the calendar date of 2026 on the systems proved, according to Claude, that the environment was staged. Claude never revisited this conclusion; when automated scanners began installing the package, for example, Claude took them to be scripted actors within the evaluation.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;It is our view that, regardless of what it believed about its environment, the lengths Claude went to in order to publish the PyPI package fall short of ideal behavior, and this is an area where we will focus more training.&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;incident-3&quot;&gt;&lt;strong&gt;Incident 3&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In this evaluation, when Claude was unable to reach its intended fictional target, it looked for alternatives online, scanning roughly 9,000 targets. It eventually found and compromised one company’s internet-facing application, using basic and well-known cyberattack techniques like reading credentials from an exposed debug page and SQL injection.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;This attack was carried out by an internal research test model. For most of the run, Claude treated the (real) hosts it reached as just parts of the exercise; it assumed them to be simulated and believed its actions were therefore harmless. However, later in the run, Claude realized that the compromised host sat in a cloud account with no connection to the capture-the-flag challenge. On its own, it concluded that the target was in fact real, and ceased its attack.&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;our-analysis-of-claudes-behavior&quot;&gt;&lt;strong&gt;Our analysis of Claude’s behavior&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;In each of these cases, Claude was explicitly told by our prompt that it had no internet access. Through most of each run, as it encountered real-world systems, Claude assumed these to be parts of the exercise (though it sometimes recognized they were real production systems). And because a capture-the-flag scenario is by design an instruction to attack an external system, doing so was in line with the task Claude had been given.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Against this shared backdrop, the three models behaved differently once signs emerged that their targets were real. Opus 4.7, our oldest model, recognized that it had reached production systems but continued its attack. Mythos 5 correctly intuited that it was accessing the open internet, but reasoned its way back to the conclusion that it was still in a simulation. Our latest model, an internal research test model, also considered whether its targets were in fact real. When evidence emerged that they were, it stopped the exercise.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;These are three isolated incidents and were not part of a controlled, experimental comparison. We must therefore be cautious about drawing conclusions from them. Still, the behavior we most want to see—recognizing that a target is real and stopping without being prompted—occurred only in the most recent of the three models (and even that model went further before stopping than we would want). The pattern is consistent with more advanced models responding more appropriately, but we would need to perform more testing to be confident in this conclusion.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We are also in dialogue with METR, an independent AI evaluation organization, to conduct a third-party review, including access to all transcripts and sampling access to the relevant models. In the meantime, within the next week, we will release a lightly redacted transcript in which Claude built a malicious PyPI package. To protect the organizations affected, we are unable to release more transcripts at this time, but will work to make these available once we are able.&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;how-were-responding&quot;&gt;&lt;strong&gt;How we’re responding&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We draw several lessons from these incidents.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;First, evaluation environments that involve powerful autonomous capabilities &lt;em&gt;also&lt;/em&gt; require significant controls. Safety testing happens before a model is released precisely because we don’t yet know what it is capable of. Evaluation environments increasingly need to be held to the same security standard as any other system our models run in.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;A cyber evaluation range that contains only fictional scenarios may appear to be low-risk—after all, nothing inside them is real. However, we need to change how we model such threats as AI capabilities advance. Advanced agents in environments without access to sensitive information nevertheless present a substantial threat on their own. We need to better co-design evaluation environments, and do better monitoring of evaluation results, to meet this threat. Some of the solutions here may even be simple fixes; it’s likely, for instance, that Claude wouldn’t have accessed the internet to begin with if the prompt had clearly explained which systems were in and out of scope for the evaluation.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;This applies not only to internal environments but to third-party vendors as well—the infrastructure built by evaluation vendors requires the same increased monitoring and hardening. We encourage other labs to perform similar reviews. Additionally, the field would benefit from a broader conversation about how to evaluate increasingly powerful AI agents both safely &lt;em&gt;and&lt;/em&gt; realistically, including how to weigh the realism provided by internet access during pre-deployment testing against the risks it introduces.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Second, the line between an aligned action and a harmful one is dependent on the model’s understanding of its situation. We saw no evidence in any run described here of a model pursuing a goal of its own. Instead, the models did what their evaluation asked—though in most cases, they did so while holding a false belief about whether the environment was real. In the runs where the model recognized the system as real &lt;em&gt;and kept going&lt;/em&gt;, it did so because it assumed that to be part of the challenge. Situational awareness is one factor that allows the model to make aligned decisions, but in this case, Claude’s was wrong.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Finally, these incidents demonstrate the importance of defense-in-depth approaches. We run capability evaluations like these without safeguards that ship with our generally available models because our goal is to measure what the underlying model can do. That is safe only if the evaluation is appropriately contained. However, the safeguards deployed on our generally available models would have blocked the behaviors identified.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Ultimately, many factors contributed to these incidents, but, consistent with a blameless postmortem culture, we’re approaching the fixes as if the responsibility were ours alone. This begins with ensuring every part of our evaluation pipeline is secure, including the manner in which we integrate with external partners. Moving forward, it will include expanding our continuous monitoring of evaluation transcripts for unexpected behavior, improving our investigation tooling, and conducting more rigorous assurance work with the vendors we rely on.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We began this review after OpenAI disclosed that its models had escaped an isolated test environment, and we commend them for publishing &lt;a href=&quot;https://openai.com/index/hugging-face-model-evaluation-security-incident/&quot;&gt;their report&lt;/a&gt;. While we also found evidence of our models reaching systems they weren’t supposed to reach, the incidents are otherwise quite different:&lt;/p&gt;&lt;ul class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;li&gt;We discovered these incidents after a proactive review of our cybersecurity evaluation transcripts; the affected organizations had not detected the activity, and we have subsequently reached out to all three.&lt;/li&gt;&lt;li&gt;Whereas OpenAI’s models exploited a novel vulnerability to escape isolation, the Claude models evaluated here accessed the internet via an open path.&lt;/li&gt;&lt;li&gt;While there is not a perfectly sharp distinction between the two, we believe these incidents to be closer to a harness and operational failure than a model alignment failure. Our models were told they had no internet access and to capture the flag, while in fact being misconfigured to have internet access. This led them to believe—arguably reasonably—that the real environments they encountered were simulations.&lt;/li&gt;&lt;li&gt;Notably, our most recent model, on realizing that it was working in a real environment, stopped its pursuit of the evaluation goal.&lt;/li&gt;&lt;/ul&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;These facts give us cautious optimism that with tighter monitoring and controls around evaluation infrastructure, as well as continued investment in alignment, this type of risk can be overcome.&amp;nbsp;&lt;br&gt;&lt;br&gt;&lt;em&gt;Updated Aug 3: &lt;/em&gt;Corrected the name of the evaluation in which the OpenAI/Hugging Face incident occurred.&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__postFooter&quot;&gt;&lt;div class=&quot;PostDetail-module-scss-module__UQuRMa__footnotes&quot;&gt;&lt;h4 class=&quot;headline-5&quot;&gt;Footnotes&lt;/h4&gt;&lt;ol&gt;&lt;li id=&quot;footnote-1&quot;&gt;We routinely test internal research prototypes like this one. It is not planned for general release.&lt;/li&gt;&lt;li id=&quot;footnote-2&quot;&gt;We generally store traces for benchmark evaluations. We have carefully audited these two benchmarks in particular for signs of harm because the OpenAI/Hugging Face incident occurred during an evaluation of ExploitGym.&lt;/li&gt;&lt;/ol&gt;&lt;p&gt;&lt;br&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;</description><link>https://www.anthropic.com/news/investigating-incidents-cybersecurity-evals</link><guid isPermaLink="false">https://www.anthropic.com/news/investigating-incidents-cybersecurity-evals</guid><pubDate>Wed, 29 Jul 2026 16:00:00 GMT</pubDate></item><item><title>Our position on open-weights models</title><description>&lt;article&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__hero&quot;&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper&quot;&gt;&lt;article&gt;&lt;div class=&quot;&quot;&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__body&quot; data-theme=&quot;ivory&quot;&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;em&gt;A post by Dario Amodei, Anthropic CEO&lt;/em&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Over the last few days there has been a lot of discussion about open-weights models, especially those from China. Reports suggest that some US officials are &lt;a href=&quot;https://www.axios.com/2026/07/20/ai-us-china-open-source-kimi&quot;&gt;considering banning&lt;/a&gt; the use of Chinese open-weights models by US companies. In response, many tech companies have signed &lt;a href=&quot;https://x.com/JensenHuang/status/2080643682408321103&quot;&gt;a letter&lt;/a&gt; supporting open-weights models, and some people have even accused Anthropic of wanting to ban open-weights models as a means of protecting our business. Anyone who has read my past writing should know that I don’t regard such bans as a useful measure, but let me state it clearly so that there is no doubt: &lt;strong&gt;Anthropic has never advocated for a ban on open-weights models.&lt;/strong&gt;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Open-weights models that don’t have dangerous capabilities are a public good: they don’t cost anything besides the compute needed to run them, and they provide value to businesses, developers, and researchers.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Protectionist bans would not address my most serious national security concerns. Specifically, I am worried about two nightmare scenarios. I laid these out in my essay &lt;a href=&quot;https://darioamodei.com/essay/the-adolescence-of-technology&quot;&gt;&lt;em&gt;The Adolescence of Technology&lt;/em&gt;&lt;/a&gt; six months ago&lt;sup class=&quot;caption Body-module-scss-module__z40yvW__sup&quot;&gt;1&lt;/sup&gt;, and have held these positions consistently for many years:&lt;/p&gt;&lt;ol class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;li&gt;My primary concern is the risk that authoritarian governments—not solely the Chinese Communist Party (CCP), although the CCP is clearly the most capable threat—build AI models that are more powerful than those built by the US, and use them to achieve permanent military superiority or perpetrate incredibly deep repression of their own people. This concern is widely shared within the US government: Vice President Vance &lt;a href=&quot;https://www.presidency.ucsb.edu/documents/remarks-the-vice-president-the-artificial-intelligence-action-summit-paris-france&quot;&gt;warned&lt;/a&gt; in Paris last year that “authoritarian regimes have stolen and used AI to strengthen their military, intelligence, and surveillance capabilities,” and the Intelligence Community’s &lt;a href=&quot;https://www.dni.gov/files/ODNI/documents/assessments/ATA-2026-Unclassified-Report.pdf&quot;&gt;2026 Annual Threat Assessment&lt;/a&gt; found that “other global powers’ robust progress in AI is challenging US economic competitiveness and national security advantages.” It is irrelevant whether these models are released with open weights, and certainly irrelevant whether they are used by US businesses. In fact, the most dangerous model may be one that is trained in secret and handed only to the People’s Liberation Army for use in drones and the Ministry of State Security for surveillance and repression.&lt;/li&gt;&lt;li&gt;My secondary concern is the risk that powerful AI models may be misused to carry out cyberattacks or biological attacks, and may have &lt;a href=&quot;https://time.com/article/2026/07/24/openai-hugging-face-attack/&quot;&gt;serious alignment problems&lt;/a&gt;. Open-weights models—it does not matter whether they come from China or anywhere else—do potentially present a higher risk than closed models, because it is very difficult to apply guardrails to them or monitor their usage, and once weights are released they cannot be withdrawn&lt;sup class=&quot;caption Body-module-scss-module__z40yvW__sup&quot;&gt;2&lt;/sup&gt;. But banning the use of these models by US businesses does nothing to address this risk, because bad actors are unlikely to be legitimate US businesses. It &lt;em&gt;would&lt;/em&gt; protect US AI companies from competition, but that has never been my goal.&lt;/li&gt;&lt;/ol&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;To address these concerns, I &lt;em&gt;do&lt;/em&gt; support the following three measures, which I and Anthropic have consistently advocated for:&lt;/p&gt;&lt;ul class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;li&gt;&lt;strong&gt;We should not sell powerful chips or chipmaking equipment to China&lt;/strong&gt;, and we should crack down on the rampant &lt;a href=&quot;https://www.justice.gov/opa/pr/three-charged-conspiring-unlawfully-divert-cutting-edge-us-artificial-intelligence&quot;&gt;smuggling&lt;/a&gt;&lt;sup class=&quot;caption Body-module-scss-module__z40yvW__sup&quot;&gt;3&lt;/sup&gt; and workarounds used to obtain access to such chips. China has limited domestic production capacity, and therefore, due to the &lt;a href=&quot;https://arxiv.org/abs/2001.08361&quot;&gt;scaling laws&lt;/a&gt;, cannot build more powerful models than the US without US chips. This is the most efficient and direct way to block threat #1, and by hampering the training of models that are out of reach of US law, it also indirectly helps with threat #2.&lt;/li&gt;&lt;li&gt;&lt;strong&gt;We should crack down on industrial-scale &lt;a href=&quot;https://www.anthropic.com/news/detecting-and-preventing-distillation-attacks&quot;&gt;distillation operations&lt;/a&gt;.&lt;/strong&gt; Distillation is a much more compute-efficient process than training models from scratch. It allows China to build much better models than its number of chips would ordinarily enable, and thus partially evade chip bans. Distillation does not allow the CCP to obtain equivalent or superior AI capabilities to the US, but it can bring the Chinese frontier to within a &lt;a href=&quot;https://www.anthropic.com/research/2028-ai-leadership&quot;&gt;few months &lt;/a&gt;of the US frontier. It is true that many of the companies carrying out these operations release open-weights models—but the open weights are far less relevant than the fact that the operations are backed by an authoritarian state seeking to overtake the US at the frontier. We should have policy interventions to deter this behavior. A blanket ban on open-weights models is neither the correct remedy nor something we have called for&lt;sup class=&quot;caption Body-module-scss-module__z40yvW__sup&quot;&gt;4&lt;/sup&gt;.&lt;/li&gt;&lt;li&gt;&lt;strong&gt;All sufficiently capable models, open and closed, should go through mandatory safety testing.&lt;/strong&gt; The best way to address threat #2 is to just directly test models for cyber, biological, and alignment risks before release. I think this idea is actually close to a consensus: I have been heartened both that the Trump administration has moved in this direction in recent months, and by &lt;a href=&quot;https://demishassabis.substack.com/p/a-framework-for-frontier-ai-and-the-dawning-of-a-new-age&quot;&gt;recent industry proposals&lt;/a&gt; that would apply such testing to the most capable models regardless of their country of origin or whether they are open or closed (while exempting less capable models, such as those from startups and academia, entirely). Whether open models do or don’t pose an increased risk, and whether that risk can be mitigated, is something that should emerge from testing, rather than be decided in advance—and there may be promising methods for improving the safety of open-weights models, including recent research from AE Studio and Anthropic on &lt;a href=&quot;https://alignment.anthropic.com/2026/modular-pretraining/&quot;&gt;modular training strategies&lt;/a&gt;. Note that to be effective, testing would need to be global, which means even the CCP would need to be on board. I think this may actually be possible: as I wrote in &lt;em&gt;The Adolescence of Technology&lt;/em&gt;, limited cooperation around preventing AI biological weapons may be possible because it is in China’s interest too.&lt;/li&gt;&lt;/ul&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;This brings me to the &lt;a href=&quot;https://images.nvidia.com/pdf/Open-Weights-and-American-AI-Leadership.pdf&quot;&gt;open letter&lt;/a&gt;. I agree with much of it: open weights expand access to the AI economy, they strengthen competition at least for some use cases, and they give customers greater control. Concerns about distillation should be addressed through targeted legal and commercial frameworks—the same measure I described above. But I don’t agree with the letter’s assertions that open-weights models necessarily make it easier to develop safeguards or that broad access to capabilities necessarily helps defenders more than attackers. It seems at least as likely to me that the opposite will be true. For example, I worry that biology will have a strong attacker-defender asymmetry, where sufficiently capable models may be able to quickly weaponize pandemic-level viruses with widely available materials, whereas defense against these agents is a multi-year operational task in the best case (as we saw with Operation Warp Speed)&lt;sup class=&quot;caption Body-module-scss-module__z40yvW__sup&quot;&gt;5&lt;/sup&gt;. Questions like this should be empirically answered by rigorous pre-release testing, not assumed in advance.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;To summarize my and Anthropic’s position, we have not and are not advocating for a ban on open-weights models as a category. We should instead focus on keeping powerful chips out of authoritarian hands, stopping industrial-scale distillation, and requiring safety testing of all sufficiently capable models, open and closed.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;em&gt;*Edit 28 July: Updated to note that the cited research on modular training strategies was a collaboration between Anthropic and &lt;a href=&quot;https://ae.studio/&quot;&gt;AE Studio&lt;/a&gt;.&lt;/em&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__postFooter&quot;&gt;&lt;div class=&quot;PostDetail-module-scss-module__UQuRMa__footnotes&quot;&gt;&lt;h4 class=&quot;headline-5&quot;&gt;Footnotes&lt;/h4&gt;&lt;ol&gt;&lt;li id=&quot;footnote-1&quot;&gt;See Sections 3 and 2 of that essay for discussion of misuse for seizing power and discussion of biological risks, respectively.&lt;/li&gt;&lt;li id=&quot;footnote-2&quot;&gt;See &lt;a href=&quot;https://www.aisi.gov.uk/blog/how-far-behind-the-frontier-are-leading-open-weight-models-on-cyber&quot;&gt;this report&lt;/a&gt; from the UK AI Security Institute, specifically: “The same openness underpinning these benefits precludes many of the safety measures that closed model developers can use to detect and disrupt misuse, iterate on safeguards as vulnerabilities emerge, control user access and withdraw models. Once open-weight models are released, these options are lost permanently: safeguards can be removed, and copies can be downloaded, redistributed, and run on private systems beyond monitoring. For models with dangerous capabilities – including highly cyber-capable models – open weight release therefore creates a persistent and irreversible risk of misuse.”&lt;/li&gt;&lt;li id=&quot;footnote-3&quot;&gt;See also &lt;a href=&quot;https://www.justice.gov/opa/pr/chinese-national-and-two-us-citizens-charged-conspiring-smuggle-artificial-intelligence&quot;&gt;here&lt;/a&gt;, &lt;a href=&quot;https://www.justice.gov/opa/pr/us-citizens-and-chinese-nationals-arrested-exporting-artificial-intelligence-technology&quot;&gt;here&lt;/a&gt;, and &lt;a href=&quot;https://www.justice.gov/opa/pr/us-authorities-shut-down-major-china-linked-ai-tech-smuggling-network&quot;&gt;here&lt;/a&gt; for more reports from the US Department of Justice.&lt;/li&gt;&lt;li id=&quot;footnote-4&quot;&gt;At Anthropic we’re committed to cracking down on industrial-scale distillation through our own practices, including identifying and banning accounts that use our models in this way. This is challenging—for instance, the relevant accounts can often only be identified &lt;em&gt;after&lt;/em&gt; substantial distillation has occurred, and distillation often involves creating large numbers of fake accounts that form a moving target. The practices of any individual company cannot entirely solve the problem, which is why we have called for policy on this issue.&lt;/li&gt;&lt;li id=&quot;footnote-5&quot;&gt;See &lt;a href=&quot;https://darioamodei.com/essay/the-adolescence-of-technology#2-a-surprising-and-terrible-empowerment&quot;&gt;Section 2 of &lt;em&gt;The Adolescence of Technology&lt;/em&gt;&lt;/a&gt;&lt;em&gt; &lt;/em&gt;for a more detailed discussion of biological threats and the offense-defense balance. To summarize, what I believe currently keeps us safe in biology is not “defenders”, or even the availability of materials, but a negative correlation between intellectual capability and desire to commit catastrophic harm. Previous technologies like internet search or even DNA synthesis were nowhere near powerful enough to break this correlation, but I worry that at its current rate of progress, AI will do so very soon. Another way to say it is that a sufficiently powerful technology removes all barriers and exposes whether the attacker or defender has an inherent structural advantage, and I worry in biology it is the attacker.&lt;/li&gt;&lt;/ol&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;</description><link>https://www.anthropic.com/news/position-open-weights-models</link><guid isPermaLink="false">https://www.anthropic.com/news/position-open-weights-models</guid><pubDate>Sun, 26 Jul 2026 16:00:00 GMT</pubDate></item><item><title>Cognizant and Anthropic expand their partnership to bring Claude to enterprise clients</title><description>&lt;article&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__hero&quot;&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper&quot;&gt;&lt;article&gt;&lt;div class=&quot;&quot;&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__body&quot; data-theme=&quot;ivory&quot;&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We&#39;re expanding our &lt;a href=&quot;https://www.anthropic.com/news/cognizant-partnership&quot;&gt;partnership&lt;/a&gt; with &lt;a href=&quot;https://www.cognizant.com/&quot;&gt;Cognizant&lt;/a&gt;, one of the world&#39;s largest technology services companies.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Cognizant uses Claude in the systems it builds and runs for clients across manufacturing, life sciences, insurance, and other industries. With the expansion of our partnership, it’s embedding Claude across its own business and engineering platforms, scaling a Claude-certified workforce as part of its new Frontier Certified workforce model, and becoming a Global Premier Partner in the &lt;a href=&quot;https://claude.com/partners&quot;&gt;Claude Partner Network&lt;/a&gt;.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Successfully integrating AI into a large enterprise requires knowledge of the company&#39;s industry, the systems it already runs on, and the rules it operates under. Cognizant brings that domain context, along with the engineering depth and delivery scale to bring Claude to enterprises worldwide.&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;cognizant-builds-with-claude&quot;&gt;&lt;strong&gt;Cognizant builds with Claude&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Cognizant&#39;s engineers build with Claude every day, and more than 30,000 associates have completed Claude training.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Cognizant is embedding Claude across several of its platforms, including Flowsource™, Neuro® AI Engineering, and Neuro® IT Ops. Flowsource, its full-stack engineering platform, now runs Claude Code alongside software engineers in its Spec-Driven Development module. Flowsource directs Claude Code using the specifications, coding standards, and architectural blueprints a project defines, then and then evaluates the output before production.&lt;/p&gt;&lt;h3 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-6 post-subsection&quot; id=&quot;cognizant-puts-claude-to-work-for-clients&quot;&gt;&lt;strong&gt;Cognizant puts Claude to work for clients&lt;/strong&gt;&lt;/h3&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;The company uses what it learns internally to shape how it brings Claude to clients, and that work is already underway. Examples of what its teams built include:&lt;/p&gt;&lt;ul class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;li&gt;A customer experience portal for a global manufacturer within six months of kickoff.&lt;/li&gt;&lt;li&gt;An agentic contract-intelligence system for a biopharmaceutical company that has helped cut contract review time by up to 40 percent while lifting extraction accuracy above 88 percent in that deployment.&lt;/li&gt;&lt;li&gt;A risk-navigation tool that has helped underwriters evaluate accounts, which once took hours of manual research, in minutes—saving each person roughly eight hours a week in that deployment.&lt;/li&gt;&lt;/ul&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&quot;AI capability is rising faster than enterprises can absorb it, and that gap is the defining problem of this moment,&quot; said Ravi Kumar S, Chief Executive Officer of Cognizant. &quot;Our role is to be the bridge. We bring the industry context, the engineering scale and the trust frameworks that use Claude to deliver production outcomes inside the most demanding enterprise environments. This partnership with Anthropic is about doing that for clients who need AI they can rely on, not just experiment with.&quot;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&quot;Deepening our partnership with Cognizant will help more companies harness AI&#39;s growing capability and deploy it in real, practical ways for their businesses,&quot; said Daniela Amodei, Co-Founder and President of Anthropic. &quot;From manufacturing to the life sciences, Cognizant is bringing Claude into the everyday work of some of the world&#39;s most demanding industries—the kinds of contexts where AI can demonstrate its greatest value for humanity.&quot;&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;To learn more about the Claude Partner Network, visit &lt;a href=&quot;https://www.anthropic.com/partners&quot;&gt;anthropic.com/partners&lt;/a&gt;.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;br&gt;&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__postFooter&quot;&gt;&lt;/div&gt;&lt;/article&gt;</description><link>https://www.anthropic.com/news/cognizant-anthropic</link><guid isPermaLink="false">https://www.anthropic.com/news/cognizant-anthropic</guid><pubDate>Sun, 26 Jul 2026 16:00:00 GMT</pubDate></item><item><title>Introducing Claude Opus 5</title><description>&lt;article&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__hero&quot;&gt;&lt;div class=&quot;PostDetail-module-scss-module__UQuRMa__illustrationHeroWrapper&quot;&gt;&lt;img alt=&quot;Introducing Claude Opus 5&quot; width=&quot;2880&quot; height=&quot;1620&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;PostDetail-module-scss-module__UQuRMa__heroImage&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/54b7ab1d2c2521f83ae5d2da5f9d99321c370d24-2880x1620.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper&quot;&gt;&lt;article&gt;&lt;div class=&quot;&quot;&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__body&quot; data-theme=&quot;ivory&quot;&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Claude Opus 5 is available today. It’s a thoughtful and proactive model that comes close to the frontier intelligence of Claude Fable 5 at half the price.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;On coding and knowledge work evaluations like &lt;a href=&quot;https://www.frontierbench.ai/&quot;&gt;Frontier-Bench&lt;/a&gt; and &lt;a href=&quot;https://artificialanalysis.ai/evaluations/gdpval-aa&quot;&gt;GDPval-AA&lt;/a&gt;, Opus 5 is the new state-of-the-art, though it remains behind Mythos 5 on cybersecurity tasks.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Opus 5 is designed to be used every day: it works more efficiently than other models. It’s the new default model on Claude Max, and the strongest model on Claude Pro.&lt;/p&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;eager&quot; width=&quot;2600&quot; height=&quot;2578&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/a8fb4f77a9fe240e6f27f3bdc47a137f3c74a29d-2600x2578.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/figure&gt;&lt;/div&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;performance-and-cost-effectiveness&quot;&gt;Performance and cost-effectiveness&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Claude Opus 5 provides greatly improved performance for the same cost as its predecessor, Opus 4.8. The charts in this section show how performance changes according to the model’s effort setting, which customers can use to optimize for intelligence or conserve tokens for faster and cheaper results.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Opus 5 excels on valuable software engineering tasks. For example, on &lt;strong&gt;Frontier-Bench v0.1, &lt;/strong&gt;Opus 5 surpasses all other models, and more than doubles Opus 4.8’s performance at a lower cost per task. On &lt;strong&gt;CursorBench 3.2&lt;/strong&gt;, at max effort, the model performs within 0.5% of Fable 5’s peak score, but at half the cost per task; it also achieves greater performance at a given cost than all other models on high, xhigh, and max effort.&lt;/p&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column&quot;&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-carousel&quot;&gt;&lt;div class=&quot;Tabs-module-scss-module__iIvFzq__tab-container&quot; role=&quot;tablist&quot; aria-label=&quot;Media carousel tabs&quot;&gt;&lt;button role=&quot;tab&quot; aria-selected=&quot;true&quot; aria-controls=&quot;panel-media-0&quot; id=&quot;tab-media-0&quot; class=&quot;Tabs-module-scss-module__iIvFzq__tab Tabs-module-scss-module__iIvFzq__active&quot;&gt;&lt;span class=&quot;caption&quot;&gt;Frontier-Bench v0.1&lt;/span&gt;&lt;/button&gt;&lt;button role=&quot;tab&quot; aria-selected=&quot;false&quot; aria-controls=&quot;panel-media-1&quot; id=&quot;tab-media-1&quot; class=&quot;Tabs-module-scss-module__iIvFzq__tab&quot;&gt;&lt;span class=&quot;caption&quot;&gt;CursorBench&lt;/span&gt;&lt;/button&gt;&lt;button role=&quot;tab&quot; aria-selected=&quot;false&quot; aria-controls=&quot;panel-media-2&quot; id=&quot;tab-media-2&quot; class=&quot;Tabs-module-scss-module__iIvFzq__tab&quot;&gt;&lt;span class=&quot;caption&quot;&gt;AA Coding Agent Index&lt;/span&gt;&lt;/button&gt;&lt;/div&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-container&quot;&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-panel MediaCarousel-module-scss-module__S2ancq__active&quot; role=&quot;tabpanel&quot; id=&quot;media-panel-0&quot; aria-labelledby=&quot;media-tab-0&quot; aria-hidden=&quot;false&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;eager&quot; width=&quot;3840&quot; height=&quot;2160&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/7530b1086992936d7e9d5796a892d1e8fa063253-3840x2160.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/figure&gt;&lt;/div&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-panel&quot; role=&quot;tabpanel&quot; id=&quot;media-panel-1&quot; aria-labelledby=&quot;media-tab-1&quot; aria-hidden=&quot;true&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;eager&quot; width=&quot;3840&quot; height=&quot;2160&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/1af9dbd742e3812be4bf66903740188fb8fd2e33-3840x2160.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/figure&gt;&lt;/div&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-panel&quot; role=&quot;tabpanel&quot; id=&quot;media-panel-2&quot; aria-labelledby=&quot;media-tab-2&quot; aria-hidden=&quot;true&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;eager&quot; width=&quot;3840&quot; height=&quot;2160&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/08499ed7c3c2b6416700fa47c70d36dff5eb8461-3840x2160.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/figure&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;We see similar results on knowledge work and problem-solving tasks. For example:&lt;/p&gt;&lt;ul class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;li&gt;On &lt;strong&gt;ARC-AGI 3&lt;/strong&gt;, an evaluation where the model has to solve novel problems, Opus 5’s score is three times as high as the next-best model.&lt;/li&gt;&lt;li&gt;On &lt;strong&gt;Zapier AutomationBench&lt;/strong&gt;, which measures whether models can complete business tasks from start to finish, Opus 5’s pass rate is around 1.5× the next-best model for the same cost per task. Even at its lowest effort setting, Opus 5 passes more tasks than any other model.&lt;/li&gt;&lt;li&gt;On &lt;strong&gt;OSWorld 2.0&lt;/strong&gt;, a computer use benchmark, Opus 5 outperforms every other model at any given cost, surpassing Fable 5’s best result at just over a third of the cost.&lt;/li&gt;&lt;/ul&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;It’s also our best and most cost-efficient model on several related evaluations:&lt;/p&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column&quot;&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-carousel&quot;&gt;&lt;div class=&quot;Tabs-module-scss-module__iIvFzq__tab-container&quot; role=&quot;tablist&quot; aria-label=&quot;Media carousel tabs&quot;&gt;&lt;button role=&quot;tab&quot; aria-selected=&quot;true&quot; aria-controls=&quot;panel-media-0&quot; id=&quot;tab-media-0&quot; class=&quot;Tabs-module-scss-module__iIvFzq__tab Tabs-module-scss-module__iIvFzq__active&quot;&gt;&lt;span class=&quot;caption&quot;&gt;ARC-AGI 3&lt;/span&gt;&lt;/button&gt;&lt;button role=&quot;tab&quot; aria-selected=&quot;false&quot; aria-controls=&quot;panel-media-1&quot; id=&quot;tab-media-1&quot; class=&quot;Tabs-module-scss-module__iIvFzq__tab&quot;&gt;&lt;span class=&quot;caption&quot;&gt;GDPval-AA v2&lt;/span&gt;&lt;/button&gt;&lt;button role=&quot;tab&quot; aria-selected=&quot;false&quot; aria-controls=&quot;panel-media-2&quot; id=&quot;tab-media-2&quot; class=&quot;Tabs-module-scss-module__iIvFzq__tab&quot;&gt;&lt;span class=&quot;caption&quot;&gt;OSWorld 2.0&lt;/span&gt;&lt;/button&gt;&lt;button role=&quot;tab&quot; aria-selected=&quot;false&quot; aria-controls=&quot;panel-media-3&quot; id=&quot;tab-media-3&quot; class=&quot;Tabs-module-scss-module__iIvFzq__tab&quot;&gt;&lt;span class=&quot;caption&quot;&gt;HLE&lt;/span&gt;&lt;/button&gt;&lt;button role=&quot;tab&quot; aria-selected=&quot;false&quot; aria-controls=&quot;panel-media-4&quot; id=&quot;tab-media-4&quot; class=&quot;Tabs-module-scss-module__iIvFzq__tab&quot;&gt;&lt;span class=&quot;caption&quot;&gt;AutomationBench&lt;/span&gt;&lt;/button&gt;&lt;button role=&quot;tab&quot; aria-selected=&quot;false&quot; aria-controls=&quot;panel-media-5&quot; id=&quot;tab-media-5&quot; class=&quot;Tabs-module-scss-module__iIvFzq__tab&quot;&gt;&lt;span class=&quot;caption&quot;&gt;DeepSearchQA&lt;/span&gt;&lt;/button&gt;&lt;/div&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-container&quot;&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-panel MediaCarousel-module-scss-module__S2ancq__active&quot; role=&quot;tabpanel&quot; id=&quot;media-panel-0&quot; aria-labelledby=&quot;media-tab-0&quot; aria-hidden=&quot;false&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;eager&quot; width=&quot;3840&quot; height=&quot;2160&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/b5e071ba6a9ce5628b4662f05484d1806a9fdc94-3840x2160.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/figure&gt;&lt;/div&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-panel&quot; role=&quot;tabpanel&quot; id=&quot;media-panel-1&quot; aria-labelledby=&quot;media-tab-1&quot; aria-hidden=&quot;true&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;eager&quot; width=&quot;3840&quot; height=&quot;2160&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/8c0870bfca0dfac1d81a20e0ebac7eb3eff6d554-3840x2160.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/figure&gt;&lt;/div&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-panel&quot; role=&quot;tabpanel&quot; id=&quot;media-panel-2&quot; aria-labelledby=&quot;media-tab-2&quot; aria-hidden=&quot;true&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;eager&quot; width=&quot;3840&quot; height=&quot;2160&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/44fac8bd76238d8c09305ec7fe1511670d45c6d6-3840x2160.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/figure&gt;&lt;/div&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-panel&quot; role=&quot;tabpanel&quot; id=&quot;media-panel-3&quot; aria-labelledby=&quot;media-tab-3&quot; aria-hidden=&quot;true&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;eager&quot; width=&quot;3840&quot; height=&quot;2160&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/368a6a6ae23e72deac37566b9d0166d062e7dde1-3840x2160.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/figure&gt;&lt;/div&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-panel&quot; role=&quot;tabpanel&quot; id=&quot;media-panel-4&quot; aria-labelledby=&quot;media-tab-4&quot; aria-hidden=&quot;true&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;3840&quot; height=&quot;2160&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/c7c726c5588b69c944dcc205bd1ba7ebdf8c2259-3840x2160.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/figure&gt;&lt;/div&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-panel&quot; role=&quot;tabpanel&quot; id=&quot;media-panel-5&quot; aria-labelledby=&quot;media-tab-5&quot; aria-hidden=&quot;true&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;3840&quot; height=&quot;2160&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/8ac95d8d4d6e68b6f5fdf04a09206defc877513e-3840x2160.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/figure&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Opus 5 is a meaningful improvement over Opus 4.8 for scientific research. It shows better performance than Opus 4.8 on every one of our life sciences evaluations, which cover topics including structural biology, organic chemistry, and bioinformatics. Its improvements are most notable on organic chemistry tasks, like inferring molecular structures from spectroscopy data (it scores 10.2 percentage points higher than Opus 4.8 on our internal benchmark), and on protein-related tasks like predicting how variations in a protein’s sequence affect how it functions (here, it scores 7.7 percentage points higher).&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Finally, Opus 5 is capable of producing much stronger visual outputs:&lt;/p&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column&quot;&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-carousel&quot;&gt;&lt;div class=&quot;Tabs-module-scss-module__iIvFzq__tab-container&quot; role=&quot;tablist&quot; aria-label=&quot;Media carousel tabs&quot;&gt;&lt;button role=&quot;tab&quot; aria-selected=&quot;true&quot; aria-controls=&quot;panel-media-0&quot; id=&quot;tab-media-0&quot; class=&quot;Tabs-module-scss-module__iIvFzq__tab Tabs-module-scss-module__iIvFzq__active&quot;&gt;&lt;span class=&quot;caption&quot;&gt;Wind tunnel&lt;/span&gt;&lt;/button&gt;&lt;button role=&quot;tab&quot; aria-selected=&quot;false&quot; aria-controls=&quot;panel-media-1&quot; id=&quot;tab-media-1&quot; class=&quot;Tabs-module-scss-module__iIvFzq__tab&quot;&gt;&lt;span class=&quot;caption&quot;&gt;Cell artifact&lt;/span&gt;&lt;/button&gt;&lt;/div&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-container&quot;&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-panel MediaCarousel-module-scss-module__S2ancq__active&quot; role=&quot;tabpanel&quot; id=&quot;media-panel-0&quot; aria-labelledby=&quot;media-tab-0&quot; aria-hidden=&quot;false&quot;&gt;&lt;div class=&quot;Video-module-scss-module__qJNyFq__post-wrapper&quot;&gt;&lt;figure class=&quot;Video-module-scss-module__qJNyFq__post-video-container&quot;&gt;&lt;!--$!--&gt;&lt;template data-dgst=&quot;BAILOUT_TO_CLIENT_SIDE_RENDERING&quot;&gt;&lt;/template&gt;&lt;!--/$--&gt;&lt;figcaption class=&quot;caption&quot;&gt;Opus 5 visualized the flow of air over aerodynamic (and non-aerodynamic) objects. Try different settings in the wind tunnel &lt;a href=&quot;https://assets.claude.ai/brand/artifacts/blog/opus/5-aeolus-demo.html&quot;&gt;here&lt;/a&gt;.&lt;/figcaption&gt;&lt;/figure&gt;&lt;/div&gt;&lt;/div&gt;&lt;div class=&quot;MediaCarousel-module-scss-module__S2ancq__media-panel&quot; role=&quot;tabpanel&quot; id=&quot;media-panel-1&quot; aria-labelledby=&quot;media-tab-1&quot; aria-hidden=&quot;true&quot;&gt;&lt;div class=&quot;Video-module-scss-module__qJNyFq__post-wrapper&quot;&gt;&lt;figure class=&quot;Video-module-scss-module__qJNyFq__post-video-container&quot;&gt;&lt;!--$!--&gt;&lt;template data-dgst=&quot;BAILOUT_TO_CLIENT_SIDE_RENDERING&quot;&gt;&lt;/template&gt;&lt;!--/$--&gt;&lt;figcaption class=&quot;caption&quot;&gt;Opus 5 built a simplified, interactive illustration of a cell. Explore its elements &lt;a href=&quot;https://assets.claude.ai/brand/artifacts/blog/opus/5-sectio-demo.html&quot;&gt;here&lt;/a&gt;. &lt;/figcaption&gt;&lt;/figure&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;working-with-claude-opus-5&quot;&gt;Working with Claude Opus 5&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Claude Opus 5 is much stronger at verifying its work and iterating carefully until it succeeds. In evaluations and early-access testing, we and our users found many examples of Opus 5’s agency and thoroughness:&lt;/p&gt;&lt;ul class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;li&gt;On one Frontier-Bench task, Opus 5 was given a drawing of a machine part and asked to write code to rebuild it as a 3D FreeCAD model. However, in this task, the model was intentionally given no way to directly &lt;em&gt;view&lt;/em&gt; the drawing. Opus 5 responded by writing its own computer vision pipeline to pull the geometry from the raw pixels, then reconstructed the full machine part. It succeeded in doing so repeatedly; no competing model with the same setup could solve it after five attempts.&lt;/li&gt;&lt;li&gt;Given a real bug in a popular open-source package manager, Opus 5 found the root cause and fixed an edge case that the community’s patch had missed. A competing model fixed only the surface symptom (not the underlying cause), then reported the bug resolved.&lt;/li&gt;&lt;li&gt;An engineer at a trading firm used Opus 5 to build a market data feed for a new exchange in a single session. Previous models could not complete this task at all, even given extensive plans from the engineer. Finding no live feed to validate against, Opus 5 even built its own test harness to check that its code parsed the exchange’s data correctly.&lt;/li&gt;&lt;/ul&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Below are further reports from our early-access customers on their experience of working with Opus 5:&lt;/p&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column&quot;&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-wrapper&quot;&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-container&quot;&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-track&quot;&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/ad249bca4e8e195e08764efc43ecbc586ca37482-143x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;On FrontierCode 1.1, Claude Opus 5 approaches Fable-level performance at half the cost. Within Devin, it also shows particular strength on difficult debugging and root-cause analysis tasks.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Scott Wu&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;CEO&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/f084c88e65466636019709c40cc477aadce2f718-151x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 delivers near Fable 5 intelligence at Opus speed and cost. On CursorBench it’s just under Fable 5 and has many of the same behaviors. We are excited to see how developers use it in Cursor.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Sualeh Asif&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Co-Founder&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/f343481e6a953bc7b5390e6d9f61cf387c2ceb11-103x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 topped Zapier’s AutomationBench leaderboard without spending more tokens than prior Claude models. It took a raw account-health workbook and ran a full churn-prevention sequence end to end: flagging at-risk accounts, alerting the right owner, and summarizing for retention ops. Previous models didn’t pass; Opus 5 hit 100%.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Wade Foster&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;CEO&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/efde24e5691e04ed84cb9c3fb91c1033a2e65af0-145x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;On our genomics analysis work, Claude Opus 5 behaves more like a careful scientist than any model we’ve run. It reaches for the right statistical tests to rule out confounders, cross-checks its own results by independent methods, and stays on track through long multi-step analyses.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Alfredo Andere&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;CEO&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/40a2a6a28afd8ac8fbf0e764b6bbf4ebf06a1977-133x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 came out ahead of every model in its family on our internal evals. It isn’t just better on our hardest agentic coding tasks, up 22% over Opus 4.7, it’s steadier, with far less variance run to run. For the millions of builders on Lovable, that consistency is the whole game. Reliable results, build after build.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Fabian Hedin&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Co-Founder&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/e0731da5f669896ec6823e665df2c360ea03115d-140x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 is the biggest leap in the Opus family since 4.5. On the same full-stack app builds, the front end shows it first: the best animations, games, and 3D work we have seen from an Opus model.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Madhav Jha&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Co-Founder and CTO&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/7fbed01e869d6a4faf97317a1fc4b74f7997c66e-78x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;We’re loving Claude Opus 5. For the kind of open-ended analytical work our agent handles, it’s a strict upgrade over Opus 4.8, and the gains are biggest exactly where it matters: the harder, vaguer tasks. Responses are clearer and more concise, and we see improved efficiency at higher effort levels too.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Izzy Miller&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;AI Research Lead&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/e360f8a29093a6b4fccdc006315035583e89f9ac-146x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 is a striking improvement over Opus 4.8 for the financial research workflows our analysts run every day. It stands out on numerical reasoning, table work, and sharper critical thinking where precision matters.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Shirley Zhang&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Senior AI Engineer, Applied AI&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/bf162513ba017e72d4e07b0cd7683b86c4c5bc88-60x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 delivers the industry intelligence and accuracy that is essential for the analysis of specialized enterprise content. Box found that Opus 5 outperforms Opus 4.8 by 8% and delivers notable performance gains in the data analysis (11% improvement) and due diligence (17% improvement) workflows that technology, healthcare, and public sector organizations rely on daily.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Ben Kus&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;CTO&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/d514853a44cf69f069306c98b558f214112c4ef3-91x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 is a clear generational step up from Opus 4.8. Over one weekend I gave it a chief-of-staff role over my dev environments: it built its own monitor, drove each box, and pulled me in only for the judgment calls.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Cristian Rivera&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Staff Software Engineer&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/04865ae02e70e9d8ca5a79fb49ae9263d58a7022-528x256.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 made large scale changes across our Fundamental Research Assistant codebase, adapting to feedback throughout an agentic workflow and explaining its reasoning more clearly than any model we’ve used. It handled work we would normally have broken into much smaller pieces.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Conor Kiernan&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;CTO&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/867075586d7f5ee37ee1c8c7b4bf0dadb34a54e2-666x192.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;On some of our hardest financial-modeling tasks, Claude Opus 5 is a clear step up from Opus 4.8 in both accuracy and efficiency. Its performance floor is materially higher, especially on deep finance domain logic. Across effort levels it averaged 9 percentage points higher accuracy with a third fewer turns and tool calls and 60% less time.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Richard Pham&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Evals and Product Lead&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/cc80b0a6f9534a34252756b93dd5a9bc26dd58f1-222x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 checks its own work the way a real frontend developer would. On our benchmark it opened its pages in a browser at desktop and phone widths, caught a product hidden below the mobile fold and an off-screen checkout button, and fixed both before handing the work back.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;AJ Orbach&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Co-Founder and CEO&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/6dfc3bd55cc5f9d5ebdd8d5437505ae4b8560412-120x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 is a clear step up in performance on legal agent work compared to prior Opus models, and we saw the biggest gains in practice areas like corporate governance and arbitration. We were also impressed with Opus 5’s ability to maintain quality at lower reasoning levels, achieving similar performance while generating 26% fewer tokens on average compared to Opus 4.8 at max reasoning.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Niko Grupen&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Head of Applied Research&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/beb4f74e935e111be9a63875ae7743aaea2cb0a2-88x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5’s biggest gains for us are on longer-horizon work: building a full deck, then revising it. Artifact quality is what decides which model we ship, and this is the clearest step up we’ve seen — better visual understanding, cleaner formatting, fewer slide issues.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Alex Wang&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Applied AI&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/18f900625532e1baaa3302bdf9539f73592bdf60-164x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5’s judgment is what stands out. Handing off a PR, it doesn’t rush to publish: it verifies the branches, checks the template, and thinks through test implications so the handoff is clean. The older models tended to jump ahead and get caught on our checks.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Zimu Li&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Member of Technical Staff&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/f69ebaa2d39165a909def91e572e7d9ec0088a9a-154x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;During a rearchitecting session, Claude Opus 5 pushed back on a design I proposed, and it didn’t fold when I insisted. Instead, it explained exactly what was valuable in my idea, narrowed its objection to a single design question, and proposed a compromise that kept the good part while fixing the flaw. That’s the kind of judgment that lets us trust it with less oversight.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Marquis Wang&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Principal AI Engineer&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/a0935a9396e8ec29b273be438cac14583c5999a6-130x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;On first-turn redlines, Claude Opus 5 scored the highest of any model we tested, nearly double Opus 4.8. Commenting is better too: on NDAs it gets to the redline in less time and with fewer passes, with accuracy maintained or better.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Ryan Tanenholz&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Member of Technical Staff&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/428460e52876e1ec0159ee37b5f5df71eee6472f-106x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 writes clean, tight diffs with no dead code, and it’s the stronger hazard spotter on subtle, codebase-specific issues. We’re adopting it for production workloads.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Neeraj Deshmukh&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Director of Engineering&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/f0dacc0d330bc402df7423a025a963b2a5e969d2-191x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;We will definitely migrate a number of use cases in Cosmos, our unified agent platform. We’re looking forward to increasingly using Claude Opus 5 for code review, and I am confident in saying we would rather people be using Opus 5 than Opus 4.8.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Igor Ostrovsky&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Co-Founder and CTO&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/921e6c04971bb083186c710c631b21946f39a96d-1280x275.webp&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;What stands out about Claude Opus 5 is judgment. It thinks harder before it writes a single line, catches its own logical faults during planning rather than after the fact, and reasons about why an answer is right, not just whether it works. It’s the clearest jump in problem-solving we’ve seen from one Claude model to the next, and we’re looking forward to seeing it adopted in JetBrains IDEs.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Denis Shiryaev&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Head of AI in IDE&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/fbd45dbecde0ed6e7c3bf8551df0525d87efd4de-127x64.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 is the strongest Opus model we’ve tested on our trading benchmark, and it gets there using roughly a seventh of the reasoning tokens and under half the latency of Opus 4.8. Better answers at a fraction of the compute.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Matt Nassr&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Head of Global Data Engineering and AI Transformation&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/c40e0aa477d2cf411c9f13ffd51f4549938ba0aa-106x32.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 lets monitoring agents manage parts of their own memory in production, making them more autonomous and reliable over longer horizons. The agent treats its context as a living document: after flagging a potential anomaly in one of our services, it re-checked its own assumption against production, found the signal was benign, wrote the correction into its memory, and retired its monitoring queries on its own.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Tanapat Ratanaruengjumrune&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;Manager, Applied AI&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;div class=&quot;Carousel-module-scss-module__hqckjG__carousel-item QuoteCarousel-module-scss-module__XVJWRG__with-logo bg-ivory-medium&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__logo-container&quot;&gt;&lt;img alt=&quot; logo&quot; loading=&quot;lazy&quot; width=&quot;120&quot; height=&quot;48&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; class=&quot;QuoteCarousel-module-scss-module__XVJWRG__company-logo&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/198c9eb920db5dc4581daefd3dc19d9fb51f6637-125x32.svg&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;/div&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-mark-container&quot;&gt;&lt;svg class=&quot;Icon-module-scss-module__lqbdHG__icon&quot; width=&quot;16&quot; height=&quot;16&quot; viewBox=&quot;0 0 37 31&quot;&gt;&lt;path d=&quot;M16.7999 4.81642C14.2986 5.45109 12.1333 6.45909 10.3039 7.84042C8.51192 9.18442 7.13059 10.8644 6.15992 12.8804C5.18926 14.8964 4.70392 17.1738 4.70392 19.7124H3.47192C3.47192 18.1444 3.95726 16.8938 4.92792 15.9604C5.93592 14.9898 7.27992 14.5044 8.95992 14.5044C10.3786 14.5044 11.6853 14.8591 12.8799 15.5684C14.0746 16.2778 15.0266 17.2298 15.7359 18.4244C16.4453 19.6191 16.7999 20.9258 16.7999 22.3444C16.7999 23.7631 16.4453 25.0698 15.7359 26.2644C15.0266 27.4591 14.0746 28.4111 12.8799 29.1204C11.6853 29.8298 10.3786 30.1844 8.95992 30.1844C7.24259 30.1844 5.69326 29.7364 4.31192 28.8404C2.96792 27.9444 1.90392 26.6938 1.11992 25.0884C0.373255 23.4831 -7.79331e-05 21.6911 -7.79331e-05 19.7124C-7.79331e-05 16.3524 0.690589 13.3097 2.07192 10.5844C3.49059 7.82175 5.45059 5.54442 7.95192 3.75242C10.4906 1.92309 13.4399 0.672418 16.7999 0.000417709V4.81642ZM36.9599 4.81642C34.4586 5.45109 32.2933 6.45909 30.4639 7.84042C28.6719 9.18442 27.2906 10.8644 26.3199 12.8804C25.3493 14.8964 24.8639 17.1738 24.8639 19.7124H23.6319C23.6319 18.1444 24.1173 16.8938 25.0879 15.9604C26.0959 14.9898 27.4399 14.5044 29.1199 14.5044C30.5386 14.5044 31.8453 14.8591 33.0399 15.5684C34.2346 16.2778 35.1866 17.2298 35.8959 18.4244C36.6053 19.6191 36.9599 20.9258 36.9599 22.3444C36.9599 23.7631 36.6053 25.0698 35.8959 26.2644C35.1866 27.4591 34.2346 28.4111 33.0399 29.1204C31.8453 29.8298 30.5386 30.1844 29.1199 30.1844C27.4026 30.1844 25.8533 29.7364 24.4719 28.8404C23.1279 27.9444 22.0639 26.6938 21.2799 25.0884C20.5333 23.4831 20.1599 21.6911 20.1599 19.7124C20.1599 16.3524 20.8506 13.3097 22.2319 10.5844C23.6506 7.82175 25.6106 5.54442 28.1119 3.75242C30.6506 1.92309 33.5999 0.672418 36.9599 0.000417709V4.81642Z&quot; fill=&quot;currentColor&quot;&gt;&lt;/path&gt;&lt;/svg&gt;&lt;/div&gt;&lt;blockquote class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-content&quot;&gt;&lt;div class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-text body-2 serif&quot;&gt;Claude Opus 5 is a strong agentic coding model built for long-running, multi-step work. It deeply understands your codebase, holds the thread across complex tasks, and pins down requirements for feature development and bug-fixing more effectively than Opus 4.8. Developers can now build with Opus 5 in Kiro, accessing its advanced capabilities to tackle ambitious projects.&lt;/div&gt;&lt;footer class=&quot;QuoteCarousel-module-scss-module__XVJWRG__quote-footer&quot;&gt;&lt;cite class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-info body-3&quot;&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-name&quot;&gt;Deepak Singh&lt;/span&gt;&lt;br&gt;&lt;span class=&quot;QuoteCarousel-module-scss-module__XVJWRG__speaker-title&quot;&gt;VP of Agentic AI&lt;/span&gt;&lt;/cite&gt;&lt;/footer&gt;&lt;/blockquote&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;alignment-and-safety&quot;&gt;Alignment and safety&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;em&gt;Alignment.&lt;/em&gt; During pre-deployment testing, our automated behavioral audit found Opus 5 to be our most aligned model to date (as shown in the graph below). It adheres to &lt;a href=&quot;https://www.anthropic.com/constitution&quot;&gt;Claude’s Constitution&lt;/a&gt; better than Opus 4.8, Sonnet 5, or Fable 5; exhibits the lowest rates of deceptive behavior; and is the least susceptible to being tricked into misuse. It’s also our safest model yet in terms of avoiding reckless actions that could have hard-to-reverse side effects.&lt;/p&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;3840&quot; height=&quot;2160&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/76d4af96516ffca2aceb4c1d0b0a83e2720d874b-3840x2160.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;em&gt;On our automated behavioral audit, Opus 5 scores 2.3 on overall misaligned behavior, the lowest of our recent models.&lt;/em&gt;&lt;/figcaption&gt;&lt;/figure&gt;&lt;/div&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;em&gt;Safety.&lt;/em&gt; Opus 5 does not advance the frontier in risky, dual-use capabilities. In rigorous evaluations conducted alongside private-sector and government partners, we found it remains behind Mythos 5 in both biology research and offensive cybersecurity. More information about these evaluations can be found in our &lt;a href=&quot;https://www.anthropic.com/claude-opus-5-system-card&quot;&gt;System Card&lt;/a&gt;.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;As with its predecessor, Opus 4.8, we’ve intentionally avoided training Opus 5 on cyber tasks. The model has nevertheless improved substantially on these tasks as a result of becoming more generally capable, and it comes close to Mythos 5 at &lt;em&gt;finding&lt;/em&gt; cybersecurity vulnerabilities. However, it remains substantially behind Mythos 5 on the &lt;em&gt;exploitation &lt;/em&gt;of those vulnerabilities—that is, in turning vulnerabilities into material cyber threats.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;This is illustrated by Opus 5’s performance on OSS-Fuzz, an evaluation we’ve developed to assess how well models can find and then exploit vulnerabilities without extensive human guidance. Although Mythos 5 and Opus 5 identify vulnerabilities with similar success, Opus 5’s score on the development of exploits is far behind that of Mythos 5.&lt;/p&gt;&lt;div class=&quot;Body-module-scss-module__z40yvW__media-column&quot;&gt;&lt;figure class=&quot;ImageWithCaption-module-scss-module__Duq99q__e-imageWithCaption&quot;&gt;&lt;img alt=&quot;&quot; loading=&quot;lazy&quot; width=&quot;3840&quot; height=&quot;2160&quot; decoding=&quot;async&quot; data-nimg=&quot;1&quot; src=&quot;https://www-cdn.anthropic.com/images/4zrzovbb/website/b22d18a4d2003401f96f866effd9a40b5518c4c5-3840x2160.png&quot; referrerpolicy=&quot;no-referrer&quot;&gt;&lt;figcaption class=&quot;caption&quot;&gt;&lt;em&gt;On OSS-Fuzz, one of our cybersecurity evaluations, Opus 5 is close to Mythos 5 at identifying software vulnerabilities (left), but is considerably less successful at developing exploits for them (right).&lt;/em&gt;&lt;/figcaption&gt;&lt;/figure&gt;&lt;/div&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;safeguards-for-opus-5&quot;&gt;&lt;strong&gt;Safeguards for Opus 5&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Claude Opus 5’s safeguards are designed to allow beneficial uses of the model in both cybersecurity and biology. They are similar to those we applied to Opus 4.8, with the exception of some stronger guardrails on a narrow range of cyber tasks.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;em&gt;Cybersecurity. &lt;/em&gt;Opus 5’s cyber classifiers are proportionally less restrictive than those on Fable 5. They allow Opus 5 to find vulnerabilities in source code, but block “binary-based” vulnerability scanning (a method more likely to be associated with malicious actors), penetration testing, and exploit generation.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Based on our testing, we expect the classifiers to intervene around 85% less often than they do for Fable 5. In &lt;a href=&quot;http://claude.ai/redirect/website.v1.df570219-c40f-4d18-8168-d62c33db99d2&quot;&gt;Claude.ai&lt;/a&gt;, Claude Code, and Claude Cowork, any flagged requests will fall back to Opus 4.8 by default. Fallbacks to Opus 4.8 can also be enabled on the API.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Our &lt;a href=&quot;https://support.claude.com/en/articles/14604842-real-time-cyber-safeguards-on-claude-opus-and-sonnet&quot;&gt;Cyber Verification Program&lt;/a&gt; (CVP) facilitates cybersecurity work that would otherwise be impeded by the model’s safeguards. Enterprises and researchers who are already part of the CVP have immediate access to a version of Opus 5 with fewer security restrictions.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;em&gt;Biology. &lt;/em&gt;Since Opus 5 has a similar suite of safeguards to Opus 4.8, it is now our most capable generally available model for scientific research. Nevertheless, the model still shows important limitations on long-running, autonomous research tasks, which is where we expect AI models to pose the most substantial biology-related risks. (Mythos 5 remains the stronger model for this type of biological work.) As part of this launch, biology-related requests that are blocked on Fable 5 will now route to Opus 5 rather than Opus 4.8.&lt;/p&gt;&lt;h2 class=&quot;Body-module-scss-module__z40yvW__reading-column headline-5 post-section&quot; id=&quot;getting-started&quot;&gt;&lt;strong&gt;Getting started&lt;/strong&gt;&lt;/h2&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Claude Opus 5 is available today on all platforms, priced at $5 per million input tokens and $25 per million output tokens (the same as Opus 4.8). Developers can get started with claude-opus-5 on the Claude API.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;It’s also offered in Fast mode, where it runs around 2.5 times the default speed. As with Opus 4.8, Fast mode is available at twice Opus 5’s base price on the Claude Platform and through usage credits in Claude Code.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Alongside Opus 5, we’re releasing two updates in beta:&lt;/p&gt;&lt;ul class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;&lt;li&gt;&lt;strong&gt;&lt;a href=&quot;https://platform.claude.com/docs/en/build-with-claude/mid-conversation-system-messages&quot;&gt;Mid-conversation tool changes&lt;/a&gt; on the Claude Platform.&lt;/strong&gt; Within a conversation, developers can now change which tools Claude can use without invalidating the prompt cache.&lt;/li&gt;&lt;li&gt;&lt;strong&gt;&lt;a href=&quot;https://platform.claude.com/docs/en/build-with-claude/refusals-and-fallback#server-side-fallback&quot;&gt;Automatic fallbacks&lt;/a&gt; on the API.&lt;/strong&gt; Users can now choose to have requests that are flagged by our safety classifiers on Opus 5 (or Fable 5) automatically route to another model. With automatic fallbacks on, API requests always route to the best available model by default rather than being blocked.&lt;/li&gt;&lt;/ul&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;Consistent with prior Opus models, Opus 5 does not have data retention requirements for general access.&lt;/p&gt;&lt;p class=&quot;Body-module-scss-module__z40yvW__reading-column body-2 serif post-text&quot;&gt;For more guidance on how to get the best out of Opus 5, see our &lt;a href=&quot;https://platform.claude.com/docs/en/build-with-claude/prompt-engineering/prompting-claude-opus-5&quot;&gt;prompting guide&lt;/a&gt;.&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;&lt;/div&gt;&lt;div class=&quot;page-wrapper PostDetail-module-scss-module__UQuRMa__postFooter&quot;&gt;&lt;div class=&quot;PostDetail-module-scss-module__UQuRMa__footnotes&quot;&gt;&lt;h4 class=&quot;headline-5&quot;&gt;Footnotes&lt;/h4&gt;&lt;p&gt;&lt;strong&gt;Frontier-Bench v0.1, Effort plot: &lt;/strong&gt;These results are from an internal run of Frontier-Bench v0.1, on the mini-SWE-agent harness and a GKE backend, mean reward over 5 attempts per task. Opus 4.8 served as fallback on safety-classifier refusals for Opus 5 and Fable 5.&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/article&gt;</description><link>https://www.anthropic.com/news/claude-opus-5</link><guid isPermaLink="false">https://www.anthropic.com/news/claude-opus-5</guid><pubDate>Thu, 23 Jul 2026 16:00:00 GMT</pubDate></item></channel></rss>